Page last updated: 2024-08-21

2,2-dimethylbutyric acid and Anemia, Cooley's

2,2-dimethylbutyric acid has been researched along with Anemia, Cooley's in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Foong, WC; Ho, JJ; Lau, DS; Loh, CK1
Berenson, R; Boosalis, M; Chaneim, N; Fucharoen, S; Inati, A; Koussa, S; Perrine, SP; Siritanaratku, N; Taher, A; Thein, SL; Wargin, WC1
Abboud, MR; Ataga, KI; Buchanan, GR; El-Beshlawy, A; Ghalie, RG; Inati, A; Kutlar, A; Perrine, SP; Reid, ME; Smith, H; Taher, AT1
Abbas, HA; Abi Nasr, T; Chui, DH; Ghalie, RG; Inati, A; Kahale, M; Koussa, S; Perrine, SP; Taher, AT1
Boosalis, MS; Chaneiam, N; Chui, DH; Fuchareon, S; Ghalie, RG; Patthamalai, P; Perrine, SP1

Reviews

1 review(s) available for 2,2-dimethylbutyric acid and Anemia, Cooley's

ArticleYear
Foetal haemoglobin inducers for reducing blood transfusion in non-transfusion-dependent beta-thalassaemias.
    The Cochrane database of systematic reviews, 2023, 01-13, Volume: 1

    Topics: beta-Thalassemia; Blood Transfusion; Fetal Hemoglobin; Humans; Hydroxyurea; Resveratrol

2023

Trials

4 trial(s) available for 2,2-dimethylbutyric acid and Anemia, Cooley's

ArticleYear
A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia.
    British journal of haematology, 2013, Volume: 161, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; beta-Thalassemia; Butyrates; Female; Fetal Hemoglobin; Gene Expression Regulation; Humans; Male; Middle Aged; Splenectomy; Treatment Outcome; Young Adult

2013
A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.
    American journal of hematology, 2013, Volume: 88, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; beta-Thalassemia; Butyrates; Child; Cohort Studies; Dose-Response Relationship, Drug; Female; Fetal Hemoglobin; Gastritis; Hematinics; Heterozygote; Humans; Hydroxyurea; Incidence; Male; Middle Aged; Patient Dropouts; Promoter Regions, Genetic; Sickle Cell Trait; Up-Regulation; Young Adult

2013
A phase 2 study of HQK-1001, an oral fetal haemoglobin inducer, in β-thalassaemia intermedia.
    British journal of haematology, 2014, Volume: 164, Issue:3

    Topics: Adolescent; Adult; beta-Thalassemia; Butyrates; Female; Fetal Hemoglobin; Humans; Male; Middle Aged; Young Adult

2014
A phase 2 trial of HQK-1001 in HbE-β thalassemia demonstrates HbF induction and reduced anemia.
    Blood, 2014, Mar-20, Volume: 123, Issue:12

    Topics: Adult; beta-Thalassemia; Butyrates; Female; Fetal Hemoglobin; Hemoglobin E; Hemoglobins; Humans; Male; Young Adult

2014