Page last updated: 2024-09-04

2'-fluorothymidine and Benign Neoplasms

2'-fluorothymidine has been researched along with Benign Neoplasms in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's1 (8.33)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alauddin, MM1
Collins, JM; Douglas, KA; Jones, SK; Lawhorn-Crews, JM; Mangner, TJ; McHugh, CI; Modi, D; Shields, AF1
Emerick, LE; Krohn, KA; Plotnik, DA; Schwartz, JL; Unadkat, JD1
Grierson, JR; Jordan, R; Krohn, KA; Schwartz, JL; Tamura, Y1
Collins, JM; Douglas, K; Mangner, TJ; Muzik, O; Shields, AF; Sloan, A; Sun, H; Vaishampayan, U1
Douglas, KA; Lawhorn-Crews, JM; Shields, AF; Tehrani, OS1
Collins, JM; Katki, AG; Klecker, RW1
Cheng, YC1
Hill, DL; Nan, L; Oliver, P; Rhie, JK; Wang, H; Wang, S; Wang, Z; Zhang, R1
Abbruzzese, JL; Castellanos, AM; Krakoff, IH; Legha, SS; Levy, JK; Raber, MN; Schmidt, S1
Burchenal, JH; Fanucchi, MP; Fox, JJ; Leyland-Jones, B; Watanabe, KA; Young, CW1
Krohn, KA; Mankoff, DA; Shields, AF1

Reviews

2 review(s) available for 2'-fluorothymidine and Benign Neoplasms

ArticleYear
Journey of 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU): from Antiviral Drug to PET Imaging Agent.
    Current medicinal chemistry, 2018, Volume: 25, Issue:16

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Carbon Radioisotopes; Contrast Media; Fluorine Radioisotopes; Humans; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals

2018
PET imaging of cellular proliferation.
    Radiologic clinics of North America, 2005, Volume: 43, Issue:1

    Topics: Cell Division; Humans; Neoplasms; Positron-Emission Tomography; Thymidine

2005

Trials

1 trial(s) available for 2'-fluorothymidine and Benign Neoplasms

ArticleYear
Imaging DNA synthesis with [18F]FMAU and positron emission tomography in patients with cancer.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:1

    Topics: Adult; Aged; Arabinofuranosyluracil; Biomarkers, Tumor; DNA, Neoplasm; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Organ Specificity; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution

2005

Other Studies

9 other study(ies) available for 2'-fluorothymidine and Benign Neoplasms

ArticleYear
Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents:
    Cancer imaging : the official publication of the International Cancer Imaging Society, 2016, Oct-17, Volume: 16, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Capecitabine; Dideoxynucleosides; Female; Humans; Male; Middle Aged; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals

2016
Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:9

    Topics: Arabinofuranosyluracil; Biological Transport; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Equilibrative Nucleoside Transport Proteins; Humans; Kinetics; Neoplasms; Positron-Emission Tomography; Thymidine; Tritium

2010
Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:12

    Topics: Animals; Arabinofuranosyluracil; Cell Division; Cell Line, Tumor; Dideoxynucleosides; DNA; Drug Delivery Systems; Humans; Metabolic Clearance Rate; Mice; Neoplasm Staging; Neoplasms; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Tomography, Emission-Computed; Tritium

2003
Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:8

    Topics: Arabinofuranosyluracil; Cell Line, Tumor; Humans; Mitochondria; Neoplasms; Oxidative Stress; Radionuclide Imaging; Radiopharmaceuticals; Thymidine Kinase; Tritium

2008
Suicide prodrugs activated by thymidylate synthase: rationale for treatment and noninvasive imaging of tumors with deoxyuridine analogues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:8

    Topics: Animals; Arabinofuranosyluracil; Cell Division; DNA; Floxuridine; Fluorine Radioisotopes; Humans; Methylation; Mice; Neoplasms; Phosphorylation; Prodrugs; Thymidylate Synthase; Tumor Cells, Cultured

1999
Potential use of antiviral L(-)nucleoside analogues for the prevention or treatment of viral associated cancers.
    Cancer letters, 2001, Volume: 162 Suppl

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Dioxolanes; Hepatitis B virus; Herpesvirus 4, Human; Humans; Neoplasms; Nucleosides; Stereoisomerism; Structure-Activity Relationship; Uracil; Virus Diseases; Zalcitabine

2001
Radiolabeled 2'-fluorodeoxyuracil-beta-D-arabinofuranoside (FAU) and 2'-fluoro-5-methyldeoxyuracil-beta -D-arabinofuranoside (FMAU) as tumor-imaging agents in mice.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:5

    Topics: Animals; Arabinofuranosyluracil; DNA, Neoplasm; Humans; Mice; Mice, SCID; Muscle, Skeletal; Neoplasm Transplantation; Neoplasms; Radiopharmaceuticals; Spleen; Thymidine; Tissue Distribution; Tomography, Emission-Computed; Transplantation, Heterologous

2002
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity.
    Investigational new drugs, 1989, Volume: 7, Issue:2-3

    Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Colonic Neoplasms; Drug Evaluation; Electroencephalography; Female; Fibrosarcoma; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nervous System Diseases; Nervous System Neoplasms

1989
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU).
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Central Nervous System Diseases; Drug Evaluation; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Platelet Count; Uridine; Vomiting

1985