2,3-dimethoxy-1,4-naphthoquinone and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

2,3-dimethoxy-1,4-naphthoquinone has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 1 studies

2,3-dimethoxynaphthalene-1,4-dione : A naphthoquinone that is 1,4-naphthoquinone bearing two methoxy substituents at positions 2 and 3. Redox-cycling agent that induces intracellular superoxide anion formation and, depending on the concentration, induces cell proliferation, apoptosis or necrosis. Used to study the role of ROS in cell toxicity, apoptosis, and necrosis.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research

Studies (1)

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Other Studies

1 other study available for 2,3-dimethoxy-1,4-naphthoquinone and Leukemia, Myelogenous, Chronic, BCR-ABL Positive