2,2',2''-trichlorotriethylamine has been researched along with Hodgkin Disease in 4 studies
2,2',2''-trichlorotriethylamine: RN given refers to parent cpd; structure
Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-three patients with advanced Hodgkin's disease, most of them previously treated, received 8 to 16 courses of modified MOPP regimens (nitrogen mustard replaced by trichlormethine in arm A, with addition of vinblastine to the 4-drug regimen in arm B, and alternation of three drugs--trichlormethine, vincristine, and prednisone--with probably non-cross resistant two drugs--vinblastine and procarbazine in arm C)." | 1.28 | Treatment of advanced Hodgkin's disease with modified MOPP regimens. A long-term observation. ( Bohunický, L; Cerný, V; Gyárfás, J; Koza, I; Mardiak, J; Svancárová, L, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TEWES, H | 1 |
| Goodman, LS | 1 |
| Wintrobe, MM | 1 |
| Dameshek, W | 1 |
| Goodman, MJ | 1 |
| Gilman, A | 1 |
| McLennan, MT | 1 |
| Klener, P | 1 |
| Donner, L | 1 |
| Koza, I | 1 |
| Bohunický, L | 1 |
| Svancárová, L | 1 |
| Mardiak, J | 1 |
| Gyárfás, J | 1 |
| Cerný, V | 1 |
4 other studies available for 2,2',2''-trichlorotriethylamine and Hodgkin Disease
| Article | Year |
|---|---|
[Roentgen resistant lymphogranulomatosis treated with trichlorotriethylamine hydrochloride, with special reference to following modifications in the hemopoietic system].
Topics: Hematopoietic System; Hodgkin Disease; Mechlorethamine; Nitrogen Mustard Compounds; Sarcoidosis | 1950 |
Landmark article Sept. 21, 1946: Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders.
Topics: History, 20th Century; Hodgkin Disease; Humans; Leukemia; Lymphoma, Non-Hodgkin; Mechlorethamine; Ne | 1984 |
Trichlortriethylamine (TS-160 Spofa) in combination chemotherapy of malignant lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymp | 1975 |
Treatment of advanced Hodgkin's disease with modified MOPP regimens. A long-term observation.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Hu | 1989 |