2,2'-dipyridyl and Leukemia P388 studies

2,2'-dipyridyl and Leukemia P388

2,2'-dipyridyl has been researched along with Leukemia P388 in 12 studies

2,2'-Dipyridyl: A reagent used for the determination of iron.
2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.

Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.

Research Excerpts

Excerpt	Relevance	Reference
"The cytotoxicity of hydroxyurea in combination with 2."	1.28	Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase. ( Barzi, A; Franchetti, P; Nocentini, G, 1990)
" Of these, only 2,2'-bipyridyl-6-carbothioamide (1a) showed antitumor activity at relatively high dosage levels."	1.26	N-N-S* tridentate ligand system as potential antitumor agents. ( Antonini, I; Claudi, F; Cristalli, G; Franchetti, P; Grifantini, M; Martelli, S, 1981)

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (50.00)	18.7374
1990's	5 (41.67)	18.2507
2000's	1 (8.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

6 (50.00)

18.7374

1990's

5 (41.67)

18.2507

2000's

1 (8.33)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Antonini, I	2
Claudi, F	1
Cristalli, G	3
Franchetti, P	5
Grifantini, M	3
Martelli, S	2
Paul, AK	1
Mansuri-Torshizi, H	3
Srivastava, TS	4
Chavan, SJ	2
Chitnis, MP	4
Yoo, J	1
Sohn, YS	1
Do, Y	1
Ghadimy, S	1
Akbarzadeh, N	1
Nocentini, G	2
Federici, F	1
Armellini, R	1
Barzi, A	2
Jain, N	1
Mital, R	1
Ray, KS	1
Bhattacharya, RK	1
Satyamoorthy, K	1
Filippeschi, S	1
Ripa, S	1
Puthraya, KH	1
Amonkar, AJ	1
Adwankar, MK	1

Studies

Antonini, I

Claudi, F

Cristalli, G

Franchetti, P

Grifantini, M

Martelli, S

Paul, AK

Mansuri-Torshizi, H

Srivastava, TS

Chavan, SJ

Chitnis, MP

Yoo, J

Sohn, YS

Do, Y

Ghadimy, S

Akbarzadeh, N

Nocentini, G

Federici, F

Armellini, R

Barzi, A

Jain, N

Mital, R

Ray, KS

Bhattacharya, RK

Satyamoorthy, K

Filippeschi, S

Ripa, S

Puthraya, KH

Amonkar, AJ

Adwankar, MK

Other Studies

12 other studies available for 2,2'-dipyridyl and Leukemia P388

Article	Year
N-N-S* tridentate ligand system as potential antitumor agents. Journal of medicinal chemistry, 1981, Volume: 24, Issue:10 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Leukemia P388; Ligands; Mice; Mice, Inbred Strains;	1981
Some potential antitumor 2,2'-dipyridylamine Pt(II)/Pd(II) complexes with amino acids: their synthesis, spectroscopy, DNA binding, and cytotoxic studies. Journal of inorganic biochemistry, 1993, Apr-01, Volume: 50, Issue:1 Topics: 2,2'-Dipyridyl; Alanine; Amino Acids; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Glycin	1993
Synthesis, structures and antitumor activity of the first crown ester-linked bipyridyl platinum complexes. Journal of inorganic biochemistry, 1999, Volume: 73, Issue:3 Topics: 2,2'-Dipyridyl; Animals; Carboplatin; Cisplatin; Crystallography, X-Ray; Drug Screening Assays, Anti	1999
Synthesis, characterization, DNA binding and cytotoxic studies of platinum(II) and palladium(II) complexes of the 2,2'-bipyridine and an anion of 1,1-cyclobutanedicarboxylic acid. Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:12 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; DNA; Kinetics; Leukemia P388; Magnetic Resonance Spe	2001
Cytotoxicity and DNA binding studies of several platinum (II) and palladium (II) complexes of the 2,2'-bipyridine and an anion of 2-pyridinecarboxylic/2-pyrazinecarboxylic acid. Journal of inorganic biochemistry, 1992, Oct-01, Volume: 48, Issue:1 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Leukemia P388; Palladium; Pl	1992
Isolation of two cellular lines resistant to ribonucleotide reductase inhibitors to investigate the inhibitory activity of 2,2'-bipyridyl-6-carbothioamide. Anti-cancer drugs, 1990, Volume: 1, Issue:2 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cell Cycle; Drug Resistance; Drug Screening Assays,	1990
Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase. Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Chelating Agents; Data Interpretation, Statistical;	1990
Synthesis, spectroscopic, mutagenic, and cytotoxicity studies of some mixed-ligand platinum(II) complexes of 2,2'-bipyridine and amino acids. Journal of inorganic biochemistry, 1987, Volume: 31, Issue:1 Topics: 2,2'-Dipyridyl; Amino Acids; Animals; Antineoplastic Agents; Indicators and Reagents; Leukemia P388;	1987
Hyperthermia blocks reversibility of hydroxyurea and bipyridine induced synergistic inhibition of DNA biosynthesis in P388 murine leukemia cells. Neoplasma, 1988, Volume: 35, Issue:2 Topics: 2,2'-Dipyridyl; Animals; DNA Replication; Drug Synergism; Hot Temperature; Hydroxyurea; Kinetics; Le	1988
2,2'-Bipyridyl-6-carbothioamide derivatives as potential antitumor agents. Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:5 Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia P388; Mice;	1986
2,2'-Bipyridyl-6-carboxamidoximes with potential antitumor and antimicrobial properties. Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:7 Topics: 2,2'-Dipyridyl; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacter	1986
Some mixed-ligand palladium(II) complexes of 2,2'-bipyridine and amino acids as potential anticancer agents. Journal of inorganic biochemistry, 1985, Volume: 25, Issue:3 Topics: 2,2'-Dipyridyl; Amino Acids; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chemical Phen	1985

Article

Year

N*-N*-S* tridentate ligand system as potential antitumor agents.

Journal of medicinal chemistry, 1981, Volume: 24, Issue:10

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Leukemia P388; Ligands; Mice; Mice, Inbred Strains;

1981

Some potential antitumor 2,2'-dipyridylamine Pt(II)/Pd(II) complexes with amino acids: their synthesis, spectroscopy, DNA binding, and cytotoxic studies.

Journal of inorganic biochemistry, 1993, Apr-01, Volume: 50, Issue:1

Topics: 2,2'-Dipyridyl; Alanine; Amino Acids; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Glycin

1993

Synthesis, structures and antitumor activity of the first crown ester-linked bipyridyl platinum complexes.

Journal of inorganic biochemistry, 1999, Volume: 73, Issue:3

Topics: 2,2'-Dipyridyl; Animals; Carboplatin; Cisplatin; Crystallography, X-Ray; Drug Screening Assays, Anti

1999

Synthesis, characterization, DNA binding and cytotoxic studies of platinum(II) and palladium(II) complexes of the 2,2'-bipyridine and an anion of 1,1-cyclobutanedicarboxylic acid.

Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:12

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; DNA; Kinetics; Leukemia P388; Magnetic Resonance Spe

2001

Cytotoxicity and DNA binding studies of several platinum (II) and palladium (II) complexes of the 2,2'-bipyridine and an anion of 2-pyridinecarboxylic/2-pyrazinecarboxylic acid.

Journal of inorganic biochemistry, 1992, Oct-01, Volume: 48, Issue:1

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Leukemia P388; Palladium; Pl

1992

Isolation of two cellular lines resistant to ribonucleotide reductase inhibitors to investigate the inhibitory activity of 2,2'-bipyridyl-6-carbothioamide.

Anti-cancer drugs, 1990, Volume: 1, Issue:2

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Cell Cycle; Drug Resistance; Drug Screening Assays,

1990

Implications and problems in analysing cytotoxic activity of hydroxyurea in combination with a potential inhibitor of ribonucleotide reductase.

Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:5

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Chelating Agents; Data Interpretation, Statistical;

1990

Synthesis, spectroscopic, mutagenic, and cytotoxicity studies of some mixed-ligand platinum(II) complexes of 2,2'-bipyridine and amino acids.

Journal of inorganic biochemistry, 1987, Volume: 31, Issue:1

Topics: 2,2'-Dipyridyl; Amino Acids; Animals; Antineoplastic Agents; Indicators and Reagents; Leukemia P388;

1987

Hyperthermia blocks reversibility of hydroxyurea and bipyridine induced synergistic inhibition of DNA biosynthesis in P388 murine leukemia cells.

Neoplasma, 1988, Volume: 35, Issue:2

Topics: 2,2'-Dipyridyl; Animals; DNA Replication; Drug Synergism; Hot Temperature; Hydroxyurea; Kinetics; Le

1988

2,2'-Bipyridyl-6-carbothioamide derivatives as potential antitumor agents.

Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:5

Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Leukemia P388; Mice;

1986

2,2'-Bipyridyl-6-carboxamidoximes with potential antitumor and antimicrobial properties.

Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:7

Topics: 2,2'-Dipyridyl; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacter

1986

Some mixed-ligand palladium(II) complexes of 2,2'-bipyridine and amino acids as potential anticancer agents.

Journal of inorganic biochemistry, 1985, Volume: 25, Issue:3

Topics: 2,2'-Dipyridyl; Amino Acids; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Chemical Phen

1985