2,3-dihydroxybenzoic acid has been researched along with Myocardial Ischemia in 9 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicorandil has been reported to induce cardioprotection by opening the mitochondrial K(ATP) channels." | 1.33 | Nicorandil improves post-ischemic myocardial dysfunction in association with opening the mitochondrial K(ATP) channels and decreasing hydroxyl radicals in isolated rat hearts. ( Arai, M; Bao, N; Chen, XH; Fujiwara, H; Kawamura, I; Kobayashi, H; Lu, C; Minatoguchi, S; Takemura, G; Wang, N; Wu, DJ; Yasuda, S, 2006) |
| "Myocardial ischemia was induced by ligation of the descending branch of the left main coronary artery for 30 min." | 1.32 | Role of reactive oxygen species in the sensitivity of rat hypertrophied myocardium to ischemia. ( Gorodetskaya, EA; Kalenikova, EI; Medvedev, OS; Murashev, AN; Ruuge, EK, 2004) |
| "Prazosin was shown to have a *OH scavenging effect." | 1.30 | Prazosin attenuates hydroxyl radical generation in the rat myocardium. ( Obata, T; Yamanaka, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalenikova, EI | 2 |
| Gorodetskaya, EA | 2 |
| Murashev, AN | 1 |
| Ruuge, EK | 1 |
| Medvedev, OS | 1 |
| Lu, C | 1 |
| Minatoguchi, S | 1 |
| Arai, M | 1 |
| Wang, N | 1 |
| Chen, XH | 1 |
| Bao, N | 1 |
| Kawamura, I | 1 |
| Yasuda, S | 1 |
| Kobayashi, H | 1 |
| Wu, DJ | 1 |
| Takemura, G | 1 |
| Fujiwara, H | 1 |
| Obata, T | 5 |
| Hosokawa, H | 2 |
| Soeda, T | 1 |
| Karashima, K | 1 |
| Uchida, Y | 1 |
| Yamanaka, Y | 5 |
| Glantz, L | 1 |
| Ginosar, Y | 1 |
| Chevion, M | 1 |
| Gozal, Y | 1 |
| Elami, A | 1 |
| Navot, N | 1 |
| Kitrossky, N | 1 |
| Drenger, B | 1 |
9 other studies available for 2,3-dihydroxybenzoic acid and Myocardial Ischemia
| Article | Year |
|---|---|
Role of reactive oxygen species in the sensitivity of rat hypertrophied myocardium to ischemia.
Topics: Animals; Cardiac Output; Cardiomegaly; Catechols; Chromatography, High Pressure Liquid; Hydroxybenzo | 2004 |
Nicorandil improves post-ischemic myocardial dysfunction in association with opening the mitochondrial K(ATP) channels and decreasing hydroxyl radicals in isolated rat hearts.
Topics: Animals; Heart Ventricles; Hydroxybenzoates; Hydroxyl Radical; In Vitro Techniques; Male; Myocardial | 2006 |
Myocardial microdialysis of salicylic acid to detect hydroxyl radical generation during ischemia.
Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Gentisates; Hydroxybenzoates; Hydroxyl Radical; | 1995 |
In vivo monitoring of norepinephrine and .OH generation on myocardial ischemic injury by dialysis technique.
Topics: Animals; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Microdialysis; Myocardial Ischemia; Myocard | 1994 |
Halothane prevents postischemic production of hydroxyl radicals in the canine heart.
Topics: Anesthetics, Inhalation; Animals; Dogs; Gentisates; Halothane; Hydroxybenzoates; Hydroxyl Radical; M | 1997 |
Prazosin attenuates hydroxyl radical generation in the rat myocardium.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Hydroxybenzoates; Hydroxyl Radical; Iro | 1999 |
Block of cardiac ATP-sensitive K(+) channels reduces hydroxyl radicals in the rat myocardium.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Cromakalim; Decano | 2000 |
Formation of hydroxyl radicals during myocardial reperfusion after experimental ischemia of different duration.
Topics: Animals; Hydroxybenzoates; Hydroxyl Radical; Male; Microdialysis; Myocardial Ischemia; Myocardial Re | 2001 |
Iron (III) attenuates hydroxyl radical generation accompanying non-enzymatic oxidation of noradrenaline in the rat heart.
Topics: Animals; Female; Ferric Compounds; Hydroxybenzoates; Hydroxyl Radical; Intracellular Fluid; Male; Mi | 2002 |