2,3-dihydroxybenzoic acid has been researched along with Nerve Degeneration in 4 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reserpine treatment alone did not change the levels of DA or 2,3-DHBA, while the combined treatment with both MPP(+) and reserpine clearly decreased 2,3-DHBA, as well as DA levels, compared to those in the group treated with MPP(+) alone." | 1.31 | Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation. ( Kinemuchi, H; Obata, T; Oreland, L; Yamanaka, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colado, MI | 2 |
| O'Shea, E | 1 |
| Esteban, B | 2 |
| Granados, R | 1 |
| Green, AR | 2 |
| Obata, T | 1 |
| Yamanaka, Y | 1 |
| Kinemuchi, H | 1 |
| Oreland, L | 1 |
| Camarero, J | 1 |
| Mechan, AO | 1 |
| Sanchez, V | 1 |
| Elliott, JM | 1 |
| Huang, M | 1 |
| Liu, W | 1 |
| Li, Q | 1 |
| Wu, CF | 1 |
4 other studies available for 2,3-dihydroxybenzoic acid and Nerve Degeneration
| Article | Year |
|---|---|
In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical scavenging mechanism.
Topics: Animals; Biotransformation; Body Temperature; Brain; Cerebral Cortex; Chlormethiazole; Corpus Striat | 1999 |
Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation.
Topics: 1-Methyl-4-phenylpyridinium; Adrenergic Uptake Inhibitors; Animals; Antifungal Agents; Cell Membrane | 2001 |
A study of the mechanisms involved in the neurotoxic action of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') on dopamine neurones in mouse brain.
Topics: Animals; Chlormethiazole; Corpus Striatum; Cyclic N-Oxides; Dizocilpine Maleate; Dopamine; Dose-Resp | 2001 |
Endogenous released ascorbic acid suppresses ethanol-induced hydroxyl radical production in rat striatum.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Ascorbic Acid; Drug Interactions; Ethanol; Extra | 2002 |