Page last updated: 2024-08-21

2'-deoxyadenosine triphosphate and Severe Combined Immunodeficiency

2'-deoxyadenosine triphosphate has been researched along with Severe Combined Immunodeficiency in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blackburn, MR; Joachims, ML; Laurent, AB; Marble, PA; Paliotta, M; Pastuszko, P; Thompson, LF1
Hirschhorn, R; Huie, ML; Israni, A; Ownby, DR; Yang, DR1
Aldrich, M; Blackburn, MR; Chen, W; Datta, SK; Hershfield, MS; Kellems, RE; Kelly, S; Volmer, JB; Zhong, H1
Apasov, SG; Blackburn, MR; Kellems, RE; Sitkovsky, MV; Smith, PT1
Bain, MD; Bax, BE; Chalmers, RA; Fairbanks, LD; Simmonds, HA; Webster, AD1
Duley, JA; Fairbanks, LD; Flood, T; Gaspar, HB; Simmonds, HA; Steward, CA1
Borkowsky, W; Eng, F; Hirschhorn, R; Nicknam, MN; Yang, DR1

Other Studies

7 other study(ies) available for 2'-deoxyadenosine triphosphate and Severe Combined Immunodeficiency

ArticleYear
Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases.
    Journal of immunology (Baltimore, Md. : 1950), 2008, Dec-01, Volume: 181, Issue:11

    Topics: Adenosine Deaminase; Animals; Apoptosis; Cell Culture Techniques; Cell Differentiation; Coculture Techniques; Deoxyadenine Nucleotides; Disease Models, Animal; Enzyme Inhibitors; Fetus; Humans; Mice; Phosphotransferases (Alcohol Group Acceptor); Severe Combined Immunodeficiency; Thymus Gland

2008
Somatic mosaicism for a newly identified splice-site mutation in a patient with adenosine deaminase-deficient immunodeficiency and spontaneous clinical recovery.
    American journal of human genetics, 1994, Volume: 55, Issue:1

    Topics: Adenosine Deaminase; Alleles; Arginine; B-Lymphocytes; Base Sequence; Cell Line; Child, Preschool; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 20; Deoxyadenine Nucleotides; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Glutamine; Humans; Male; Molecular Sequence Data; Mosaicism; Point Mutation; Remission, Spontaneous; Repetitive Sequences, Nucleic Acid; RNA Splicing; RNA, Messenger; Severe Combined Immunodeficiency; Y Chromosome

1994
The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice. Differential impact on pulmonary and immunologic abnormalities.
    The Journal of biological chemistry, 2000, Oct-13, Volume: 275, Issue:41

    Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Deoxyadenine Nucleotides; Deoxyadenosines; Disease Models, Animal; Genotype; Histocytochemistry; Hydrolases; Killer Cells, Natural; Lung; Lymphocyte Count; Lymphocytes; Lymphopenia; Mice; Mice, Transgenic; Phenotype; S-Adenosylhomocysteine; Severe Combined Immunodeficiency; Spleen; Thymus Gland

2000
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.
    The Journal of clinical investigation, 2001, Volume: 108, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; B-Lymphocytes; Calcium Signaling; Cell Differentiation; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyadenosines; Gene Expression Regulation; Lectins, C-Type; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Knockout; Mice, SCID; Organ Specificity; Phosphorylation; Protein Processing, Post-Translational; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Interleukin-2; Severe Combined Immunodeficiency; Signal Transduction; Specific Pathogen-Free Organisms; Spleen; T-Lymphocytes; Thymus Gland

2001
Carrier erythrocyte entrapped adenosine deaminase therapy in adenosine deaminase deficiency.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adult; Deoxyadenine Nucleotides; Erythrocytes; Female; Humans; Hydrolases; Severe Combined Immunodeficiency; Treatment Outcome

2000
ADA activity and DATP levels in erythrocytes after bone marrow transplantation.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Adenosine Deaminase; Bone Marrow Transplantation; Deoxyadenine Nucleotides; Erythrocytes; Humans; Severe Combined Immunodeficiency; Treatment Outcome

2000
Novel deletion and a new missense mutation (Glu 217 Lys) at the catalytic site in two adenosine deaminase alleles of a patient with neonatal onset adenosine deaminase- severe combined immunodeficiency.
    Journal of immunology (Baltimore, Md. : 1950), 1992, Nov-01, Volume: 149, Issue:9

    Topics: Adenosine Deaminase; Alleles; Ampicillin; Base Sequence; Chromosomes, Human, Pair 2; Concanavalin A; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Probes; Drug Therapy, Combination; Gene Library; Gentamicins; Humans; Infant; Ketoconazole; Lymphocyte Activation; Male; Molecular Sequence Data; Oxacillin; Phytohemagglutinins; Point Mutation; Pokeweed Mitogens; Promoter Regions, Genetic; Restriction Mapping; Sequence Homology, Nucleic Acid; Severe Combined Immunodeficiency; Trimethoprim, Sulfamethoxazole Drug Combination

1992