2--6--dihydroxy-4--methoxychalcone and Leishmaniasis

2--6--dihydroxy-4--methoxychalcone has been researched along with Leishmaniasis* in 1 studies

Other Studies

1 other study(ies) available for 2--6--dihydroxy-4--methoxychalcone and Leishmaniasis

ArticleYear
Improvement of in vitro and in vivo antileishmanial activities of 2', 6'-dihydroxy-4'-methoxychalcone by entrapment in poly(D,L-lactide) nanoparticles.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:7

    The inhibition of intracellular Leishmania amazonensis growth by 2', 6'-dihydroxy-4'-methoxychalcone (DMC) isolated from Piper aduncum was further enhanced after encapsulation of DMC in polymeric nanoparticles. Encapsulated DMC also showed increased antileishmanial activity in infected BALB/c mice, as evidenced by significantly smaller lesions and fewer parasites in the lesions.

    Topics: Animals; Antiparasitic Agents; Chalcone; Chalcones; Drug Delivery Systems; Female; Leishmania; Leishmaniasis; Mice; Mice, Inbred BALB C; Polyesters

1999