Page last updated: 2024-10-15

2,3-dihydroxybenzoic acid and Acute Brain Injuries

2,3-dihydroxybenzoic acid has been researched along with Acute Brain Injuries in 4 studies

2,3-dihydroxybenzoic acid: RN given refers to parent cpd
dihydroxybenzoic acid : Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives.
2,3-dihydroxybenzoic acid : A dihydroxybenzoic acid that is benzoic acid substituted by hydroxy groups at positions 2 and 3. It occurs naturally in Phyllanthus acidus and in the aquatic fern Salvinia molesta.

Research Excerpts

ExcerptRelevanceReference
"Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle."3.79Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013)
"The magnolol-treated rats also exhibited decreased cerebral infarction volume and neuronal apoptosis and increased antiapoptosis-associated factor TGF-β1 expression."1.39Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013)
"Traumatic brain injuries were induced in anesthetized male Sprague-Dawley rats using fluid percussion, and the rats were divided into groups treated with magnolol (2 mg/kg, intravenously) or vehicle."1.39Resuscitation from experimental traumatic brain injury by magnolol therapy. ( Chio, CC; Kuo, JR; Lin, BS; Lin, KC; Wang, CC, 2013)
"Preischemic hyperglycemia is known to aggravate brain damage resulting from transient ischemia."1.30Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia. ( Floyd, RA; He, QP; Li, PA; Liu, GJ; Siesjö, BK, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, CC1
Lin, KC1
Lin, BS1
Chio, CC1
Kuo, JR1
Yang, ZJ1
Xie, Y1
Bosco, GM1
Chen, C1
Camporesi, EM1
Globus, MY1
Alonso, O1
Dietrich, WD1
Busto, R1
Ginsberg, MD1
Li, PA1
Liu, GJ1
He, QP1
Floyd, RA1
Siesjö, BK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Enriched Oxygen Mixtures and Exercise on Oxidative Stress and Stem Cells Proliferation in Athletes.[NCT04366427]Phase 242 participants (Actual)Interventional2020-09-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for 2,3-dihydroxybenzoic acid and Acute Brain Injuries

ArticleYear
Resuscitation from experimental traumatic brain injury by magnolol therapy.
    The Journal of surgical research, 2013, Volume: 184, Issue:2

    Topics: Animals; Apoptosis; Biphenyl Compounds; Brain Injuries; Disease Models, Animal; Free Radical Scaveng

2013
Hyperbaric oxygenation alleviates MCAO-induced brain injury and reduces hydroxyl radical formation and glutamate release.
    European journal of applied physiology, 2010, Volume: 108, Issue:3

    Topics: Animals; Blood Pressure; Brain; Brain Injuries; Gentisates; Glutamates; Hydroxybenzoates; Hydroxyl R

2010
Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia.
    Journal of neurochemistry, 1995, Volume: 65, Issue:4

    Topics: Animals; Brain Injuries; Free Radicals; Gentisates; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radica

1995
Production of hydroxyl free radical by brain tissues in hyperglycemic rats subjected to transient forebrain ischemia.
    Free radical biology & medicine, 1999, Volume: 27, Issue:9-10

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Hype

1999