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2,3-dimethoxy-1,4-naphthoquinone and Cystic Fibrosis

2,3-dimethoxy-1,4-naphthoquinone has been researched along with Cystic Fibrosis in 1 studies

2,3-dimethoxynaphthalene-1,4-dione : A naphthoquinone that is 1,4-naphthoquinone bearing two methoxy substituents at positions 2 and 3. Redox-cycling agent that induces intracellular superoxide anion formation and, depending on the concentration, induces cell proliferation, apoptosis or necrosis. Used to study the role of ROS in cell toxicity, apoptosis, and necrosis.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Voisin, G1
Bouvet, GF1
Legendre, P1
Dagenais, A1
Massé, C1
Berthiaume, Y1

Other Studies

1 other study available for 2,3-dimethoxy-1,4-naphthoquinone and Cystic Fibrosis

ArticleYear
Oxidative stress modulates the expression of genes involved in cell survival in ΔF508 cystic fibrosis airway epithelial cells.
    Physiological genomics, 2014, Sep-01, Volume: 46, Issue:17

    Topics: Apoptosis; Caspase 3; Caspase 7; Cell Line; Cell Survival; Cells, Cultured; Cystic Fibrosis; Cystic

2014