2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid has been researched along with Carbon-Tetrachloride-Poisoning* in 2 studies
2 other study(ies) available for 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and Carbon-Tetrachloride-Poisoning
| Article | Year |
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Potential of long-term dietary administration of rosemary in improving the antioxidant status of rat tissues following carbon tetrachloride intoxication.
In this study, 24 Wistar rats were allocated to 4 groups of 6 animals each. Groups 1 and 2 were fed a basal diet, while groups 3 and 4 were fed the basal diet supplemented further with ground rosemary at 1% level. Following 6-weeks feeding, groups 2 and 4 were injected 1 ml CCl(4)/kg bw and after six hours all animals were sacrificed. Results showed that feeding rosemary before CCl(4) treatment resulted in decline (P<0.05) of the increased aspartate transaminase, alanine transaminase and alkaline phosphatase activities and increase (P<0.05) of the reduced cholesterol and triacylglycerols in serum. It also decreased (P<0.05) lipid peroxidation and increased (P<0.05) the reduced hydroxyl anion radical and hydrogen peroxide scavenging activities in serum, liver, kidney and heart tissues. In addition, it increased (P<0.05) the reduced ABTS radical cation and the superoxide anion scavenging activities in all tissues except in heart and in kidney and heart tissues, respectively. These results suggest that dietary rosemary has the potential to become a promising functional food component. Topics: Animals; Antioxidants; Benzothiazoles; Carbon Tetrachloride Poisoning; Chromans; Diet; Electron Transport; Female; Free Radicals; Kidney; Ledum; Lipid Peroxidation; Liver; Malondialdehyde; Myocardium; NADPH-Ferrihemoprotein Reductase; Phenols; Plant Leaves; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfonic Acids | 2010 |
Antioxidant and hepatoprotective activity of ethanol extract of Arachniodes exilis (Hance) Ching.
The study was aimed to investigate the ethanol extract of Arachniodes exilis for the antioxidant and hepatoprotective activity.. Antioxidant activity was evaluated by different assays, including reducing power, lipid peroxidation, 2, 2'-diphenyl-1-picrylhydrazyl (DPPH), 2, 2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS), superoxide anion, hydroxyl radicals and hydrogen peroxide. The hepatoprotective activity of ethanol extract was studied on mice liver damage induced by CCL(4) by monitoring biochemical parameters.. The extract showed potent activities on reducing power, lipid peroxide, DPPH, ABTS, superoxide anion, hydroxyl radical and hydrogen peroxide. And oral administration of Arachniodes exilis at different doses resulted in significant improvement on the levels of glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, malondialchehyche and superoxidedismutase.. The results indicate that this plant possesses potential antioxidant and hepatoprotective properties and has therapeutic potential for the treatment of liver diseases. Topics: Animals; Antioxidants; Benzothiazoles; Biphenyl Compounds; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Dryopteridaceae; Female; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Male; Mice; Phytotherapy; Picrates; Plant Extracts; Protective Agents; Rhizome; Sulfonic Acids; Superoxides; Thiazoles | 2010 |