Page last updated: 2024-09-02

2'-5'-oligoadenylate trimer and Viral Diseases

2'-5'-oligoadenylate trimer has been researched along with Viral Diseases in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Brinkmann, MM; Halle, S; Rex, V; Stempel, M1
Ghosh, A; Harioudh, MK; Perez, J; Sarkar, SN; Shao, L1
Buschard, K; Dahl-Jørgensen, K; Gerling, IC; Haupt-Jorgensen, M; Kaur, S; Krogvold, L; Pedersen, K; Pociot, F1
Hoshino, SI; Hosoda, N; Imataka, H; Kawashima, S; Kitade, Y; Kitamura, Y; Nagai, T; Nishiura, K; Nogimori, T; Oishi, Y1
Bisbal, C; Salehzada, T1
Ablashi, DV; Carter, WA; Henry, B; Hitzges, P; Müller, WE; Peterson, DL; Reichenbach, NL; Schröder, HC; Sobol, RW; Suhadolnik, RJ1
Castelli, J; Wood, KA; Youle, RJ1
Barber, GN1
Barak, Z; Edelbaum, O; Grafi, G; Raber, J; Sela, I; Sher, N; Stram, Y1
Oediger, H; Paessens, A; Streissle, G1
Alderson, T1
Cailla, H; Luxembourg, A; Roudier, J; Roux, H1

Reviews

6 review(s) available for 2'-5'-oligoadenylate trimer and Viral Diseases

ArticleYear
The two faces of oligoadenylate synthetase-like: effective antiviral protein and negative regulator of innate immunity.
    Current opinion in virology, 2023, Volume: 60

    Topics: 2',5'-Oligoadenylate Synthetase; Antiviral Agents; Humans; Immunity, Innate; Interferon Type I; Ligases; Virus Diseases; Viruses

2023
The Many Faces of Oligoadenylate Synthetases.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2023, Volume: 43, Issue:11

    Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Endoribonucleases; Humans; Interferons; Oligoribonucleotides; RNA, Double-Stranded; Virus Diseases

2023
The 2-5A system in viral infection and apoptosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1998, Volume: 52, Issue:9

    Topics: Adenine Nucleotides; Animals; Antiviral Agents; Apoptosis; Endoribonucleases; Humans; Oligoribonucleotides; RNA; Virus Diseases

1998
Host defense, viruses and apoptosis.
    Cell death and differentiation, 2001, Volume: 8, Issue:2

    Topics: Adenine Nucleotides; Animals; Antigens, CD; Apoptosis; Apoptosis Regulatory Proteins; eIF-2 Kinase; Endoribonucleases; fas Receptor; Genes, Regulator; Humans; Interferons; Membrane Glycoproteins; Mitochondria; Neoplasm Proteins; Neoplasms; Nuclear Proteins; Oligoribonucleotides; Promyelocytic Leukemia Protein; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; RNA, Double-Stranded; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Virus Diseases; Viruses

2001
New antiviral compounds.
    Advances in virus research, 1985, Volume: 30

    Topics: Adenine Nucleotides; Animals; Antibodies, Viral; Antiviral Agents; Axonal Transport; Carrier Proteins; Humans; Interferon Inducers; Liposomes; Oligoribonucleotides; Virus Diseases; Virus Physiological Phenomena; Virus Replication; Viruses

1985
Ribonucleotide metabolism--fresh approaches to viral and cancer chemotherapy.
    Biological reviews of the Cambridge Philosophical Society, 1989, Volume: 64, Issue:2

    Topics: Adenine Nucleotides; Animals; Antineoplastic Agents; Antiviral Agents; Dinucleoside Phosphates; Humans; Neoplasms; Oligoribonucleotides; Ribonucleotides; Virus Diseases

1989

Trials

1 trial(s) available for 2'-5'-oligoadenylate trimer and Viral Diseases

ArticleYear
Upregulation of the 2-5A synthetase/RNase L antiviral pathway associated with chronic fatigue syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18 Suppl 1

    Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Antiviral Agents; Endoribonucleases; Fatigue Syndrome, Chronic; Female; Humans; Male; Middle Aged; Oligoribonucleotides; Poly I-C; Poly U; RNA, Double-Stranded; Up-Regulation; Virus Diseases

1994

Other Studies

5 other study(ies) available for 2'-5'-oligoadenylate trimer and Viral Diseases

ArticleYear
Genetic predisposition in the 2'-5'A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity.
    Diabetologia, 2021, Volume: 64, Issue:8

    Topics: Adenine Nucleotides; Adult; Antiviral Agents; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Immunity, Innate; Male; Oligoribonucleotides; Polymorphism, Single Nucleotide; RNA-Binding Proteins; RNA, Messenger; Virus Diseases; Young Adult

2021
Dom34 mediates targeting of exogenous RNA in the antiviral OAS/RNase L pathway.
    Nucleic acids research, 2019, 01-10, Volume: 47, Issue:1

    Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Endonucleases; Endoribonucleases; Gene Expression Regulation, Viral; Humans; Nuclear Proteins; Oligoribonucleotides; Ribosomes; RNA Stability; RNA, Double-Stranded; RNA, Viral; Signal Transduction; Virus Diseases; Virus Replication; Viruses

2019
[RNase L, a crucial mediator of innate immunity and other cell functions].
    Medecine sciences : M/S, 2008, Volume: 24, Issue:10

    Topics: 2',5'-Oligoadenylate Synthetase; Adenine Nucleotides; Adenocarcinoma; Animals; Apoptosis; Dimerization; Endoribonucleases; Enzyme Activation; Humans; Immunity, Innate; Interferon-alpha; Interferon-beta; Male; Mammals; Mice; Mice, Knockout; Oligoribonucleotides; Prostatic Neoplasms; RNA, Double-Stranded; RNA, Viral; Virus Diseases

2008
Induction of an ATP-polymerizing enzyme in TMV-infected tobacco and its homology to the human 2'-5' A synthetase.
    Virus genes, 1990, Volume: 4, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Base Sequence; Chromatography, Thin Layer; Cross Reactions; DNA, Viral; Enzyme Induction; Humans; Ligases; Oligoribonucleotides; Plants; Protein Synthesis Inhibitors; RNA, Messenger; Sequence Homology, Nucleic Acid; Tobacco Mosaic Virus; Virus Diseases

1990
Do viruses play an etiologic role in ankylosing spondylitis or psoriatic arthritis?
    Clinical immunology and immunopathology, 1987, Volume: 45, Issue:2

    Topics: Adenine Nucleotides; Adolescent; Adult; Aged; Aged, 80 and over; Arthritis; Arthritis, Rheumatoid; Chondrocalcinosis; Female; Humans; Male; Middle Aged; Oligoribonucleotides; Psoriasis; RNA Viruses; Spondylitis, Ankylosing; Virus Diseases; Virus Replication

1987