Page last updated: 2024-09-04

2'-fluorothymidine and Hepatitis B, Chronic

2'-fluorothymidine has been researched along with Hepatitis B, Chronic in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.56)	18.2507
2000's	37 (57.81)	29.6817
2010's	26 (40.63)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
He, L; Jiang, Y; Liu, X; Wang, X; Yang, Z; Zhang, S; Zhao, Y	1
Tak, WY	1
Fung, J; Lai, CL; Seto, WK; Yuen, MF	1
Cho, HC; Cho, JY; Choi, MS; Gwak, GY; Koh, KC; Lee, JH; Paik, SW; Paik, YH; Sohn, W; Yoo, BC	1
Jang, JY; Kim, BH; Kim, JW; Lee, CK; Shim, JJ	1
Berg, T; van Bömmel, F	1
Hwang, JH; Jang, ES; Jeong, SH; Kim, JW; Kim, N; Lee, DH; Lee, SS; Min, BY; Park, YS; Seong, MH; Shin, CM; Sohn, HR; Song, JC	1
Ahn, SH; Chong, Y; Kang, HS; Kim, BK; Kim, DH; Kim, KH; Lee, AR; Park, ES; Park, S; Park, YK; Rhee, JK; Shin, GC; Yang, SI	1
Ahn, SH; Cho, EY; Hwang, SG; Jeong, SH; Jung, YK; Kim, HS; Kim, IH; Kim, JH; Kim, JW; Lee, JI; Lee, JM; Lee, JW; Lee, SH; Park, SJ; Seo, YS; Suh, SJ; Yim, HJ	1
Cheong, JY	1
Yim, HJ	1
Asselah, T; Lada, O; Marcellin, P; Moucari, R	1
Cheong, JY; Cho, SW; Choi, YW; Kang, CJ; Kim, DH; Kim, MJ; Koh, KH	1
Choi, DJ; Hwang, YJ; Kim, GH; Kim, JH; Kim, YS; Kwon, OS	1
Zarski, JP	1
Jo, HY; Kim, DS; Kim, HS; Kim, SY; Lee, CH; Lee, DK; Park, MS; Seok, JI	1
Choe, WH; Kim, BK; Kim, KH; Ko, SY; Kwon, SY; Lee, CH	1
Lee, KS	1
Eun, JR; Hwang, JS; Jang, BK; Kim, BS; Lee, CH; Lee, HJ; Suh, JI	1
Anderson, DL	1
Choe, WH; Kim, BK; Ko, SY; Kwon, SY; Lee, CH; Lim, SD; Oh, J; Rhee, KH; Seo, TH	1
Fleischer, RD; Lok, AS	1
Bae, WK; Kim, HJ; Kim, KA; Kim, MH; Kim, NH; Lee, HW; Lee, JS; Moon, YS; Yun, SG	1
Bae, CH; Bae, M; Baik, SK; Choi, JH; Choi, SK; Chun, GJ; Gu, C; Gu, ES; Jang, DS; Kang, SS; Kim, HS; Kim, JH; Kim, JS; Lee, EJ; Lee, JS; Lee, KS; Lee, SH; Moon, SK; Park, ET; Park, NH; Park, SI; Shin, JW; Yu, BJ	1
Ahn, SH; Cho, ES; Choe, WH; Choi, HS; Kim, BK; Kim, KH; Ko, SY; Kwon, SY; Lee, CH; Park, ES; Park, YK; Shin, GC	1
Hwang, JH; Jang, JH; Jeong, SH; Kim, HS; Kim, JW; Kim, N; Lee, DH; Lee, SH; Myung, HJ; Park, YS	1
Byun, KS; Jung, ES; Jung, YK; Kim, JH; Lee, HS; Seo, YS; Um, SH; Yeon, JE; Yim, HJ	1
Cho, YK; Jeon, WK; Kim, BI; Kim, HJ; Park, DI; Park, JH; Sohn, CI	1
Choi, CS; Kim, DG; Kim, HC; Kim, IH; Kim, SH; Kim, SW; Lee, S; Lee, SO; Lee, ST	1
Cho, CM; Jeon, SW; Jung, MK; Kweon, YO; Park, JY; Park, SY; Sohn, YK; Tak, WY	1
Lau, GK; Leung, N	1
Bae, SH; Baek, YH; Han, SY; Lee, SW	1
Chae, HB; Kang, YW; Kim, AN; Kim, HS; Kim, SB; Kim, SH; Lee, BS; Lee, HIe; Lee, HY; Lee, SH; Lee, TH; Nam, KW; Song, IH; Yang, HW	1
Choi, YY; Hwang, HS; Jang, SJ; Kim, YH; Lee, JA; Lee, MH; Paik, SS; Yoo, DH	1
Suzuki, F	2
Jang, TS; Kim, HY; Kwon, HD; Lee, HS; Lim, J	1
Choi, BS; Choi, SR; Chung, BH; Hong, YA; Kim, YS; Park, CW; Park, HS; Sun, IO; Yang, CW	1
Chae, HB; Kang, HY; Kang, YW; Kim, AN; Kim, HS; Kim, SB; Kim, SH; Kim, YM; Lee, BS; Lee, ES; Lee, HIe; Lee, HY; Lee, SH; Lee, TH; Noh, R; Song, IH; Yang, HY	1
Choi, DJ; Jung, YK; Kim, JH; Kim, YS; Kwon, OS; Lee, JJ; Lee, JW; Lee, YJ	1
Cote, PJ; Gerin, JL; Korba, BE; Menne, S; Roneker, CA; Tennant, BC	2
Jamard, C; Martin, P; Rimsky, L; Schorr, O; Seignères, B; Trépo, C; Werle, B; Zoulim, F	1
Buti, M; Esteban, R	1
Hadziyannis, SJ; Papatheodoridis, GV	1
Avci, A; Erhardt, A; Häussinger, D; Heintges, T; Lörke, J; Sagir, A	1
Lok, AS	1
Blum, MR; Bronowicki, JP; Conway, B; Lau, GK; Lee, HS; Marcellin, P; Mommeja-Marin, H; Mondou, E; Rousseau, F; Sacks, SL; Sereni, D; Snow, A; Sorbel, J; Trepo, C; Yoo, BC	1
Aldrich, CE; Cullen, JM; Jilbert, AR; Mason, WS; Miller, D; Saputelli, J; Seeger, C; Zhu, Y	1
Baldwin, BH; Cote, PJ; Gerin, JL; Korba, BE; Menne, S; Tennant, BC; Toshkov, I; Wells, FV	1
Zoulim, F	1
Hui, CK; Lau, GK	1
Casey, J; Chu, CK; Cote, PJ; Gerin, JL; Hornbuckle, WE; Korba, BE; Tennant, BC; Toshkov, IA	1
Byun, KS; Chung, YH; Han, JY; Lee, HS; Lee, JH; Lee, K; Paik, SW; Yoo, BC; Yoo, HW; Yoo, K	1
Chan, S; Kotzev, IA; Krastev, Z; Lim, SG; Mechkov, G; Mondou, E; Ng, TM; Rousseau, F; Snow, A; Sorbel, J	1
Furman, PA; Korba, BE; Otto, MJ	1
Byun, KS; Cho, M; Cho, SH; Choi, JY; Choi, SK; Chon, CY; Chung, YH; Han, BH; Han, JY; Hwang, JS; Hwang, SG; Jeong, SH; Kim, BI; Kim, DG; Kim, HC; Kim, JH; Kim, TH; Kim, YS; Kweon, YO; Lee, HJ; Lee, HS; Lee, HY; Lee, KS; Lee, MS; Lee, YJ; Lee, YS; Paik, SW; Park, JW; Ryu, SH; Um, SH; Yang, JM; Yoo, BC; Yoo, HW; Yoo, K	1
Byun, KS; Chung, YH; Han, JY; Lee, HS; Lee, KS; Paik, SW; Yoo, BC; Yoo, HW; Yoo, K	1
Byun, KS; Cho, M; Cho, SH; Choi, JY; Choi, SK; Chon, CY; Chung, YH; Han, BH; Han, JY; Hwang, JS; Hwang, SG; Jeong, SH; Kim, BI; Kim, DG; Kim, HC; Kim, JH; Kim, TH; Kim, YS; Koh, KC; Kweon, YO; Lee, HJ; Lee, HS; Lee, HY; Lee, KS; Lee, MS; Lee, YJ; Lee, YS; Park, JW; Ryu, SH; Um, SH; Yang, JM; Yoo, BC; Yoo, HW; Yoo, K	1
Cote, PJ; Gerin, JL; Menne, S; Tennant, BC	1
Bozdayi, AM; Karaaslan, H; Karatayli, E; Karayalçin, S; Kayhan, H; Sahin, F; Türkyilmaz, AR; Yurdaydin, C	1
Blum, MR; Hann, HW; Lau, GK; Leung, N; Lim, SG; Marcellin, P; Mommeja-Marin, H; Moxham, C; Rousseau, F; Snow, A; Sorbel, J; Trepo, C	1
Boudinot, FD; Cheng, YC; Choi, Y; Chu, CK; Cote, PJ; Gerin, JL; Hong, JH; Korba, BE; Peek, SF; Tennant, BC	1
Baldwin, BH; Chu, CK; Cote, PJ; Gerin, JL; Hornbuckle, WE; Jacob, JR; Korba, BE; Peek, SF; Tennant, BC; Toshkov, IA; Wells, FV	1

Reviews

16 review(s) available for 2'-fluorothymidine and Hepatitis B, Chronic

Article	Year
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis. Disease markers, 2017, Volume: 2017 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Organophosphonates; Retrospective Studies; Survival Analysis; Telbivudine; Tenofovir; Thymidine	2017
Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment. Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3 Topics: Acidosis, Lactic; Adenine; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis B, Chronic; Humans; Kidney Diseases; Male; Muscular Diseases; Nervous System Diseases; Nucleosides; Nucleotides; Organophosphonates; Pharmacovigilance; Pregnancy; Telbivudine; Tenofovir; Thymidine	2014
[Management of chronic hepatitis B in treatment-naive patients]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 51, Issue:6 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Korea; Lamivudine; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Recombinant Proteins	2008
[Management of antiviral-resistant chronic hepatitis B virus infection]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 51, Issue:6 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome	2008
Clevudine: a promising therapy for the treatment of chronic hepatitis B. Expert opinion on investigational drugs, 2008, Volume: 17, Issue:12 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Drug Evaluation, Preclinical; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Nucleosides	2008
Clevudine for hepatitis B. Drugs of today (Barcelona, Spain : 1998), 2009, Volume: 45, Issue:5 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Hepatitis B, Chronic; Humans	2009
Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B. Journal of hepatology, 2009, Volume: 51, Issue:4 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Drug Discovery; Early Termination of Clinical Trials; Hepatitis B, Chronic; Humans; Lamivudine; Mitochondrial Myopathies; Muscular Diseases; Nervous System Diseases; Nucleosides; Nucleotides; Pyrimidinones; Republic of Korea; Telbivudine; Thymidine	2009
[New drugs of treatment of patients with chronic hepatitis B]. Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70, Issue:4 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2012
Entecavir, FTC, L-FMAU, LdT and others. Journal of hepatology, 2003, Volume: 39 Suppl 1 Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B, Chronic; Humans; Randomized Controlled Trials as Topic; Thymidine	2003
Treatment of HBeAg negative chronic hepatitis B with new drugs (adefovir and others). Journal of hepatology, 2003, Volume: 39 Suppl 1 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates	2003
[New approaches in the treatment of hepatitis B]. Deutsche medizinische Wochenschrift (1946), 2004, May-21, Volume: 129, Issue:21 Topics: 2-Aminopurine; Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Contraindications; Deoxycytidine; Emtricitabine; Famciclovir; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Neoplasms; Organophosphonates; Organophosphorus Compounds; Polyethylene Glycols; Prodrugs; Prognosis; Recombinant Proteins; Tenofovir; Zalcitabine	2004
New treatment of chronic hepatitis B. Seminars in liver disease, 2004, Volume: 24 Suppl 1 Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome	2004
Combination of nucleoside analogues in the treatment of chronic hepatitis B virus infection: lesson from experimental models. The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:5 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Disease Models, Animal; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides	2005
Clevudine for the treatment of chronic hepatitis B virus infection. Expert opinion on investigational drugs, 2005, Volume: 14, Issue:10 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Drug Evaluation, Preclinical; Hepatitis B virus; Hepatitis B, Chronic; Humans	2005
Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo. Expert review of anti-infective therapy, 2006, Volume: 4, Issue:4 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Hepatitis B virus; Hepatitis B, Chronic; Humans	2006
Preclinical investigation of L-FMAU as an anti-hepatitis B virus agent. Antiviral therapy, 1998, Volume: 3, Issue:Suppl 3 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Biological Availability; Cell Line; Deoxycytidine Kinase; Drug Evaluation, Preclinical; Ducks; Hepadnaviridae Infections; Hepatitis B virus; Hepatitis B Virus, Duck; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Lactic Acid; Lethal Dose 50; Marmota; Mice; Phosphorylation; Rats; Thymidine Kinase	1998

Trials

14 trial(s) available for 2'-fluorothymidine and Hepatitis B, Chronic

Article	Year
Clinical and virological responses to clevudine therapy in chronic hepatitis B patients: results at 1 year of an open-labelled prospective study. Antiviral therapy, 2009, Volume: 14, Issue:4 Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Longitudinal Studies; Male	2009
[Long-term clevudine therapy in nucleos(t)ide-naïve and lamivudine-experienced patients with hepatitis B virus-related chronic liver diseases]. The Korean journal of hepatology, 2009, Volume: 15, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; RNA-Directed DNA Polymerase	2009
Clevudine demonstrates potent antiviral activity in naïve chronic hepatitis B patients. Intervirology, 2010, Volume: 53, Issue:2 Topics: Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Plasma; Treatment Failure; Treatment Outcome; Viral Load	2010
Treatment outcomes of clevudine versus lamivudine at week 48 in naïve patients with HBeAg positive chronic hepatitis B. Journal of Korean medical science, 2010, Volume: 25, Issue:5 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Treatment Outcome	2010
Forty-eight weeks treatment with clevudine 30 mg qd versus lamivudine 100 mg qd for chronic hepatitis B infection: a double-blind randomized study. The Korean journal of hepatology, 2010, Volume: 16, Issue:3 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged	2010
[Treatment efficacy of clevudine, entecavir and lamivudine in treatment-naive patients with HBeAg-positive chronic hepatitis B]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2010, Volume: 56, Issue:6 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Treatment Outcome	2010
Mathematical modeling of triphasic viral dynamics in patients with HBeAg-positive chronic hepatitis B showing response to 24-week clevudine therapy. PloS one, 2012, Volume: 7, Issue:11 Topics: Adolescent; Adult; Antiviral Agents; Arabinofuranosyluracil; Computer Simulation; DNA, Viral; Female; Hepatitis B Antigens; Hepatitis B, Chronic; Hepatocytes; Humans; Immune System; Least-Squares Analysis; Male; Middle Aged; Models, Theoretical; Regression Analysis; Time Factors; Viral Load	2012
A phase II dose-escalating trial of clevudine in patients with chronic hepatitis B. Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:1 Topics: Adult; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Arabinofuranosyluracil; Area Under Curve; DNA, Viral; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gene Dosage; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Predictive Value of Tests; Treatment Outcome	2004
A 12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B. Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:5 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Time Factors	2006
Randomized, double-blind study of emtricitabine (FTC) plus clevudine versus FTC alone in treatment of chronic hepatitis B. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:5 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Amylases; Antiviral Agents; Arabinofuranosyluracil; Aspartate Aminotransferases; Bicarbonates; Bilirubin; Blood Glucose; Creatine Kinase; Deoxycytidine; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrolytes; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Randomized Controlled Trials as Topic; Serum Albumin	2006
Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B. Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:5 Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Double-Blind Method; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Placebos	2007
Clevudine therapy for 24 weeks further reduced serum hepatitis B virus DNA levels and increased ALT normalization rates without emergence of viral breakthrough than 12 weeks of clevudine therapy. Intervirology, 2007, Volume: 50, Issue:4 Topics: Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Treatment Outcome	2007
Clevudine is highly efficacious in hepatitis B e antigen-negative chronic hepatitis B with durable off-therapy viral suppression. Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:4 Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Time Factors	2007
Clinical trial: a phase II, randomized study evaluating the safety, pharmacokinetics and anti-viral activity of clevudine for 12 weeks in patients with chronic hepatitis B. Alimentary pharmacology & therapeutics, 2008, Volume: 27, Issue:12 Topics: Adolescent; Adult; Antibodies, Viral; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Genotype; Hepatitis B, Chronic; Humans; Male; Middle Aged; Treatment Outcome	2008

Other Studies

34 other study(ies) available for 2'-fluorothymidine and Hepatitis B, Chronic

Article	Year
[Antiviral effect of entecavir switching therapy in chronic hepatitis B patients with clevudine-associated myopathy]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Jan-25, Volume: 61, Issue:1 Topics: Antiviral Agents; Arabinofuranosyluracil; Female; Guanine; Hepatitis B, Chronic; Humans; Male; Muscular Diseases	2013
Patients with chronic hepatitis B treated with oral antiviral therapy retain a higher risk for HCC compared with patients with inactive stage disease. Gut, 2014, Volume: 63, Issue:12 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Kaplan-Meier Estimate; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Outcome Assessment, Health Care; Patient Acuity; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Time	2014
Oral antiviral therapy improves the diagnostic accuracy of alpha-fetoprotein levels in patients with chronic hepatitis B. Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:9 Topics: Administration, Oral; Adult; Aged; alpha-Fetoproteins; Antiviral Agents; Arabinofuranosyluracil; Biomarkers; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Time Factors	2014
Antiviral therapy of chronic hepatitis B. Intervirology, 2014, Volume: 57, Issue:3-4 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication	2014
Off-treatment virologic relapse and outcomes of re-treatment in chronic hepatitis B patients who achieved complete viral suppression with oral nucleos(t)ide analogs. BMC infectious diseases, 2014, Aug-13, Volume: 14 Topics: Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Recurrence; Retrospective Studies; Treatment Outcome	2014
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance. PloS one, 2015, Volume: 10, Issue:8 Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; Cell Line, Tumor; Drug Resistance, Multiple, Viral; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Microbial Sensitivity Tests; Models, Molecular; Organophosphonates; Tenofovir; Virus Replication	2015
Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study. Gut and liver, 2017, Jan-15, Volume: 11, Issue:1 Topics: Adenine; Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Cohort Studies; Disease Management; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Viral Load	2017
[Development of clevudine resistance after switching from lamivudine in a patient with chronic hepatitis B]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 52, Issue:5 Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; Base Sequence; DNA, Viral; Drug Resistance, Multiple, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Organophosphonates; Reverse Transcriptase Inhibitors	2008
Early development of clevudine resistance during clevudine therapy in a patient with chronic hepatitis B who received prior lamivudine therapy. Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:6 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Sequence Analysis, DNA	2009
[New molecules in the treatment of chronic hepatitis B]. Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:5 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Organophosphonates; Tenofovir	2009
Long-term therapy with clevudine for chronic hepatitis B can be associated with myopathy characterized by depletion of mitochondrial DNA. Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:6 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; DNA, Mitochondrial; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mitochondrial Myopathies; Time Factors	2009
[Clevudine therapy in patients with chronic hepatitis B]. The Korean journal of hepatology, 2009, Volume: 15, Issue:2 Topics: Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Lamivudine; Practice Guidelines as Topic	2009
Clevudine myopathy in patients with chronic hepatitis B. Journal of hepatology, 2009, Volume: 51, Issue:4 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; DNA, Viral; Electromyography; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Middle Aged; Muscular Diseases	2009
[Efficacy of 48-week clevudine therapy for chronic hepatitis B]. The Korean journal of hepatology, 2009, Volume: 15, Issue:3 Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Retrospective Studies; Treatment Outcome	2009
Identification and characterization of clevudine-resistant mutants of hepatitis B virus isolated from chronic hepatitis B patients. Journal of virology, 2010, Volume: 84, Issue:9 Topics: Adult; Amino Acid Substitution; Antiviral Agents; Arabinofuranosyluracil; DNA Mutational Analysis; Drug Resistance, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mutation, Missense; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Serum; Treatment Failure; Viral Proteins	2010
Clevudine for chronic hepatitis B: antiviral response, predictors of response, and development of myopathy. Journal of viral hepatitis, 2011, Volume: 18, Issue:2 Topics: Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Muscular Diseases; Prognosis; Republic of Korea; Retrospective Studies; Treatment Outcome; Viral Load	2011
Virologic and biochemical responses to clevudine in patients with chronic HBV infection-associated cirrhosis: data at week 48. Journal of viral hepatitis, 2011, Volume: 18, Issue:4 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Female; Hepatitis B, Chronic; Humans; Korea; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Treatment Outcome; Viral Load	2011
Comparison between clevudine and entecavir treatment for antiviral-naïve patients with chronic hepatitis B. Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:6 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Biomarkers; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Muscular Diseases; Republic of Korea; Retrospective Studies; Time Factors; Treatment Outcome; Viral Load; Virus Replication	2010
Clinical, biochemical, and pathological characteristics of clevudine-associated myopathy. Journal of hepatology, 2010, Volume: 53, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Arabinofuranosyluracil; Biopsy; Creatine Kinase; Dose-Response Relationship, Drug; Exercise Tolerance; Female; Follow-Up Studies; Hepatitis B, Chronic; Humans; L-Lactate Dehydrogenase; Lactates; Male; Middle Aged; Muscle Weakness; Muscle, Skeletal; Muscular Diseases; Prospective Studies; Retrospective Studies; Young Adult	2010
Efficacy of initial treatment with clevudine in naive patients with chronic hepatitis B. The Korean journal of internal medicine, 2010, Volume: 25, Issue:4 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Retrospective Studies	2010
18F-FDG PET/CT of drug-induced myopathy in a patient with chronic hepatitis B on long-term clevudine therapy. European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:4 Topics: Adult; Arabinofuranosyluracil; Fluorodeoxyglucose F18; Hepatitis B, Chronic; Humans; Male; Muscular Diseases; Positron-Emission Tomography; Time Factors; Tomography, X-Ray Computed	2011
[New drugs of treatment of patients with chronic hepatitis B]. Nihon rinsho. Japanese journal of clinical medicine, 2011, Volume: 69 Suppl 4 Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine	2011
Experience of anti-viral therapy in hepatitis B-associated membranous nephropathy, including Lamivudine-resistant strains. The Korean journal of internal medicine, 2012, Volume: 27, Issue:4 Topics: Adenine; Adult; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Viral; Female; Glomerulonephritis, Membranous; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Young Adult	2012
Long-term treatment outcomes of clevudine in antiviral-naive patients with chronic hepatitis B. World journal of gastroenterology, 2012, Dec-21, Volume: 18, Issue:47 Topics: Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Retrospective Studies; Treatment Outcome	2012
[Efficacy of entecavir switching therapy in chronic hepatitis B patients with clevudine-induced myopathy]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2013, Jan-25, Volume: 61, Issue:1 Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Muscular Diseases	2013
Immunogenic effects of woodchuck hepatitis virus surface antigen vaccine in combination with antiviral therapy: breaking of humoral and cellular immune tolerance in chronic woodchuck hepatitis virus infection. Intervirology, 2002, Volume: 45, Issue:4-6 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Hepatitis B Antibodies; Hepatitis B Vaccines; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Immunity, Cellular; Marmota; Vaccination	2002
Effects of pyrimidine and purine analog combinations in the duck hepatitis B virus infection model. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:6 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Blotting, Southern; Cell Survival; Deoxycytidine; Dioxolanes; Disease Models, Animal; Drug Therapy, Combination; Ducks; Emtricitabine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis B, Chronic; Hepatitis, Viral, Animal; Hepatocytes; Polymerase Chain Reaction; Purine Nucleosides; Reverse Transcriptase Inhibitors; Viral Load; Virus Replication	2003
Adenovirus-based gene therapy during clevudine treatment of woodchucks chronically infected with woodchuck hepatitis virus. Virology, 2004, Sep-15, Volume: 327, Issue:1 Topics: Adenoviridae; Animals; Antiviral Agents; Arabinofuranosyluracil; Baculoviridae; beta-Galactosidase; Cell Line; Combined Modality Therapy; Genetic Therapy; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Interferon-gamma; Marmota; Treatment Outcome; Tumor Necrosis Factor-alpha	2004
Clevudine therapy with vaccine inhibits progression of chronic hepatitis and delays onset of hepatocellular carcinoma in chronic woodchuck hepatitis virus infection. Antiviral therapy, 2004, Volume: 9, Issue:6 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Disease Progression; Female; Hepatitis B Vaccines; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Humans; Liver Neoplasms; Male; Marmota; Viral Load	2004
Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:10 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Hepatitis Antigens; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Hepatitis Delta Virus; Kinetics; Marmota; Pilot Projects; Time Factors; United States; Viremia	2005
Chemoimmunotherapy of chronic hepatitis B virus infection in the woodchuck model overcomes immunologic tolerance and restores T-cell responses to pre-S and S regions of the viral envelope protein. Journal of virology, 2007, Volume: 81, Issue:19 Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Carrier State; Combined Modality Therapy; Disease Models, Animal; Epitopes; Female; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Immune Tolerance; Immunotherapy; Marmota; T-Lymphocytes; Vaccination; Viral Envelope Proteins	2007
A novel mutation pattern emerging during lamivudine treatment shows cross-resistance to adefovir dipivoxil treatment. Antiviral therapy, 2007, Volume: 12, Issue:5 Topics: Adenine; Adult; Arabinofuranosyluracil; Base Sequence; Cell Line, Tumor; Cloning, Molecular; Deoxycytidine; DNA Mutational Analysis; DNA, Viral; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Viral; Emtricitabine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Molecular Sequence Data; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Tenofovir; Time Factors; Transfection; Treatment Outcome; Viral Load; Virus Replication	2007
Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax). Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:1 Topics: Animals; Antigens, Surface; Antiviral Agents; Arabinofuranosyluracil; DNA Replication; DNA, Circular; DNA, Viral; Dose-Response Relationship, Drug; Gene Expression; Genes, Viral; Hepatitis Antigens; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Hepatitis C Antigens; Marmota; RNA, Viral; Time Factors; Viremia; Virus Replication	2001
Immunization with surface antigen vaccine alone and after treatment with 1-(2-fluoro-5-methyl-beta-L-arabinofuranosyl)-uracil (L-FMAU) breaks humoral and cell-mediated immune tolerance in chronic woodchuck hepatitis virus infection. Journal of virology, 2002, Volume: 76, Issue:11 Topics: Animals; Antibody Formation; Antigens, Surface; Antigens, Viral; Antiviral Agents; Arabinofuranosyluracil; Carrier State; Hepatitis B Vaccines; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Immune Tolerance; Immunity, Cellular; Marmota; Vaccination	2002