2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid has been researched along with Adrenocortical Carcinoma in 5 studies
*Adrenocortical Carcinoma: A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bach de Assis, C; Cavalcante de Figueiredo, B; Cruz Bonk, B; de Almeida Veiga, A; de Toledo Nogueira, B; Lada Degaut Pontes, F; Mera de Souza, L; Regina Rocha Martins, L; Rita Corso, C; Stadler, G | 1 |
| Allegra, S; Berruti, A; Carrella, S; Cusato, J; D'Avolio, A; Daffara, FC; De Francia, S; De Martino, F; Di Carlo, F; Ferrero, A; Piccione, FM; Pirro, E; Tampellini, M; Terzolo, M | 1 |
| Al Ghuzlan, A; Baudin, E; Brailly-Tabard, S; Hescot, S; Lombès, M; Paci, A; Seck, A; Slama, A; Trabado, S; Viengchareun, S; Young, J | 1 |
| Fassnacht, M; Heinz, W; Kendl, S; Klinker, H; Kroiss, M; Lapa, C; Plonné, D; Ronchi, CL; Sbiera, S; Schirbel, A; Schirmer, D; Zink, M | 1 |
| Allolio, B; Baudin, E; Berruti, A; Chadarevian, R; Daffara, F; den Hartigh, J; Fassnacht, M; Haak, HR; Hermsen, IG; Houterman, S; Leboulleux, S; Schlumberger, M; Terzolo, M | 1 |
5 other study(ies) available for 2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid and Adrenocortical Carcinoma
| Article | Year |
|---|---|
Two-dimensional chromatography for enantiomeric analysis of mitotane and its metabolite o,p'-DDA in patients with adrenocortical carcinoma indicates enantioselective metabolism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Chromatography, High Pressure Liquid; Humans; Mitotane; Stereoisomerism | 2023 |
Circannual variation of mitotane and its metabolites plasma levels in patients with adrenocortical carcinoma.
Topics: Adipose Tissue; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mitotane; Seasons; Sex Factors; Time Factors; Young Adult | 2017 |
The lack of antitumor effects of o,p'DDA excludes its role as an active metabolite of mitotane for adrenocortical carcinoma treatment.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Apoptosis; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex IV; Enzyme Activation; Humans; Mitochondrial Turnover; Mitotane; Oxidative Stress; Steroids | 2014 |
Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Chyle; Chylomicrons; Cohort Studies; Endoplasmic Reticulum Stress; Female; Gastrointestinal Absorption; Humans; Lipoproteins; Lipoproteins, HDL2; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Mitotane | 2016 |
Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Female; Humans; Male; Middle Aged; Mitotane; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity | 2011 |