Page last updated: 2024-08-21

2'-deoxyadenosine triphosphate and Leukemia, Lymphocytic

2'-deoxyadenosine triphosphate has been researched along with Leukemia, Lymphocytic in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarado, Y; Brown, RA; Cahill, A; Cortes, JE; DiPersio, JF; Faderl, S; Fracasso, PM; Gandhi, V; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; Lambert, P; Plunkett, W; Samson, T; Sznol, M; Thomas, DA; Verstovsek, S; Wright, LP1
Benjamin, RS; Freireich, EJ; Keating, MJ; Plunkett, W1
Bagnara, AS; Carson, DA; Fetter, JE; Hershfield, MS; Martin, DW; Small, WC; Ullman, B; Wasson, DB; Williams, SR1
Ackland, SP; Bagnara, AS; Hallam, LJ; Van der Weyden, MB; Whiteside, MG1
Fox, RM; Taylor, IW; Tripp, EH1
Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF1
Fox, RM; Kefford, RF1
Ganeshaguru, K; Hoffbrand, AV; Murphy, P; Piga, A; Prentice, HG; Russell, NH; Sylwestrowicz, T1
Begleiter, A; Israels, LG; Johnston, JB; Pugh, L1
Fox, RM; Mann, GJ1
Begleiter, A; Glazer, RI; Israels, LG; Johnston, JB; Pugh, L1
Catovsky, D; Ganeshaguru, K; Ho, AD; Hoffbrand, AV; Piga, A1

Trials

1 trial(s) available for 2'-deoxyadenosine triphosphate and Leukemia, Lymphocytic

ArticleYear
Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia.
    Leukemia research, 2003, Volume: 27, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA, Neoplasm; Enzyme Inhibitors; Female; Humans; Infusions, Intravenous; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Male; Middle Aged; Pyridines; Ribonucleotide Reductases; Safety; Thiosemicarbazones

2003

Other Studies

11 other study(ies) available for 2'-deoxyadenosine triphosphate and Leukemia, Lymphocytic

ArticleYear
Modulation of 9-beta-D-arabinofuranosyladenine 5'-triphosphate and deoxyadenosine triphosphate in leukemic cells by 2'-deoxycoformycin during therapy with 9-beta-D-arabinofuranosyladenine.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Adult; Arabinonucleotides; Cell Line; Chromatography, High Pressure Liquid; Coformycin; Deoxyadenine Nucleotides; DNA; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Male; Pentostatin; Ribonucleosides; Vidarabine; Vidarabine Phosphate

1982
Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells.
    The Journal of biological chemistry, 1982, Jun-10, Volume: 257, Issue:11

    Topics: Adenosine Kinase; Cell Line; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Humans; Kinetics; Leukemia, Lymphoid; Mutation; Phosphotransferases; T-Lymphocytes

1982
The biochemical and clinical consequences of 2'-deoxycoformycin in T cell chronic lymphocytic leukaemia.
    Scandinavian journal of haematology, 1984, Volume: 32, Issue:1

    Topics: Adenosine Deaminase; Adenosine Triphosphate; Adenosylhomocysteinase; AMP Deaminase; Coformycin; Cytotoxicity, Immunologic; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Hydrolases; Leukemia, Lymphoid; Male; Middle Aged; Pentostatin; Ribonucleosides; T-Lymphocytes

1984
Deoxyadenosine induced G1 phase arrest in leukemic T cells.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxyadenosines; DNA, Neoplasm; Flow Cytometry; Humans; Interphase; Kinetics; Leukemia, Lymphoid; T-Lymphocytes

1984
Studies on the biochemical sequelae of therapy in Thy-acute lymphoblastic leukaemia with the adenosine deaminase inhibitor 2' deoxycoformycin.
    British journal of haematology, 1981, Volume: 49, Issue:1

    Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydrolases; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Ribonucleosides; Thymine Nucleotides

1981
Deoxycoformycin-induced response in chronic lymphocytic leukaemia: deoxyadenosine toxicity in non-replicating lymphocytes.
    British journal of haematology, 1982, Volume: 50, Issue:4

    Topics: Adenosine Deaminase Inhibitors; Cell Survival; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Replication; Humans; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Pentostatin; Ribonucleosides

1982
The effect of deoxycoformycin and deoxyadenosine on deoxyribonucleotide concentrations in leukaemic cells.
    British journal of haematology, 1982, Volume: 51, Issue:4

    Topics: Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxyribonucleotides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Pentostatin; Ribonucleosides; T-Lymphocytes

1982
Enhanced cytotoxicity and inhibition of DNA damage repair in irradiated murine L5178Y lymphoblasts and human chronic lymphocytic leukemia cells treated with 2'-deoxycoformycin and deoxyadenosine in vitro.
    Cancer research, 1988, Jul-15, Volume: 48, Issue:14

    Topics: Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; DNA Repair; Drug Synergism; Leukemia L5178; Leukemia, Experimental; Leukemia, Lymphoid; Mice; NAD; Pentostatin; Ribonucleosides

1988
Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:5

    Topics: B-Lymphocytes; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyguanosine; DNA; Humans; Leukemia, Lymphoid; T-Lymphocytes

1986
Induction of DNA strand breaks in chronic lymphocytic leukemia following treatment with 2'-deoxycoformycin in vivo and in vitro.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenosine Deaminase Inhibitors; Aged; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Humans; Leukemia, Lymphoid; Male; Middle Aged; Monocytes; NAD; Pentostatin; Ribonucleosides

1987
Biochemical mechanisms of deoxycoformycin toxicity in chronic leukemias.
    Leukemia research, 1987, Volume: 11, Issue:10

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Coformycin; Deoxyadenine Nucleotides; Deoxyadenosines; DNA Damage; Humans; Leukemia, Lymphoid; NAD; Pentostatin; Ribonucleosides

1987