2,3-dihydroxybenzoic acid has been researched along with Disease Models, Animal in 19 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was performed to assess the prophylactic effect of baicalin, a flavonoid compound, in an animal model of heatstroke." | 7.74 | The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007) |
| "In contrast, all vehicle-pretreated heatstroke animals had lower levels of mean arterial pressure, cerebral perfusion pressure, cerebral blood flow, and brain PO(2)." | 5.34 | The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007) |
| "Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle." | 3.79 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "The present study was performed to assess the prophylactic effect of baicalin, a flavonoid compound, in an animal model of heatstroke." | 3.74 | The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007) |
| " After a single injection of PTZ at a dose evoking clonic-tonic seizures, PBN did not modify either the formation of free hydroxyl radicals measured by the levels of 2,3-dihydroxybenzoic acid (DHBA) and 2,5-DHBA or the susceptibility to PTZ." | 3.72 | The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone. ( Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R, 2004) |
| "The magnolol-treated rats also exhibited decreased cerebral infarction volume and neuronal apoptosis and increased antiapoptosis-associated factor TGF-β1 expression." | 1.39 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle." | 1.39 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "Excessive alcohol consumption causes alcoholic fatty liver disease (AFLD)." | 1.39 | Metabolomics of ginger essential oil against alcoholic fatty liver in mice. ( Kuo, CH; Lin, SH; Liu, CT; Raghu, R; Sheen, LY; Tseng, YJ; Wang, SY, 2013) |
| "In contrast, all vehicle-pretreated heatstroke animals had lower levels of mean arterial pressure, cerebral perfusion pressure, cerebral blood flow, and brain PO(2)." | 1.34 | The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke. ( Chang, CP; Cheng, BC; Hsu, CC; Huang, WT; Lin, MT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, CC | 1 |
| Lin, KC | 1 |
| Lin, BS | 1 |
| Chio, CC | 1 |
| Kuo, JR | 1 |
| Liu, CT | 1 |
| Raghu, R | 1 |
| Lin, SH | 1 |
| Wang, SY | 1 |
| Kuo, CH | 1 |
| Tseng, YJ | 1 |
| Sheen, LY | 1 |
| Wang, Y | 1 |
| Yuan, L | 1 |
| Liu, P | 1 |
| Zhao, M | 1 |
| Wang, CT | 1 |
| Lin, HJ | 1 |
| Cheng, BC | 2 |
| Lin, MT | 2 |
| Chang, CP | 2 |
| Adhirajan, N | 1 |
| Shanmugasundaram, N | 1 |
| Shanmuganathan, S | 1 |
| Babu, M | 1 |
| Kwon, TH | 1 |
| Chao, DL | 1 |
| Malloy, K | 1 |
| Sun, D | 1 |
| Alessandri, B | 1 |
| Bullock, MR | 1 |
| Hashimoto, T | 1 |
| Yonetani, M | 1 |
| Nakamura, H | 1 |
| Rauca, C | 1 |
| Wiswedel, I | 1 |
| Zerbe, R | 1 |
| Keilhoff, G | 1 |
| Krug, M | 1 |
| Yuan, H | 1 |
| Sarre, S | 1 |
| Ebinger, G | 1 |
| Michotte, Y | 1 |
| Dahchour, A | 1 |
| Lallemand, F | 1 |
| Ward, RJ | 1 |
| De Witte, P | 1 |
| Huang, WT | 1 |
| Hsu, CC | 1 |
| Himori, N | 1 |
| Suzuki, T | 1 |
| Ueno, K | 1 |
| Cai, Q | 1 |
| Takemura, G | 1 |
| Ashraf, M | 1 |
| Lancelot, E | 1 |
| Callebert, J | 1 |
| Revaud, ML | 1 |
| Boulu, RG | 1 |
| Plotkine, M | 1 |
| Kantrow, SP | 1 |
| Taylor, DE | 1 |
| Carraway, MS | 1 |
| Piantadosi, CA | 1 |
| Bellaire, BH | 1 |
| Elzer, PH | 1 |
| Baldwin, CL | 1 |
| Roop, RM | 1 |
| Heim, C | 1 |
| Zhang, J | 1 |
| Lan, J | 1 |
| Sieklucka, M | 1 |
| Kurz, T | 1 |
| Riederer, P | 1 |
| Gerlach, M | 1 |
| Sontag, KH | 1 |
| Udassin, R | 1 |
| Ariel, I | 1 |
| Haskel, Y | 1 |
| Kitrossky, N | 1 |
| Chevion, M | 1 |
| Pearce, RA | 1 |
| Finley, RJ | 1 |
| Mustard, RA | 1 |
| Duff, JH | 1 |
19 other studies available for 2,3-dihydroxybenzoic acid and Disease Models, Animal
| Article | Year |
|---|---|
Resuscitation from experimental traumatic brain injury by magnolol therapy.
Topics: Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Disease Models, Animal; Free Radical Scaveng | 2013 |
Metabolomics of ginger essential oil against alcoholic fatty liver in mice.
Topics: Animals; Disease Models, Animal; Fatty Liver, Alcoholic; Humans; Hydroxybenzoates; Liver; Male; Meta | 2013 |
Delayed hyperoxic ventilation attenuates oxygen-induced free radical accumulation during early reperfusion after global brain ischemia.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Carotid Artery Diseases; Cell Respiration; Disease | 2015 |
Attenuating systemic inflammatory markers in simulated high-altitude exposure by heat shock protein 70-mediated hypobaric hypoxia preconditioning in rats.
Topics: Altitude Sickness; Animals; Biomarkers; Disease Models, Animal; E-Selectin; HSP70 Heat-Shock Protein | 2015 |
Collagen-based wound dressing for doxycycline delivery: in-vivo evaluation in an infected excisional wound model in rats.
Topics: Animals; Anti-Bacterial Agents; Bandages, Hydrocolloid; Collagen; Colony Count, Microbial; Disease M | 2009 |
Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat.
Topics: Animals; Antioxidants; Brain Chemistry; Brain Damage, Chronic; Cyclic N-Oxides; Disease Models, Anim | 2003 |
Selective brain hypothermia protects against hypoxic-ischemic injury in newborn rats by reducing hydroxyl radical production.
Topics: Animals; Animals, Newborn; Brain; Cell Count; Cell Survival; Cerebrovascular Circulation; Disease Mo | 2003 |
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Li | 2004 |
Neuroprotective and neurotrophic effect of apomorphine in the striatal 6-OHDA-lesion rat model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressur | 2004 |
Production of reactive oxygen species following acute ethanol or acetaldehyde and its reduction by acamprosate in chronically alcoholized rats.
Topics: Acamprosate; Acetaldehyde; Alcohol Deterrents; Alcoholism; Animals; Disease Models, Animal; Ethanol; | 2005 |
The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Brain Chemistry; Catechols; Cytoki | 2007 |
Aniracetam, a pyrrolidinone-type cognition enhancer, attenuates the hydroxyl free radical formation in the brain of mice with brain ischaemia.
Topics: Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopami | 1995 |
Antioxidative properties of histidine and its effect on myocardial injury during ischemia/reperfusion in isolated rat heart.
Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Chromatography, High Pressure Liquid; Disease Models | 1995 |
Detection of hydroxyl radicals in rat striatum during transient focal cerebral ischemia: possible implication in tissue damage.
Topics: Analysis of Variance; Animals; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Gentisa | 1995 |
Oxidative metabolism in rat hepatocytes and mitochondria during sepsis.
Topics: Animals; Cecum; Cell Separation; Disease Models, Animal; Electron Transport; Enzyme Induction; Hydro | 1997 |
The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB/c mice.
Topics: Animals; Brucella abortus; Brucellosis; Disease Models, Animal; Female; Genes, Bacterial; Hydroxyben | 1999 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu | 2000 |
Salicylate as an in vivo free radical trap: studies on ischemic insult to the rat intestine.
Topics: Animals; Disease Models, Animal; Free Radicals; Gentisates; Hydroxides; Hydroxybenzoates; Hydroxyl R | 1991 |
2,3-Dihydroxybenzoic acid. Effect on mortality rate in a septic rat model.
Topics: Abdomen; Animals; Bacterial Infections; Dimethyl Sulfoxide; Disease Models, Animal; Drug Therapy, Co | 1985 |