2---galloylhyperin and Chemical-and-Drug-Induced-Liver-Injury

2---galloylhyperin has been researched along with Chemical-and-Drug-Induced-Liver-Injury* in 1 studies

Other Studies

1 other study(ies) available for 2---galloylhyperin and Chemical-and-Drug-Induced-Liver-Injury

Article	Year
Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 102 2'-O-galloylhyperin (2'-O-GH), an active compound isolated from Pyrola calliantha, possesses remarkable antioxidant activity. The aims of this study were to investigate the hepatoprotective effect of 2'-O-GH against oxidative stress and elucidate the underlying mechanistic signaling pathways in HepG2 cells as well as in an animal model. Results showed that 2'-O-GH significantly inhibited hydrogen peroxide (H Topics: Animals; Antioxidant Response Elements; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gallic Acid; Hep G2 Cells; Humans; Hydrogen Peroxide; Liver; Male; Metabolic Networks and Pathways; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quercetin	2017

Article

Year

Hepatoprotective effect of 2'-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 102

2'-O-galloylhyperin (2'-O-GH), an active compound isolated from Pyrola calliantha, possesses remarkable antioxidant activity. The aims of this study were to investigate the hepatoprotective effect of 2'-O-GH against oxidative stress and elucidate the underlying mechanistic signaling pathways in HepG2 cells as well as in an animal model. Results showed that 2'-O-GH significantly inhibited hydrogen peroxide (H

Topics: Animals; Antioxidant Response Elements; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Gallic Acid; Hep G2 Cells; Humans; Hydrogen Peroxide; Liver; Male; Metabolic Networks and Pathways; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Protective Agents; Quercetin

2017