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2,2,3,3-tetramethylcyclopropane carboxamide and Absence Seizure

2,2,3,3-tetramethylcyclopropane carboxamide has been researched along with Absence Seizure in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bialer, M; Sobol, E; Yagen, B1
Bialer, M; Isoherranen, N; Levy, RH; White, HS; Woodhead, JH; Yagen, B1
Bialer, M; Shimshoni, JA; Yagen, B1
Barton, ME; Bennett, GD; Bialer, M; Finnell, RH; Isoherranen, N; White, HS; Wilcox, KS; Woodhead, JH; Yagen, B1

Other Studies

4 other study(ies) available for 2,2,3,3-tetramethylcyclopropane carboxamide and Absence Seizure

ArticleYear
Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Journal of medicinal chemistry, 2004, Aug-12, Volume: 47, Issue:17

    Topics: Animals; Anticonvulsants; Convulsants; Cyclopropanes; Electroshock; Mice; Pentylenetetrazole; Polyunsaturated Alkamides; Rats; Seizures; Species Specificity; Structure-Activity Relationship; Urea; Valproic Acid

2004
Metabolism of a new antiepileptic drug, N-methyl-tetramethylcyclopropanecarboxamide, and anticonvulsant activity of its metabolites.
    Epilepsy research, 2004, Volume: 58, Issue:1

    Topics: Amides; Animals; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Behavior, Animal; Biotransformation; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cyclopropanes; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Electroshock; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; In Vitro Techniques; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Pentylenetetrazole; Seizures; Valproic Acid

2004
Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Administration, Oral; Amides; Animals; Anticonvulsants; Cyclopropanes; Electroshock; Isoxazoles; Mice; Motor Activity; Rats; Seizures; Sulfonamides; Urea; Valproic Acid; Zonisamide

2008
Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
    Epilepsia, 2002, Volume: 43, Issue:2

    Topics: Acoustic Stimulation; Administration, Oral; Amides; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Convulsants; Cyclopropanes; Electrophysiology; Electroshock; Epilepsy; Injections, Intraperitoneal; Mice; Mice, Inbred Strains; Mutagenicity Tests; Neural Tube Defects; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures

2002