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2,3-diphosphoglycerate and Abnormality, Heart

2,3-diphosphoglycerate has been researched along with Abnormality, Heart in 6 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that children with cyanotic congenital heart disease and moderate hypoxemia, as a result of erythrocytosis, and adequate iron stores would have low serum erythropoietin titers, low tissue oxygen delivery, and normal red cell 2,3-diphosphoglycerate (DPG) concentrations."3.67Erythropoietin in cyanotic heart disease. ( Gidding, SS; Stockman, JA, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vichinsky, EP1
Pennathur-Das, R1
Nickerson, B1
Minor, M1
Kleman, K1
Higashino, S1
Lubin, B1
Hasan, RA1
Sarnaik, AP1
Meert, KL1
Dabbagh, S1
Simpson, P1
Makimi, M1
Harinck, E1
Hutter, PA1
Hoorntje, TM1
Simons, M1
Benatar, AA1
Fischer, JC1
de Bruijn, D1
Meijboom, EJ1
Takagi, Y1
Gomi, K1
Gidding, SS1
Stockman, JA1
Berman, W1
Wood, SC1
Yabek, SM1
Dillon, T1
Fripp, RR1
Burstein, R1

Other Studies

6 other studies available for 2,3-diphosphoglycerate and Abnormality, Heart

ArticleYear
Inadequate erythroid response to hypoxia in cystic fibrosis.
    The Journal of pediatrics, 1984, Volume: 105, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Biological Availability; Blood Sedimentation; Child; Chil

1984
Alterations in plasma phosphorus, red cell 2,3-diphosphoglycerate and P50 following open heart surgery.
    The Journal of cardiovascular surgery, 1994, Volume: 35, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Analysis of Variance; Blood Preservation; Blood Tran

1994
Air travel and adults with cyanotic congenital heart disease.
    Circulation, 1996, Jan-15, Volume: 93, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aerospace Medicine; Diphosphoglyceric Acids; Female; Hear

1996
[Clinical significance of 2,3-diphosphoglycerate analysis in blood cell chemical tests].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: 2,3-Diphosphoglycerate; Anemia; Diphosphoglyceric Acids; Erythrocytes; Female; Heart Defects, Congen

1989
Erythropoietin in cyanotic heart disease.
    American heart journal, 1988, Volume: 116, Issue:1 Pt 1

    Topics: 2,3-Diphosphoglycerate; Child; Child, Preschool; Cyanosis; Diphosphoglyceric Acids; Erythropoietin;

1988
Systemic oxygen transport in patients with congenital heart disease.
    Circulation, 1987, Volume: 75, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Biological Transport; Child; Child, Preschool; Diphosphoglyceric

1987