2'-o-methylcytidine has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
*Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, H; Isobe, T; Izumikawa, K; Nakayama, H; Nobe, Y; Sato, K; Simpson, RJ; Takahashi, N; Taoka, M; Yamauchi, Y | 1 |
1 other study(ies) available for 2'-o-methylcytidine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs.
Topics: Amyotrophic Lateral Sclerosis; Cell Nucleolus; Coiled Bodies; Cytidine; DNA-Binding Proteins; HeLa Cells; Humans; Molecular Chaperones; Proteins; Ribonucleoproteins, Small Nuclear; RNA, Guide, Kinetoplastida; RNA, Small Nuclear; Telomerase | 2019 |