2,3-dihydroxybenzoic acid has been researched along with Brain Injuries in 4 studies
2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle." | 3.79 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "The magnolol-treated rats also exhibited decreased cerebral infarction volume and neuronal apoptosis and increased antiapoptosis-associated factor TGF-β1 expression." | 1.39 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle." | 1.39 | Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013) |
| "Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia." | 1.30 | Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia. ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, CC | 1 |
| Lin, KC | 1 |
| Lin, BS | 1 |
| Chio, CC | 1 |
| Kuo, JR | 1 |
| Yang, ZJ | 1 |
| Xie, Y | 1 |
| Bosco, GM | 1 |
| Chen, C | 1 |
| Camporesi, EM | 1 |
| Globus, MY | 1 |
| Alonso, O | 1 |
| Dietrich, WD | 1 |
| Busto, R | 1 |
| Ginsberg, MD | 1 |
| Li, PA | 1 |
| Liu, GJ | 1 |
| He, QP | 1 |
| Floyd, RA | 1 |
| Siesjö, BK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Enriched Oxygen Mixtures and Exercise on Oxidative Stress and Stem Cells Proliferation in Athletes.[NCT04366427] | Phase 2 | 42 participants (Actual) | Interventional | 2020-09-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for 2,3-dihydroxybenzoic acid and Brain Injuries
| Article | Year |
|---|---|
Resuscitation from experimental traumatic brain injury by magnolol therapy.
Topics: Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Disease Models, Animal; Free Radical Scaveng | 2013 |
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl R | 2010 |
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radica | 1995 |
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hype | 1999 |