2,3-dihydroxybenzoic acid has been researched along with Parkinson Disease in 4 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, H | 1 |
| Sarre, S | 1 |
| Ebinger, G | 1 |
| Michotte, Y | 1 |
| Martignoni, E | 2 |
| Blandini, F | 2 |
| Godi, L | 1 |
| Desideri, S | 1 |
| Pacchetti, C | 1 |
| Mancini, F | 1 |
| Nappi, G | 2 |
| Ricotti, R | 1 |
| di Jeso, F | 1 |
| Obata, T | 1 |
| Yamanaka, Y | 1 |
2 trials available for 2,3-dihydroxybenzoic acid and Parkinson Disease
| Article | Year |
|---|---|
Peripheral markers of oxidative stress in Parkinson's disease. The role of L-DOPA.
Topics: Antiparkinson Agents; Biomarkers; Blood Platelets; Dopamine; Female; Gentisates; Humans; Hydroxybenz | 1999 |
Determination of hydroxyl free radical formation in human platelets using high-performance liquid chromatography with electrochemical detection.
Topics: Adult; Antiparkinson Agents; Blood Platelets; Chromatography, High Pressure Liquid; Electrochemistry | 1999 |
2 other studies available for 2,3-dihydroxybenzoic acid and Parkinson Disease
| Article | Year |
|---|---|
Neuroprotective and neurotrophic effect of apomorphine in the striatal 6-OHDA-lesion rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressur | 2004 |
Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum.
Topics: 1-Methyl-4-phenylpyridinium; Allopurinol; Animals; Dopamine; Enzyme Inhibitors; Extracellular Space; | 2001 |