Compounds > 2'3'-didehydro-2'3'-dideoxyadenosine
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2'3'-didehydro-2'3'-dideoxyadenosine and HIV

2'3'-didehydro-2'3'-dideoxyadenosine has been researched along with HIV in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R1
Eriksson, S; Gosselin, G; Imbach, JL; Maury, G; Pélicano, H; Pierra, C1
Aquaro, S; Balzarini, J; De Clercq, E; Heijtink, R; Kruining, J; McGuigan, C; Naesens, L; Pannecouque, C; Perno, CF; Wedgwood, O; Witvrouw, M1

Other Studies

4 other study(ies) available for 2'3'-didehydro-2'3'-dideoxyadenosine and HIV

ArticleYear
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:8

    Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication

1987
Synthesis and anti-HIV activity of various 2'- and 3'-substituted 2',3'-dideoxyadenosines: a structure-activity analysis.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; HIV; Structure-Activity Relationship

1987
Enzymatic properties of the unnatural beta-L-enantiomers of 2',3'-dideoxyadenosine and 2',3'-didehydro-2',3'-dideoxyadenosine.
    Journal of medicinal chemistry, 1997, Nov-21, Volume: 40, Issue:24

    Topics: Adenosine Deaminase; Adenosine Kinase; Animals; Anti-HIV Agents; Antiviral Agents; Cattle; Deoxycytidine Kinase; Dideoxyadenosine; Drug Stability; Hepatitis B virus; HIV; Humans; Purine-Nucleoside Phosphorylase; Stereoisomerism; Structure-Activity Relationship

1997
Conversion of 2',3'-dideoxyadenosine (ddA) and 2',3'-didehydro-2',3'-dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus.
    FEBS letters, 1997, Jun-30, Volume: 410, Issue:2-3

    Topics: Adenosine Monophosphate; Alanine; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cells, Cultured; Dideoxyadenosine; Hepatitis B virus; HIV; Humans; Leukocytes, Mononuclear; Macrophages; Molecular Structure; Moloney murine sarcoma virus; Simian Immunodeficiency Virus; Transfection; Tumor Cells, Cultured

1997