2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and Body-Weight

2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid has been researched along with Body-Weight* in 4 studies

Trials

1 trial(s) available for 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and Body-Weight

ArticleYear
Tomato juice consumption improves blood antioxidative biomarkers in overweight and obese females.
    Clinical nutrition (Edinburgh, Scotland), 2015, Volume: 34, Issue:5

    A few studies reported the beneficial effects of tomato juice on oxidative stress status. However, supporting data in obese subjects is scarce. This study aimed to determine the effects of tomato juice consumption on erythrocyte antioxidant enzymes, namely, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), plasma total antioxidant capacity (TAC), and serum malondialdehyde (MDA) in overweight and obese females.. A randomized controlled clinical trial was conducted on 64 overweight or obese (BMI = 25 kg/m(2) or higher) female students of Shiraz University of Medical Sciences. Subjects randomly received tomato juice (n = 32, 330 ml/d) or water (n = 28) for 20 days. Daily dietary intake, anthropometric measures and blood antioxidant parameters were determined at the beginning and after 20 days intervention period.. Plasma TAC and erythrocyte antioxidant enzymes increased and serum MDA decreased in the intervention group compared with baseline and with the control group (p < 0.05). In the intervention group, similar results were found in overweight, but not in obese, subjects.. Our results suggest that tomato juice reduces oxidative stress in overweight (and possibly obese) females and, therefore, may prevent from obesity related diseases and promote health.

    Topics: Adult; Antioxidants; Benzothiazoles; Biomarkers; Body Mass Index; Body Weight; Catalase; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Energy Intake; Erythrocytes; Female; Fruit and Vegetable Juices; Glutathione Peroxidase; Humans; Malondialdehyde; Nutrition Assessment; Obesity; Overweight; Oxidative Stress; Solanum lycopersicum; Sulfonic Acids; Superoxide Dismutase; Young Adult

2015

Other Studies

3 other study(ies) available for 2-2--azino-di-(3-ethylbenzothiazoline)-6-sulfonic-acid and Body-Weight

ArticleYear
Curative Effect of Catechin Isolated from
    Molecules (Basel, Switzerland), 2020, Dec-30, Volume: 26, Issue:1

    In this study, catechin (CTN) isolated from

    Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Benzothiazoles; Biphenyl Compounds; Blood Glucose; Body Weight; Catechin; Diabetes Mellitus, Experimental; Elaeagnaceae; Free Radical Scavengers; Free Radicals; Fruit; Glyburide; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; In Vitro Techniques; Inhibitory Concentration 50; Kidney; Lipid Peroxides; Lipids; Malondialdehyde; Phenol; Picrates; Plant Extracts; Rats; Rats, Sprague-Dawley; Streptozocin; Sulfonic Acids

2020
Effects of Choline on Meat Quality and Intramuscular Fat in Intrauterine Growth Retardation Pigs.
    PloS one, 2015, Volume: 10, Issue:6

    The aim of this study was to investigate the effects of choline supplementation on intramuscular fat (IMF) and lipid oxidation in IUGR pigs. Twelve normal body weight (NBW) and twelve intrauterine growth retardation (IUGR) newborn piglets were collected and distributed into 4 treatments (Normal: N, Normal+Choline: N+C, IUGR: I, and IUGR+Choline: I+C) with 6 piglets in each treatment. At 23 d of age, NBW and IUGR pigs were fed basal or choline supplemented diets. The results showed that the IUGR pigs had significantly lower (P<0.05) BW as compared with the NBW pigs at 23 d, 73 d, and 120 d of age, however, there was a slight decreased (P>0.05) in BW of IUGR pigs than the NBW pigs at 200 d. Compared with the NBW pigs, pH of meat longissimus dorsi muscle was significantly lower (P<0.05), and the meat color was improved in IUGR pigs. The malondialdehyde (MDA) levels were significantly decreased (P<0.05), while triglyceride (TG) and IMF contents were significantly higher (P<0.05) in the IUGR pigs than the NBW pigs. IUGR up-regulated the mRNA gene expression of fatty acid synthetase (FAS) and acetyl-CoA carboxylase (ACC). Dietary choline significantly increased (P<0.05) the BW at 120d of age, however, significantly decreased (P<0.05) the TG and IMF contents in both IUGR and NBW pigs. FAS and sterol regulatory element-binding proteins 1 (SREBP1) mRNA gene expressions were increased (P<0.05) while the muscle-carnitine palmityl transferase (M-CPT) and peroxisome proliferators-activated receptorγ (PPARγ) mRNA (P<0.05) gene expressions were decreased in the muscles of the IUGR pigs by choline supplementation. Furthermore, choline supplementation significantly increased (P<0.05) the MDA content as well as the O2•¯ scavenging activity in meat of IUGR pigs. The results suggested that IUGR pigs showed a permanent stunting effect on the growth performance, increased fat deposition and oxidative stress in muscles. However, dietary supplementation of choline improved the fat deposition via enhancing the lipogenesis and reducing the lipolysis.

    Topics: Animal Feed; Animals; Benzothiazoles; Biphenyl Compounds; Body Weight; Choline; Dietary Supplements; Fats; Fetal Growth Retardation; Food Quality; Malondialdehyde; Muscles; Picrates; Red Meat; Sulfonic Acids; Sus scrofa

2015
Therapeutic window for cinnamophilin following oxygen-glucose deprivation and transient focal cerebral ischemia.
    Experimental neurology, 2009, Volume: 217, Issue:1

    Cinnamophilin (CINN, (8R, 8'S)-4, 4'-dihydroxy-3, 3'-dimethoxy-7-oxo-8, 8'-neolignan) protects against ischemic stroke in mice. While some anti-oxidative effects of CINN have been characterized, its therapeutic window and molecular basis for neuroprotection remain unclear. We evaluated antioxidant and anti-inflammatory properties and therapeutic window of CINN against brain ischemia using a panel of in vitro and in vivo assays. Data from lipid peroxidation and radical scavenging assays showed that CINN was a robust antioxidant and radical scavenger. CINN effectively inhibited the production of tumor necrosis factor alpha (TNF-alpha), nitrite/nitrate, interleukin-6 (IL-6) in lipopolysaccharide (LPS)-stimulated RAW 264.7 and BV2 cells (P<0.05, respectively). Relative to controls, CINN, administrated at 80 mg/kg, 2, 4, or 6 h postinsult, but not 12 h, significantly reduced brain infarction by 34-43% (P<0.05) and improved neurobehavioral outcome (P<0.05) following transient focal cerebral ischemia in rats. CINN (10-30 microM) also significantly reduced oxygen-glucose deprivation-induced neuronal damage (P<0.05) in rat organotypic hippocampal slices, even when it was administrated 2, 4, or 6 h postinsult. Together, CINN protects against ischemic brain damage with a therapeutic window up to 6 h in vivo and in vitro, which may, at least in part, be attributed by its direct antioxidant and anti-inflammatory effects.

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Benzothiazoles; Body Weight; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Guaiacol; Hippocampus; Hypoxia; Interleukin-6; Ischemic Attack, Transient; Lignans; Lipid Peroxidation; Microglia; Nitrates; Nitrites; Organ Culture Techniques; Peroxidase; Phenethylamines; Polysaccharides; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sulfonic Acids; Time Factors; Tumor Necrosis Factor-alpha

2009