2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid has been researched along with Adrenal Cortex Cancer in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bach de Assis, C; Cavalcante de Figueiredo, B; Cruz Bonk, B; de Almeida Veiga, A; de Toledo Nogueira, B; Lada Degaut Pontes, F; Mera de Souza, L; Regina Rocha Martins, L; Rita Corso, C; Stadler, G | 1 |
| Allegra, S; Berruti, A; Carrella, S; Cusato, J; D'Avolio, A; Daffara, FC; De Francia, S; De Martino, F; Di Carlo, F; Ferrero, A; Piccione, FM; Pirro, E; Tampellini, M; Terzolo, M | 1 |
| Al Ghuzlan, A; Baudin, E; Brailly-Tabard, S; Hescot, S; Lombès, M; Paci, A; Seck, A; Slama, A; Trabado, S; Viengchareun, S; Young, J | 1 |
| Fassnacht, M; Heinz, W; Kendl, S; Klinker, H; Kroiss, M; Lapa, C; Plonné, D; Ronchi, CL; Sbiera, S; Schirbel, A; Schirmer, D; Zink, M | 1 |
| Allolio, B; Baudin, E; Berruti, A; Chadarevian, R; Daffara, F; den Hartigh, J; Fassnacht, M; Haak, HR; Hermsen, IG; Houterman, S; Leboulleux, S; Schlumberger, M; Terzolo, M | 1 |
| Andersen, A; Kasperlik-Zaluska, AA; Warren, DJ | 1 |
1 trial(s) available for 2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Determination of mitotane (o,p-DDD) and its metabolites o,p-DDA and o,p-DDE in plasma by high-performance liquid chromatography.
Topics: Adrenal Cortex Neoplasms; Adrenergic Agents; Adult; Aged; Antineoplastic Agents, Hormonal; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Linear Models; Male; Middle Aged; Mitotane | 1999 |
5 other study(ies) available for 2,2-(2-chlorophenyl-4'-chlorophenyl)acetic acid and Adrenal Cortex Cancer
| Article | Year |
|---|---|
Two-dimensional chromatography for enantiomeric analysis of mitotane and its metabolite o,p'-DDA in patients with adrenocortical carcinoma indicates enantioselective metabolism.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Chromatography, High Pressure Liquid; Humans; Mitotane; Stereoisomerism | 2023 |
Circannual variation of mitotane and its metabolites plasma levels in patients with adrenocortical carcinoma.
Topics: Adipose Tissue; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Agents, Hormonal; Chemotherapy, Adjuvant; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Mitotane; Seasons; Sex Factors; Time Factors; Young Adult | 2017 |
The lack of antitumor effects of o,p'DDA excludes its role as an active metabolite of mitotane for adrenocortical carcinoma treatment.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Apoptosis; Cell Line, Tumor; Cell Proliferation; Electron Transport Complex IV; Enzyme Activation; Humans; Mitochondrial Turnover; Mitotane; Oxidative Stress; Steroids | 2014 |
Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Chyle; Chylomicrons; Cohort Studies; Endoplasmic Reticulum Stress; Female; Gastrointestinal Absorption; Humans; Lipoproteins; Lipoproteins, HDL2; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Mitotane | 2016 |
Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Female; Humans; Male; Middle Aged; Mitotane; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity | 2011 |