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2,3-dimethoxy-1,4-naphthoquinone and Colonic Neoplasms

2,3-dimethoxy-1,4-naphthoquinone has been researched along with Colonic Neoplasms in 1 studies

2,3-dimethoxynaphthalene-1,4-dione : A naphthoquinone that is 1,4-naphthoquinone bearing two methoxy substituents at positions 2 and 3. Redox-cycling agent that induces intracellular superoxide anion formation and, depending on the concentration, induces cell proliferation, apoptosis or necrosis. Used to study the role of ROS in cell toxicity, apoptosis, and necrosis.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
" The Caco-2 cell line was particularly vulnerable to NQ and MEN and displayed moderate toxic effects of DIM."1.30Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines. ( Karczewski, JM; Noordhoek, J; Peters, JG, 1999)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karczewski, JM1
Peters, JG1
Noordhoek, J1

Other Studies

1 other study available for 2,3-dimethoxy-1,4-naphthoquinone and Colonic Neoplasms

ArticleYear
Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines.
    Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

    Topics: Adenosine Triphosphate; Cell Survival; Colonic Neoplasms; Dicumarol; Glutathione; Glutathione Disulf

1999