2,3-bis(3'-hydroxybenzyl)butyrolactone and Breast Cancer

2,3-bis(3'-hydroxybenzyl)butyrolactone has been researched along with Breast Cancer in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.56)	18.7374
1990's	5 (9.26)	18.2507
2000's	26 (48.15)	29.6817
2010's	18 (33.33)	24.3611
2020's	2 (3.70)	2.80

Authors

Authors	Studies
Hatwik, J; Limaye, AM; Patil, HN	1
Becher, H; Behrens, S; Chang-Claude, J; Gonzalez-Maldonado, S; Hell, R; Huebner, M; Hüsing, A; Jaskulski, S; Jung, AY; Obi, N; Poschet, G	1
Chang-Claude, J; Herpel, E; Jaskulski, S; Johnson, T; Jung, AY; Rudolph, A; Sinn, P; Thöne, K	1
Bach Knudsen, KE; Eriksen, AK; Frederiksen, K; Hansen, L; Holm, M; Kyrø, C; Nørskov, NP; Olsen, A; Tjønneland, A	1
Behrens, S; Chang-Claude, J; Flesch-Janys, D; Jaskulski, S; Johnson, T; Jung, AY; Kaaks, R; Sookthai, D; Thöne, K	1
Abrahamsson, A; Dabrosin, C; Lindahl, G	1
Eliassen, AH; Franke, AA; Hankinson, SE; Rice, MS; Rosner, BA; Terry, KL; Tworoger, SS; Willett, WC; Xie, J	1
Behrens, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Heinz, J; Johnson, TS; Kaaks, R; Linseisen, J; Obi, N; Seibold, P; Vrieling, A	1
Hu, XJ; Li, Y; Liu, CM; Xiong, XY	1
Fu, Q; Hu, Y; Lv, Q; Qiu, J; Tan, Q; Tang, S; Yang, J; Zhang, J; Zhou, Y	1
Bigdeli, B; Goliaei, B; Haghparast, A; Jooyan, N; Mamashli, F; Masoudi-Khoram, N; Nikoofar, A; Rouhani, M	1
Adlercreutz, H; Borgquist, S; Ericson, U; Gullberg, B; Landberg, G; Olsson, H; Sonestedt, E; Wirfält, E	1
Adlercreutz, H; Carlson, J; Ericson, U; Gullberg, B; Harlid, S; Ivarsson, MI; Olsson, H; Sonestedt, E; Wirfält, E	1
Abrahamsson, A; Dabrosin, C; Saarinen, NM	1
Abrahamsson, A; Dabrosin, C; Lindahl, G; Saarinen, N	1
Christensen, J; Johnsen, NF; Knudsen, KE; Olsen, A; Overvad, K; Tjønneland, A	1
Becker, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Kaaks, R; Linseisen, J; Vrieling, A; Zaineddin, AK	1
Patterson, RE	1
Becker, S; Buck, K; Chang-Claude, J; Flesch-Janys, D; Hüsing, A; Kaaks, R; Linseisen, J; Vrieling, A; Zaineddin, AK	1
Abarzua, S; Briese, V; Piechulla, B; Richter, DU; Serikawa, T; Szewczyk, M	1
Boccardo, F; Guglielmini, P; Rubagotti, A	1
Buck, K; Chang-Claude, J; Flesch-Janys, D; Heinz, J; Linseisen, J; Vrieling, A; Zaineddin, AK	1
Adlercreutz, H; Hallmans, G; Hultén, K; Johansson, R; Lenner, P; Winkvist, A	1
Ambrosone, CB; Freudenheim, JL; McCann, SE; Moysich, KB; Shields, PG	1
Arisaka, O; Evans, BA; Miyake, N; Morgan, LD; Morton, MS	1
Grobbee, DE; Keinan-Boker, L; Peeters, PH; van der Schouw, YT	1
Boccardo, F; Lunardi, GL; Petti, AR; Rubagotti, A	1
Chen, J; Thompson, LU	1
Adlercreutz, H; Kilkkinen, A; Pietinen, P; Sankila, R; Vartiainen, E; Virtamo, J; Virtanen, MJ	1
Boccardo, F; Guglielmini, P; Lunardi, G; Murialdo, R; Parodi, M; Rubagotti, A; Schettini, G	1
Adlercreutz, H; Arslan, AA; Kato, I; Koenig, KL; Shore, RE; Toniolo, P; Zeleniuch-Jacquotte, A	1
Knudsen, KE; Loft, S; Møller, S; Olsen, A; Overvad, K; Stripp, C; Thomsen, BL; Tjønneland, A	1
Brooks, JD; Thompson, LU	1
Boccardo, F; Guglielmini, P; Puntoni, M; Rubagotti, A	1
Adlercreutz, H; Bremnes, Y; Gram, IT; Stuedal, A; Ursin, G; Veierød, MB	1
Chang-Claude, J; Linseisen, J; Piller, R	1
Chang-Claude, J; Linseisen, J; Piller, R; Verla-Tebit, E; Wang-Gohrke, S	1
Bergman Jungeström, M; Dabrosin, C; Thompson, LU	1
Bombelli, R; Cosentino, M; Crema, F; Delle Canne, MG; Ferrari, M; Lecchini, S; Legnaro, M; Luini, A; Luzzani, M; Marino, F; Paracchini, S; Rasini, E	1
Airio, M; Mäkelä, S; Saarinen, NM; Smeds, A; Wärri, A	1
Antignac, JP; Dip, R; Gmuender, H; Le Bizec, B; Lenz, S; Naegeli, H	1
Bennetau-Pelissero, C; Carreau, C; Flouriot, G; Potier, M	1
Adlercreutz, H; Dwyer, JT; Fotsis, T; Goldin, BR; Gorbach, SL; Heikkinen, R; Woods, M	1
Adlercreutz, H	2
Ingram, D; Kolybaba, M; Lopez, D; Sanders, K	1
Kurzer, MS; Wang, C	1
Adlercreutz, H; Akhmedkhanov, A; Toniolo, P; Zeleniuch-Jacquotte, A	1
Adlercreut, H; Hallmans, G; Hultén, K; Kilkkinen, A; Mazur, W; Pietinen, P; Stumpf, K	1
Adlercreutz, H; Arts, CJ; den Tonkelaar, I; Keinan-Boker, L; Peeters, PH; Thijssen, JH; Veer, PV	1
Adlercreutz, H; Kataja, V; Männistö, S; Pietinen, P; Stumpf, K; Uusitupa, M	1
Adlercreutz, H; Mousavi, Y	1
Fukuoka, K; Hirano, T; Hosaka, K; Matsumoto, Y; Mitsuhashi, H; Naito, T; Oka, K	1
Calaf, G; Jordan, VC; Koch, R; Murphy, CS; Welshons, WV	1

Reviews

8 review(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and Breast Cancer

Article	Year
Enterolactone concentrations and prognosis after postmenopausal breast cancer: assessment of effect modification and meta-analysis. International journal of cancer, 2014, Aug-15, Volume: 135, Issue:4 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Diet; Disease Progression; Disease-Free Survival; Female; Germany; Humans; Life Style; Lignans; Middle Aged; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors	2014
Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications. Breast cancer (Tokyo, Japan), 2017, Volume: 24, Issue:2 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens; Female; Gastrointestinal Microbiome; Humans; Lignans; Obesity	2017
Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status. International journal of cancer, 2012, Mar-15, Volume: 130, Issue:6 Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Cohort Studies; Estrogens; Humans; Lignans; Logistic Models; Middle Aged; Postmenopause; Progesterone; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Risk Factors	2012
Phytoestrogens and breast cancer risk. Review of the epidemiological evidence. Breast cancer research and treatment, 2003, Volume: 77, Issue:2 Topics: 4-Butyrolactone; Adolescent; Adult; Age Factors; Breast Neoplasms; Case-Control Studies; Climacteric; Diet; Estrogens; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Phytoestrogens; Plant Preparations; Plants; Prospective Studies; Risk	2003
Enterolactone as a risk factor for breast cancer: a review of the published evidence. Clinica chimica acta; international journal of clinical chemistry, 2006, Volume: 365, Issue:1-2 Topics: 4-Butyrolactone; Breast Neoplasms; Diet; Humans; Lignans; Risk Factors	2006
Role of dietary lignans in the reduction of breast cancer risk. Molecular nutrition & food research, 2007, Volume: 51, Issue:7 Topics: 4-Butyrolactone; Animals; Anticarcinogenic Agents; Bacteria; Breast Neoplasms; Cell Division; Diet; Female; Humans; Intestines; Lignans; Mammary Neoplasms, Animal; Plants, Edible; Risk Factors	2007
Food containing phytoestrogens, and breast cancer. BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Edible Grain; Estrogens; Estrogens, Non-Steroidal; Female; Finland; Food; Humans; Isoflavones; Japan; Lignans; Phytoestrogens; Plant Preparations; Pregnancy; Prenatal Exposure Delayed Effects	2000
Phyto-oestrogens and cancer. The Lancet. Oncology, 2002, Volume: 3, Issue:6 Topics: 4-Butyrolactone; Animals; Breast Neoplasms; Diet; Estrogens, Non-Steroidal; Female; Glycine max; Humans; Isoflavones; Lignans; Male; Neoplasms; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Tumor Cells, Cultured	2002

Trials

1 trial(s) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and Breast Cancer

Article	Year
Enterolactone in breast cyst fluid: correlation with EGF and breast cancer risk. Breast cancer research and treatment, 2003, Volume: 79, Issue:1 Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Epidermal Growth Factor; Exudates and Transudates; Female; Fibrocystic Breast Disease; Humans; Lignans; Middle Aged; Odds Ratio; Predictive Value of Tests; Risk Factors; Statistics as Topic	2003

Other Studies

45 other study(ies) available for 2,3-bis(3'-hydroxybenzyl)butyrolactone and Breast Cancer

Article	Year
Proliferative response of ERα-positive breast cancer cells to 10 μM enterolactone, and the associated alteration in the transcriptomic landscape. Gene, 2023, Sep-25, Volume: 881 Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; MCF-7 Cells; Transcriptome	2023
Prognostic associations of circulating phytoestrogens and biomarker changes in long-term survivors of postmenopausal breast cancer. Nutrition and cancer, 2020, Volume: 72, Issue:7 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Female; Genistein; Germany; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies; Survival Analysis; Survivors	2020
Genistein and enterolactone in relation to Ki-67 expression and HER2 status in postmenopausal breast cancer patients. Molecular nutrition & food research, 2017, Volume: 61, Issue:11 Topics: 4-Butyrolactone; Aged; Breast Carcinoma In Situ; Breast Neoplasms; Case-Control Studies; Cell Proliferation; Female; Genistein; Germany; Humans; Isoflavones; Ki-67 Antigen; Lignans; Middle Aged; Neoplasm Grading; Neoplasm Invasiveness; Phytoestrogens; Postmenopause; Prognosis; Receptor, ErbB-2; Tumor Burden	2017
Pre-diagnostic plasma enterolactone concentrations and breast cancer prognosis among postmenopausal women - The Danish Diet, Cancer and Health cohort. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:6 Pt A Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Denmark; Female; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Prognosis	2018
Circulating enterolactone concentrations and prognosis of postmenopausal breast cancer: assessment of mediation by inflammatory markers. International journal of cancer, 2018, 12-01, Volume: 143, Issue:11 Topics: 4-Butyrolactone; Aged; Biomarkers; Breast Neoplasms; Case-Control Studies; Disease-Free Survival; Female; Humans; Inflammation; Lignans; Middle Aged; Postmenopause; Prognosis; Proportional Hazards Models; Prospective Studies	2018
Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women. European journal of clinical nutrition, 2019, Volume: 73, Issue:9 Topics: 4-Butyrolactone; Breast; Breast Neoplasms; Diet; Estrogen Antagonists; Female; Flax; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-18; Interleukin-1beta; Interleukin-8; Lignans; Matrix Metalloproteinase 9; Microdialysis; Middle Aged; Postmenopause; Seeds; Tamoxifen; Tumor Microenvironment	2019
Plasma enterolactone and breast cancer risk in the Nurses' Health Study II. Breast cancer research and treatment, 2013, Volume: 139, Issue:3 Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Cohort Studies; Diet; Estradiol; Female; Humans; Lignans; Multivariate Analysis; Nurses; Premenopause; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; United States; Vegetables	2013
Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer. Nutrition and cancer, 2015, Volume: 67, Issue:8 Topics: 4-Butyrolactone; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclins; Cytoskeleton; Focal Adhesion Kinase 1; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Ki-67 Antigen; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proliferating Cell Nuclear Antigen; RNA, Messenger; S Phase; Signal Transduction	2015
Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. Toxicology and applied pharmacology, 2016, 12-15, Volume: 313 Topics: 4-Butyrolactone; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA Repair; Female; Humans; Lignans; Radiation-Sensitizing Agents	2016
Enterolactone is differently associated with estrogen receptor beta-negative and -positive breast cancer in a Swedish nested case-control study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:11 Topics: 4-Butyrolactone; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Lignans; Linear Models; Microarray Analysis; Middle Aged; Obesity; Prospective Studies; Reproducibility of Results; Risk Assessment; Smoking; Surveys and Questionnaires; Sweden	2008
The protective association of high plasma enterolactone with breast cancer is reasonably robust in women with polymorphisms in the estrogen receptor alpha and beta genes. The Journal of nutrition, 2009, Volume: 139, Issue:5 Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genetic Predisposition to Disease; Humans; Lignans; Middle Aged; Phytoestrogens; Polymorphism, Single Nucleotide; Prospective Studies	2009
Estrogen-induced angiogenic factors derived from stromal and cancer cells are differently regulated by enterolactone and genistein in human breast cancer in vivo. International journal of cancer, 2010, Aug-01, Volume: 127, Issue:3 Topics: 4-Butyrolactone; Angiogenesis Inducing Agents; Animals; Breast Neoplasms; Cell Proliferation; Estrogens; Female; Genistein; Humans; Lignans; Mice; Mice, Nude; Stromal Cells; Vascular Endothelial Growth Factor A	2010
Tamoxifen, flaxseed, and the lignan enterolactone increase stroma- and cancer cell-derived IL-1Ra and decrease tumor angiogenesis in estrogen-dependent breast cancer. Cancer research, 2011, Jan-01, Volume: 71, Issue:1 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Line, Tumor; Estrogen Receptor alpha; Estrogens; Female; Flax; Humans; Immunohistochemistry; Interleukin 1 Receptor Antagonist Protein; Lignans; Macrophages; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Hormone-Dependent; Neovascularization, Pathologic; Stromal Cells; Tamoxifen	2011
Prediagnostic plasma enterolactone levels and mortality among women with breast cancer. Breast cancer research and treatment, 2011, Volume: 128, Issue:3 Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Cohort Studies; Female; Humans; Lignans; Middle Aged; Neoplasm Staging; Prognosis; Receptors, Estrogen; Survival Analysis	2011
Flaxseed and breast cancer: what should we tell our patients? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28 Topics: 4-Butyrolactone; Breast Neoplasms; Female; Humans; Lignans	2011
Serum enterolactone and prognosis of postmenopausal breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Oct-01, Volume: 29, Issue:28 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Female; Humans; Lignans; Middle Aged; Postmenopause; Prognosis	2011
Antiproliferative activity of lignans against the breast carcinoma cell lines MCF 7 and BT 20. Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:4 Topics: 4-Butyrolactone; Anticarcinogenic Agents; Breast Neoplasms; Butylene Glycols; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogens; Female; Furans; Humans; Lignans; Phytoestrogens; Selective Estrogen Receptor Modulators; Tamoxifen	2012
Serum enterolactone levels and mortality outcome in women with early breast cancer: a retrospective cohort study. Breast cancer research and treatment, 2012, Volume: 132, Issue:2 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fluoroimmunoassay; Humans; Italy; Kaplan-Meier Estimate; Lignans; Mastectomy; Middle Aged; Proportional Hazards Models; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Up-Regulation	2012
The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study. Nutrition and cancer, 2012, Volume: 64, Issue:5 Topics: 4-Butyrolactone; Aged; Breast Neoplasms; Carcinoma; Case-Control Studies; Cucurbita; Diet; Dietary Fiber; Female; Germany; Glycine max; Helianthus; Humans; Lignans; Middle Aged; Phytoestrogens; Postmenopause; Risk; Seeds	2012
An incident case-referent study on plasma enterolactone and breast cancer risk. European journal of nutrition, 2002, Volume: 41, Issue:4 Topics: 4-Butyrolactone; Aging; Breast Neoplasms; Cohort Studies; Dietary Fiber; Female; Humans; Lignans; Reference Values; Risk Factors; Surveys and Questionnaires	2002
The risk of breast cancer associated with dietary lignans differs by CYP17 genotype in women. The Journal of nutrition, 2002, Volume: 132, Issue:10 Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Dose-Response Relationship, Drug; Female; Food Analysis; Genotype; Humans; Interviews as Topic; Lignans; Middle Aged; Odds Ratio; Premenopause; Risk Factors; Steroid 17-alpha-Hydroxylase	2002
Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. The Journal of nutrition, 2002, Volume: 132, Issue:10 Topics: 4-Butyrolactone; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Gas Chromatography-Mass Spectrometry; Genistein; Humans; Isoflavones; Japan; Lignans; Male; Middle Aged; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; United Kingdom	2002
Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro. Breast cancer research and treatment, 2003, Volume: 80, Issue:2 Topics: 4-Butyrolactone; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Humans; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Phytotherapy; Receptors, Estrogen; Tamoxifen	2003
Serum enterolactone concentration is not associated with breast cancer risk in a nested case-control study. International journal of cancer, 2004, Jan-10, Volume: 108, Issue:2 Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Cross-Sectional Studies; Estrogens; Female; Finland; Fluoroimmunoassay; Humans; Lignans; Middle Aged; Odds Ratio; Postmenopause; Premenopause; Prospective Studies; Risk Factors	2004
Serum enterolactone levels and the risk of breast cancer in women with palpable cysts. European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:1 Topics: 4-Butyrolactone; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Female; Fibrocystic Breast Disease; Follow-Up Studies; Humans; Lignans; Middle Aged; Regression Analysis; Retrospective Studies; Risk Factors; Serum	2004
Circulating enterolactone and risk of breast cancer: a prospective study in New York. British journal of cancer, 2004, Jul-05, Volume: 91, Issue:1 Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Lignans; Middle Aged; New York; Odds Ratio; Postmenopause; Premenopause; Prospective Studies; Risk Factors	2004
Plasma enterolactone and breast cancer incidence by estrogen receptor status. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:12 Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Cohort Studies; Diet; Female; Humans; Life Style; Lignans; Middle Aged; Postmenopause; Receptors, Estrogen; Risk Factors	2004
Mammalian lignans and genistein decrease the activities of aromatase and 17beta-hydroxysteroid dehydrogenase in MCF-7 cells. The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:5 Topics: 17-Hydroxysteroid Dehydrogenases; 4-Butyrolactone; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Estradiol; Female; Genistein; Humans; Lignans; Mammals; Phytoestrogens	2005
Plasma levels of enterolactone and percentage mammographic density among postmenopausal women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:9 Topics: 4-Butyrolactone; Aged; Biomarkers; Body Mass Index; Breast Neoplasms; Cohort Studies; Female; Humans; Lignans; Mammography; Middle Aged; Postmenopause	2005
Plasma enterolactone and genistein and the risk of premenopausal breast cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2006, Volume: 15, Issue:3 Topics: 4-Butyrolactone; Adult; Breast Neoplasms; Case-Control Studies; Diet; Female; Genistein; Humans; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Premenopause; Risk Factors	2006
CYP17 genotype modifies the association between lignan supply and premenopausal breast cancer risk in humans. The Journal of nutrition, 2006, Volume: 136, Issue:6 Topics: 4-Butyrolactone; Adult; Anticarcinogenic Agents; Breast Neoplasms; Case-Control Studies; Female; Genistein; Genotype; Germany; Humans; Lignans; Logistic Models; Middle Aged; Premenopause; Risk Factors; Steroid 17-alpha-Hydroxylase	2006
Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Feb-01, Volume: 13, Issue:3 Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Endothelium, Vascular; Estradiol; Female; Flax; Humans; Lignans; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Phytoestrogens; Umbilical Veins; Vascular Endothelial Growth Factor A	2007
Estrogenic activity of 7-hydroxymatairesinol potassium acetate (HMR/lignan) from Norway spruce (Picea abies) knots and of its active metabolite enterolactone in MCF-7 cells. Pharmacological research, 2007, Volume: 56, Issue:2 Topics: 4-Butyrolactone; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Lignans; Phytoestrogens; Picea; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tamoxifen	2007
Global gene expression profiles induced by phytoestrogens in human breast cancer cells. Endocrine-related cancer, 2008, Volume: 15, Issue:1 Topics: 4-Butyrolactone; Animals; Biomarkers, Tumor; Breast Neoplasms; Cattle; Estradiol; Estrogen Receptor beta; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genistein; Humans; Isoflavones; Lignans; Milk; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Phytoestrogens; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Soy Milk; Tumor Cells, Cultured	2008
Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERalpha transcriptional activation in human breast cancer cells. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 110, Issue:1-2 Topics: 4-Butyrolactone; Animals; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Estrogen Receptor alpha; Flavonoids; HeLa Cells; Humans; Lignans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Phenols; Phytoestrogens; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; Transcriptional Activation	2008
Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Lancet (London, England), 1982, Dec-11, Volume: 2, Issue:8311 Topics: 4-Butyrolactone; Aged; Benzopyrans; Breast Neoplasms; Butylene Glycols; Chromans; Diet; Diet, Vegetarian; Dietary Fiber; Energy Intake; Equol; Female; Furans; Humans; Isoflavones; Lignans; Menopause; Menstruation; Middle Aged; Plant Extracts	1982
Does fiber-rich food containing animal lignan precursors protect against both colon and breast cancer? An extension of the "fiber hypothesis". Gastroenterology, 1984, Volume: 86, Issue:4 Topics: 4-Butyrolactone; Breast Neoplasms; Chemical Phenomena; Chemistry; Colonic Neoplasms; Dietary Fiber; Estrogens; Female; Humans; Lignans; Male; Plant Extracts	1984
Case-control study of phyto-oestrogens and breast cancer. Lancet (London, England), 1997, Oct-04, Volume: 350, Issue:9083 Topics: 4-Butyrolactone; Breast Neoplasms; Case-Control Studies; Chromans; Diet; Equol; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Lignans; Middle Aged; Phytoestrogens; Plant Preparations; Plants; Risk Factors	1997
Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors. Nutrition and cancer, 1998, Volume: 31, Issue:2 Topics: 4-Butyrolactone; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chamomile; Coumestrol; DNA, Neoplasm; Epidermal Growth Factor; Estradiol; Estrogens, Non-Steroidal; Female; Flavonoids; Genistein; Humans; Insulin; Isoflavones; Lignans; Luteolin; Oils, Volatile; Phytoestrogens; Plant Preparations; Plants, Medicinal; Tamoxifen; Tumor Cells, Cultured	1998
Reliability of serum measurements of lignans and isoflavonoid phytoestrogens over a two-year period. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:10 Topics: 4-Butyrolactone; Adult; Age Factors; Aged; Bias; Breast Neoplasms; Chromans; Equol; Feasibility Studies; Female; Genistein; Humans; Isoflavones; Lignans; Middle Aged; New York City; Pilot Projects; Postmenopause; Premenopause; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Time Factors	1998
Urinary phytoestrogens and postmenopausal breast cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:3 Topics: 4-Butyrolactone; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Cohort Studies; Confidence Intervals; Estrogens, Non-Steroidal; Female; Fluoroimmunoassay; Genetic Predisposition to Disease; Genistein; Humans; Isoflavones; Lignans; Logistic Models; Mass Screening; Middle Aged; Netherlands; Odds Ratio; Phytoestrogens; Plant Preparations; Postmenopause; Predictive Value of Tests; Reference Values; Risk Assessment; Risk Factors; Sensitivity and Specificity	2001
Serum enterolactone and risk of breast cancer: a case-control study in eastern Finland. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:4 Topics: 4-Butyrolactone; Adult; Aged; Breast Neoplasms; Case-Control Studies; Diet; Dietary Fiber; Female; Finland; Humans; Lignans; Middle Aged; Odds Ratio; Plant Growth Regulators; Postmenopause; Premenopause; Preventive Medicine; Risk Factors; Vitamin E	2001
Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. The Journal of steroid biochemistry and molecular biology, 1992, Volume: 41, Issue:3-8 Topics: 4-Butyrolactone; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Kinetics; Lignans; Tumor Cells, Cultured	1992
Antiproliferative activity of mammalian lignan derivatives against the human breast carcinoma cell line, ZR-75-1. Cancer investigation, 1990, Volume: 8, Issue:6 Topics: 4-Butyrolactone; Adenosine Triphosphatases; Animals; Benzyl Compounds; Breast Neoplasms; Butylene Glycols; Cell Division; Cell Line; Dogs; Dose-Response Relationship, Drug; Fluorouracil; Humans; Kidney Cortex; Lethal Dose 50; Lignans; Ouabain	1990
Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol. Breast cancer research and treatment, 1987, Volume: 10, Issue:2 Topics: 4-Butyrolactone; Benzopyrans; Breast Neoplasms; Butylene Glycols; Cell Division; Chromans; Equol; Estrogens; Female; Furans; Humans; Isoflavones; Lignans; Receptors, Progesterone; Tumor Cells, Cultured	1987