2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid has been researched along with Cognition-Disorders* in 2 studies
2 other study(ies) available for 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and Cognition-Disorders
| Article | Year |
|---|---|
Studies of the Anti-amnesic Effects and Mechanisms of Single and Combined Use of Donepezil and Ginkgo Ketoester Tablet on Scopolamine-Induced Memory Impairment in Mice.
Topics: Acetylcholine; Acetylcholinesterase; Amnesia; Animals; Benzothiazoles; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Drug Therapy, Combination; Ginkgo biloba; Ginkgolides; Ligands; Malondialdehyde; Memory Disorders; Mice, Inbred ICR; Molecular Docking Simulation; Picrates; Plant Extracts; Receptor, trkB; Scopolamine; Sulfonic Acids; Superoxide Dismutase; Tablets | 2019 |
2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice.
In this study, the protective effect of sweet potato extract against hydrogen peroxide-induced oxidative stress and cytotoxicity on the pheochromocytoma cell line (PC12) was investigated. The active component of the sweet potato extract was purified and determined to be 2,4-di-tert-butylphenol. The antioxidant capacity of 2,4-di-tert-butylphenol was measured by using 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical. To examine the effects of 2,4-di-tert-butylphenol on amyloid-beta peptide (Aβ1₁₋₄₂)-induced learning and memory impairment in mice, in vivo behavioral tests were performed. Administration of 2,4-di-tert-butylphenol increased alternation behavior in mice injected with Aβ₁₋₄₂. These results suggest that sweet potato extract could be protective against Aβ-induced neurotoxicity, possibly due to the antioxidative capacity of its constituent, 2,4-di-tert-butylphenol. Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Cognition Disorders; Ipomoea batatas; Lythraceae; Male; Memory Disorders; Mice; Mice, Inbred ICR; Oxidative Stress; PC12 Cells; Phenols; Phytotherapy; Plant Extracts; Rats; Sulfonic Acids | 2013 |