2,3-dimethoxy-1,4-naphthoquinone has been researched along with Diabetes Mellitus, Gestational in 1 studies
2,3-dimethoxynaphthalene-1,4-dione : A naphthoquinone that is 1,4-naphthoquinone bearing two methoxy substituents at positions 2 and 3. Redox-cycling agent that induces intracellular superoxide anion formation and, depending on the concentration, induces cell proliferation, apoptosis or necrosis. Used to study the role of ROS in cell toxicity, apoptosis, and necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanism underlying pre-gestational diabetes-induced neural tube defects (NTDs) is still elusive." | 1.43 | High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects. ( Wu, Y; Yang, P; Yu, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, J | 1 |
| Wu, Y | 1 |
| Yang, P | 1 |
1 other study available for 2,3-dimethoxy-1,4-naphthoquinone and Diabetes Mellitus, Gestational
| Article | Year |
|---|---|
High glucose-induced oxidative stress represses sirtuin deacetylase expression and increases histone acetylation leading to neural tube defects.
Topics: Acetylation; Animals; Diabetes, Gestational; Epigenesis, Genetic; Female; Glucose; Group III Histone | 2016 |