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2,2'-dipyridyl and Neoplasms

2,2'-dipyridyl has been researched along with Neoplasms in 24 studies

2,2'-Dipyridyl: A reagent used for the determination of iron.
2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"It was also found that the anticancer activity of the poly(bpy) ligands could be controlled by the complexation (anticancer activity is turned OFF) and decomplexation (anticancer activity is turned ON) with biorelevant metal cations."1.91Design and Synthesis of Poly(2,2'-Bipyridyl) Ligands for Induction of Cell Death in Cancer Cells: Control of Anticancer Activity by Complexation/Decomplexation with Biorelevant Metal Cations. ( Aoki, S; Balachandran, C; Hirose, M; Hisamatsu, Y; Tanaka, T; Yamada, Y; Yokoi, K; Zhu, JJ, 2023)
"CaeA also affects paclitaxel-resistant cancer cells and synergizes the effect with paclitaxel in reducing cancer cell colony formation rate."1.72Characterization of Caerulomycin A as a dual-targeting anticancer agent. ( Han, Y; Sun, W; Tong, L; Wu, S, 2022)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.17)18.2507
2000's2 (8.33)29.6817
2010's15 (62.50)24.3611
2020's6 (25.00)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Tong, L1
Sun, W1
Wu, S1
Han, Y1
Gurgul, I2
Mazuryk, O2
Stachyra, K1
Olszanecki, R1
Lekka, M2
Łomzik, M2
Suzenet, F2
Gros, PC2
Brindell, M2
Janczy-Cempa, E1
Zhu, Z2
Wei, L2
Yadav, AK2
Fan, Z2
Kumar, A2
Miao, M2
Banerjee, S2
Huang, H3
Lyons, MJ1
Ehrhardt, C1
Walsh, JJ1
Balachandran, C1
Hirose, M1
Tanaka, T1
Zhu, JJ1
Yokoi, K1
Hisamatsu, Y1
Yamada, Y1
Aoki, S1
Boulsourani, Z1
Katsamakas, S1
Geromichalos, GD1
Psycharis, V1
Raptopoulou, CP1
Hadjipavlou-Litina, D1
Yiannaki, E1
Dendrinou-Samara, C1
Nishiguchi, GA1
Rico, A1
Tanner, H1
Aversa, RJ1
Taft, BR1
Subramanian, S1
Setti, L1
Burger, MT1
Wan, L1
Tamez, V1
Smith, A1
Lou, Y1
Barsanti, PA1
Appleton, BA1
Mamo, M1
Tandeske, L1
Dix, I1
Tellew, JE1
Huang, S1
Mathews Griner, LA1
Cooke, VG1
Van Abbema, A1
Merritt, H1
Ma, S1
Gampa, K1
Feng, F1
Yuan, J1
Wang, Y2
Haling, JR1
Vaziri, S1
Hekmat-Nejad, M1
Jansen, JM1
Polyakov, V1
Zang, R1
Sethuraman, V1
Amiri, P1
Singh, M1
Lees, E1
Shao, W1
Stuart, DD1
Dillon, MP1
Ramurthy, S1
Luengo, A1
Fernández-Moreira, V1
Marzo, I1
Gimeno, MC1
Zhang, F1
Lin, QY1
Hu, WL1
Song, WJ1
Shen, ST1
Gui, P1
Lin, GJ1
Jiang, GB1
Xie, YY1
Huang, HL1
Liang, ZH1
Liu, YJ1
Liao, X1
Lu, J1
Ying, P1
Zhao, P1
Bai, Y1
Li, W1
Liu, M1
Zhang, P1
Chen, H1
Ji, L1
Chao, H1
Liu, SH1
Zhu, JW1
Xu, HH1
Liu, YM1
Liang, JB1
Zhang, GQ1
Cao, DH1
Lin, YY1
Wu, Y1
Guo, QF1
Blanco, NG1
Maldonado, CR1
Mareque-Rivas, JC1
Vo, V1
Kabuloglu-Karayusuf, ZG1
Carper, SW1
Bennett, BL1
Evilia, C1
Gao, E2
Zhu, M2
Liu, L2
Huang, Y1
Wang, L1
Shi, C1
Zhang, W2
Sun, Y2
Buchtík, R1
Trávníček, Z1
Vančo, J1
Herchel, R1
Dvořák, Z1
Gabbiani, C1
Casini, A1
Kelter, G1
Cocco, F1
Cinellu, MA1
Fiebig, HH1
Messori, L1
Guan, F1
Gao, X1
Wang, C1
Liu, J2
Sun, RW1
Leung, CH1
Lok, CN1
Che, CM1
Tan, L1
Shen, J1
Zeng, L1
Jin, L1
Weng, C1
Nocentini, G1
Barzi, A1

Reviews

2 reviews available for 2,2'-dipyridyl and Neoplasms

ArticleYear
Orellanine: From Fungal Origin to a Potential Future Cancer Treatment.
    Journal of natural products, 2023, Jun-23, Volume: 86, Issue:6

    Topics: 2,2'-Dipyridyl; Agaricales; Humans; Mycotoxins; Neoplasms

2023
Antitumor activity of 2,2'-bipyridyl-6-carbothioamide: a ribonucleotide reductase inhibitor.
    General pharmacology, 1997, Volume: 29, Issue:5

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Chelating Agents; Enzyme Inhibitors; Humans; Neoplas

1997

Other Studies

22 other studies available for 2,2'-dipyridyl and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Characterization of Caerulomycin A as a dual-targeting anticancer agent.
    European journal of pharmacology, 2022, May-05, Volume: 922

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening

2022
Impact of Polypyridyl Ru Complexes on Angiogenesis-Contribution to Their Antimetastatic Activity.
    International journal of molecular sciences, 2022, Jul-12, Volume: 23, Issue:14

    Topics: 2,2'-Dipyridyl; Coordination Complexes; Endothelial Cells; Humans; Ligands; Neoplasms; Phenanthrolin

2022
Inhibition of Metastasis by Polypyridyl Ru(II) Complexes through Modification of Cancer Cell Adhesion -
    Journal of medicinal chemistry, 2022, 08-11, Volume: 65, Issue:15

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Cell Adhesion; Coordination Complexes; Humans; Ligands; Neopl

2022
Cyanine-Functionalized 2,2'-Bipyridine Compounds for Photocatalytic Cancer Therapy.
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Coordination Complexes; NAD; Neoplasms; Oxidation-Reduction

2023
Cyanine-Functionalized 2,2'-Bipyridine Compounds for Photocatalytic Cancer Therapy.
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Coordination Complexes; NAD; Neoplasms; Oxidation-Reduction

2023
Cyanine-Functionalized 2,2'-Bipyridine Compounds for Photocatalytic Cancer Therapy.
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Coordination Complexes; NAD; Neoplasms; Oxidation-Reduction

2023
Cyanine-Functionalized 2,2'-Bipyridine Compounds for Photocatalytic Cancer Therapy.
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Coordination Complexes; NAD; Neoplasms; Oxidation-Reduction

2023
Design and Synthesis of Poly(2,2'-Bipyridyl) Ligands for Induction of Cell Death in Cancer Cells: Control of Anticancer Activity by Complexation/Decomplexation with Biorelevant Metal Cations.
    Inorganic chemistry, 2023, Sep-11, Volume: 62, Issue:36

    Topics: 2,2'-Dipyridyl; Cations; Cell Death; Chelating Agents; Humans; Ligands; Metals; Neoplasms; Poly A

2023
Synthesis, structure elucidation and biological evaluation of triple bridged dinuclear copper(II) complexes as anticancer and antioxidant/anti-inflammatory agents.
    Materials science & engineering. C, Materials for biological applications, 2017, Jul-01, Volume: 76

    Topics: 2,2'-Dipyridyl; Anti-Inflammatory Agents; Copper; Crystallography, X-Ray; Humans; Molecular Structur

2017
Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Benzamides; Crystallography, X-Ray; Dogs; Drug Desig

2017
Trackable Metallodrugs Combining Luminescent Re(I) and Bioactive Au(I) Fragments.
    Inorganic chemistry, 2017, Dec-18, Volume: 56, Issue:24

    Topics: 2,2'-Dipyridyl; A549 Cells; Antineoplastic Agents; Cell Proliferation; Coordination Complexes; Gold;

2017
Interaction with biomacromolecules and antiproliferative activities of Mn(II), Ni(II), Zn(II) complexes of demethylcantharate and 2,2'-bipyridine.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 110

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cantharidin; Cattle; Cell Line, Tumor; Cell Prolifer

2013
Cytotoxicity, apoptosis, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential, and Western blotting analysis of ruthenium(II) complexes.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:8

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Checkpoints; Cell Li

2013
DNA binding, antitumor activities, and hydroxyl radical scavenging properties of novel oxovanadium (IV) complexes with substituted isoniazid.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:8

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Cycle; Cell Line, Tumor; Coo

2013
Comparison between polypyridyl and cyclometalated ruthenium(II) complexes: anticancer activities against 2D and 3D cancer models.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2015, Jan-07, Volume: 21, Issue:2

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA; Drug Screening Assays,

2015
Protein-binding, cytotoxicity in vitro and cell cycle arrest of ruthenium(II) polypyridyl complexes.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2016, May-15, Volume: 161

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Coordina

2016
Effective photoreduction of a Pt(IV) complex with quantum dots: a feasible new light-induced method of releasing anticancer Pt(II) drugs.
    Chemical communications (Cambridge, England), 2009, Sep-21, Issue:35

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Cadmium Compounds; Electron Transport; Light; Neoplasms; Orga

2009
Novel 4,4'-diether-2,2'-bipyridine cisplatin analogues are more effective than cisplatin at inducing apoptosis in cancer cell lines.
    Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3

    Topics: 2,2'-Dipyridyl; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Screening Ass

2010
Impact of the carbon chain length of novel palladium(II) complexes on interaction with DNA and cytotoxic activity.
    Inorganic chemistry, 2010, Apr-05, Volume: 49, Issue:7

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cry

2010
Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(II) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone.
    Dalton transactions (Cambridge, England : 2003), 2011, Oct-07, Volume: 40, Issue:37

    Topics: 2,2'-Dipyridyl; 4-Quinolones; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Copper; Crys

2011
Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability.
    Metallomics : integrated biometal science, 2011, Volume: 3, Issue:12

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays,

2011
Novel palladium(II) complexes containing a sulfur ligand: structure and biological activity on HeLa cells.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2012, Volume: 17, Issue:2

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Apoptosis; DNA; HeLa Cells; Humans; Intercalating Agents; Lig

2012
Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes.
    Chemical communications (Cambridge, England), 2012, Jan-07, Volume: 48, Issue:2

    Topics: 2,2'-Dipyridyl; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans;

2012
Spectral characteristics, DNA-binding and cytotoxicity of two functional Ru(II) mixed-ligand complexes.
    Dalton transactions (Cambridge, England : 2003), 2012, Apr-21, Volume: 41, Issue:15

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cell Survival; Coordination Complexes; DNA;

2012