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2,3-bis(4-hydroxyphenyl)-propionitrile and Disease Models, Animal

2,3-bis(4-hydroxyphenyl)-propionitrile has been researched along with Disease Models, Animal in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (42.86)29.6817
2010's11 (52.38)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Du, M; Feng, A; Gu, J; Schmull, S; Shan, J; Xue, S1
Coulombe, PA; Hakim, JMC; Kerns, ML; Lu, RG; Zieman, A1
Bukovac, S; Green, MR; Guerin, C; Isedowo, R; Lillie, L; McCormick, CM; Nar, NN; Said, SA; Simone, JJ; Stuart, JA1
Cao, Y; Itoh, N; Spence, RD; Voskuhl, RR; Wisdom, AJ1
Bibak, B; Gholamhoseinian, A; Keshavarzi, Z; Khaksari, M1
Chen, J; Chen, W; Qiu, J; Tao, J; Xu, L; Yang, F; Zhao, N; Zhu, Y1
Hasan, DM; Hashimoto, T; Kanematsu, Y; Kitazato, KT; Kudo, M; Liang, EI; Makino, H; Murakami, S; Nagahiro, S; Pena Silva, RA; Shikata, F; Shimada, K; Tada, Y; Wada, K1
Furukawa, H; Hasan, DM; Hashimoto, T; Kitazato, KT; Kudo, M; Kung, DK; Lawton, MT; Liang, EI; Makino, H; Murakami, S; Nagahiro, S; Shimada, K; Tada, Y; Wada, K1
Frye, CA; Koonce, CJ; Walf, AA1
Barr, AM; Galea, LA; Green, AD1
Du, S; Sandoval, F; Trinh, P; Voskuhl, RR1
Borra, F; Gallo, D; Giardullo, P; Leonardi, S; Majo, VD; Mancuso, M; Pasquali, E; Pazzaglia, S; Prisco, MG; Saran, A; Scambia, G; Stefano, ID; Tanori, M1
Hunter, JC; Korzick, DH; Miller-Lee, JL; Tomicek, NJ1
Cao, DY; Ji, Y; Tang, B; Traub, RJ1
Chaudry, IH; Choudhry, MA; Hsieh, YC; Schwacha, MG; Shimizu, T; Suzuki, T; Yu, HP1
Bland, KI; Chaudry, IH; Choudhry, MA; Hsieh, YC; Shimizu, T; Suzuki, T; Yu, HP1
Li, J; McMurray, RW1
Lee, R; Morales, LB; Tiwari-Woodruff, S; Voskuhl, RR1
Carswell, HV; Farr, TD; Gsell, W; Macrae, IM1
Cruthirds, DF; Ewell, E; Handa, RJ; Larco, DO; Walters, K; Wegorzewska, IN; Weiser, MJ; Wu, TJ1
Bland, KI; Chaudry, IH; Choudhry, MA; Shimizu, T; Suzuki, T; Yokoyama, Y; Yu, HP1

Other Studies

21 other study(ies) available for 2,3-bis(4-hydroxyphenyl)-propionitrile and Disease Models, Animal

ArticleYear
Oestrogen Receptor β Activation Protects Against Myocardial Infarction via Notch1 Signalling.
    Cardiovascular drugs and therapy, 2020, Volume: 34, Issue:2

    Topics: Animals; Apoptosis; Disease Models, Animal; Estrogen Receptor beta; Estrogens; Fibrosis; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Nitriles; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Signal Transduction; Vascular Endothelial Growth Factor A; Ventricular Function, Left; Ventricular Remodeling

2020
Sexual Dimorphism in Response to an NRF2 Inducer in a Model for Pachyonychia Congenita.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:5

    Topics: Animals; Disease Models, Animal; Estrogen Receptor alpha; Female; Glutathione; Humans; Isothiocyanates; Keratin-16; Keratoderma, Palmoplantar; Male; Mice; NF-E2-Related Factor 2; Nitriles; Pachyonychia Congenita; Propionates; Sex Characteristics; Sulfoxides

2018
Effects of long-term dietary administration of estrogen receptor-beta agonist diarylpropionitrile on ovariectomized female ICR (CD-1) mice.
    GeroScience, 2018, Volume: 40, Issue:4

    Topics: Aging; Animals; Behavior, Animal; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Estrogen Receptor beta; Female; Frailty; Mice; Mice, Inbred ICR; Nitriles; Ovariectomy; Propionates; Random Allocation; Reference Values

2018
Estrogen receptor-β ligand treatment after disease onset is neuroprotective in the multiple sclerosis model.
    Journal of neuroscience research, 2013, Volume: 91, Issue:7

    Topics: Animals; Axons; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Nitriles; Peptide Fragments; Propionates; Receptors, Estrogen; Severity of Illness Index

2013
The effect of female sexual hormones on the intestinal and serum cytokine response after traumatic brain injury: different roles for estrogen receptor subtypes.
    Canadian journal of physiology and pharmacology, 2013, Volume: 91, Issue:9

    Topics: Animals; Brain Injuries; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Replacement Therapy; Estrogens; Female; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Intestinal Mucosa; Intestines; Nitriles; Ovariectomy; Phenols; Progesterone; Propionates; Pyrazoles; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2013
Estradiol decreases rat depressive behavior by estrogen receptor beta but not alpha: no correlation with plasma corticosterone.
    Neuroreport, 2014, Jan-22, Volume: 25, Issue:2

    Topics: Animals; Corticosterone; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Exploratory Behavior; Female; Maze Learning; Nitriles; Ovariectomy; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Swimming

2014
Estrogen protects against intracranial aneurysm rupture in ovariectomized mice.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:6

    Topics: Aged; Aneurysm, Ruptured; Animals; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Fulvestrant; Humans; Intracranial Aneurysm; Mice; Mice, Inbred C57BL; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Ovariectomy; Phenols; Pyrazoles; Subarachnoid Hemorrhage

2014
Roles of estrogen in the formation of intracranial aneurysms in ovariectomized female mice.
    Neurosurgery, 2014, Volume: 75, Issue:6

    Topics: Animals; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Intracranial Aneurysm; Male; Mice; Mice, Knockout; Nitriles; Ovariectomy; Phenols; Propionates; Pyrazoles; Sex Characteristics

2014
Estradiol or diarylpropionitrile decrease anxiety-like behavior of wildtype, but not estrogen receptor beta knockout, mice.
    Behavioral neuroscience, 2008, Volume: 122, Issue:5

    Topics: Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Estradiol; Estrogen Receptor beta; Estrogens; Exploratory Behavior; Female; Interpersonal Relations; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitriles; Ovariectomy; Pain Measurement; Propionates; Radioimmunoassay

2008
Role of estradiol withdrawal in 'anhedonic' sucrose consumption: a model of postpartum depression.
    Physiology & behavior, 2009, May-25, Volume: 97, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Body Weight; Depression, Postpartum; Disease Models, Animal; Drug Administration Routes; Drug Administration Schedule; Estradiol; Female; Food Preferences; Imipramine; Nitriles; Ovariectomy; Postpartum Period; Pregnancy; Propionates; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome; Sucrose; Sweetening Agents; Time Factors

2009
Additive effects of combination treatment with anti-inflammatory and neuroprotective agents in experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 2010, Feb-26, Volume: 219, Issue:1-2

    Topics: Analysis of Variance; Animals; Antigens, CD; Antigens, Differentiation; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Encephalomyelitis, Autoimmune, Experimental; Female; Glycoproteins; Immunologic Factors; Integrin alpha4beta1; Interferon-beta; Luminescent Proteins; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; Myelin Basic Protein; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Neutrophil Infiltration; Nitriles; Peptide Fragments; Propionates; Severity of Illness Index; Spinal Cord

2010
The estrogen receptor beta agonist diarylpropionitrile (DPN) inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways.
    Cancer letters, 2011, Sep-28, Volume: 308, Issue:2

    Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Estrogen Receptor beta; Female; Immunohistochemistry; Male; Medulloblastoma; Mice; Nitriles; Propionates; Signal Transduction

2011
Estrogen receptor beta does not influence ischemic tolerance in the aged female rat heart.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:1

    Topics: Age Factors; Aging; Animals; Disease Models, Animal; Estradiol; Estrogen Receptor beta; Female; HEK293 Cells; Humans; Mice; Myocardial Reperfusion Injury; Myocardium; Nitriles; Ovariectomy; Propionates; Rats; Rats, Inbred F344; Recovery of Function; RNA, Messenger; Time Factors; Transfection; Ventricular Function, Left; Ventricular Pressure

2013
Estrogen receptor β activation is antinociceptive in a model of visceral pain in the rat.
    The journal of pain, 2012, Volume: 13, Issue:7

    Topics: Animals; Disease Models, Animal; Estradiol; Estrogen Receptor beta; Female; Fulvestrant; Nitriles; Nociception; Oxazoles; Phenols; Posterior Horn Cells; Propionates; Rats; Rats, Sprague-Dawley; Visceral Pain

2012
Salutary effects of estrogen receptor-beta agonist on lung injury after trauma-hemorrhage.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:5

    Topics: Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Estradiol; Estrogen Receptor beta; Hemorrhage; Humans; Interleukin-6; L-Lactate Dehydrogenase; Male; Nitrates; Nitriles; Nitrites; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome

2006
17 beta-estradiol administration following trauma-hemorrhage prevents the increase in Kupffer cell cytokine production and MAPK activation predominately via estrogen receptor-alpha.
    Surgery, 2006, Volume: 140, Issue:2

    Topics: Animals; Cytokines; Disease Models, Animal; Estradiol; Hemorrhage; Kupffer Cells; Male; Mitogen-Activated Protein Kinases; Nitriles; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Wounds, Penetrating

2006
Effects of estrogen receptor subtype-selective agonists on autoimmune disease in lupus-prone NZB/NZW F1 mouse model.
    Clinical immunology (Orlando, Fla.), 2007, Volume: 123, Issue:2

    Topics: Albuminuria; Animals; Antibodies, Antinuclear; Blood Urea Nitrogen; Body Weight; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Immune System; Immunoglobulin G; Immunologic Factors; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Nitriles; Ovariectomy; Phenols; Prolactin; Propionates; Pyrazoles; Receptors, Estrogen; Survival Analysis

2007
Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Sep-11, Volume: 104, Issue:37

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Homozygote; Humans; Immunohistochemistry; Ligands; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitriles; Ovariectomy; Phenols; Propionates; Pyrazoles; Selective Estrogen Receptor Modulators

2007
Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia.
    Brain research, 2007, Dec-14, Volume: 1185

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Estrogen Antagonists; Female; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Neurologic Examination; Nitriles; Ovariectomy; Propionates; Psychomotor Performance; Rats; Severity of Illness Index

2007
Postovariectomy weight gain in female rats is reversed by estrogen receptor alpha agonist, propylpyrazoletriol.
    American journal of obstetrics and gynecology, 2008, Volume: 199, Issue:1

    Topics: Animals; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Nitriles; Ovariectomy; Phenols; Propionates; Pyrazoles; Rats; Rats, Long-Evans; Receptors, Estrogen; Weight Gain

2008
The role of estrogen receptor subtypes on hepatic neutrophil accumulation following trauma-hemorrhage: direct modulation of CINC-1 production by Kupffer cells.
    Cytokine, 2008, Volume: 43, Issue:1

    Topics: Animals; Cell Movement; Chemokine CXCL1; Disease Models, Animal; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Hemorrhage; Kupffer Cells; Liver Diseases; Male; Neutrophil Infiltration; Nitriles; Phenols; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley

2008