Compounds > 2-(n-(7-nitrobenz-2-oxa-1-3-diazol-4-yl)amino)-2-deoxyglucose

2-(n-(7-nitrobenz-2-oxa-1-3-diazol-4-yl)amino)-2-deoxyglucose and Triple-Negative-Breast-Neoplasms

2-(n-(7-nitrobenz-2-oxa-1-3-diazol-4-yl)amino)-2-deoxyglucose has been researched along with Triple-Negative-Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 2-(n-(7-nitrobenz-2-oxa-1-3-diazol-4-yl)amino)-2-deoxyglucose and Triple-Negative-Breast-Neoplasms

Article	Year
A GLUT1 inhibitor-based probe significantly ameliorates the sensitivity of tumor detection and diagnostic imaging. Chemical communications (Cambridge, England), 2021, Jun-03, Volume: 57, Issue:45 We report a non-antibody GLUT1 inhibitor probe NBDQ that is 30 times more sensitive than the traditional GLUT1 transportable tracer for cancer cell imaging and Warburg effect-based tumor detection. NBDQ reveals significant advantages in terms of tumor selectivity, fluorescence stability and in vivo biocompatibility in xenograft tumor imaging, including triple-negative breast cancer. Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Biocompatible Materials; Biomarkers, Tumor; Cell Line, Tumor; Cell Membrane Permeability; Deoxyglucose; Fluorescent Dyes; Glucose Transporter Type 1; Humans; Mice; Multimodal Imaging; Neoplasms, Experimental; Optical Imaging; Positron-Emission Tomography; Triple Negative Breast Neoplasms	2021

Article

Year

A GLUT1 inhibitor-based probe significantly ameliorates the sensitivity of tumor detection and diagnostic imaging.

Chemical communications (Cambridge, England), 2021, Jun-03, Volume: 57, Issue:45

We report a non-antibody GLUT1 inhibitor probe NBDQ that is 30 times more sensitive than the traditional GLUT1 transportable tracer for cancer cell imaging and Warburg effect-based tumor detection. NBDQ reveals significant advantages in terms of tumor selectivity, fluorescence stability and in vivo biocompatibility in xenograft tumor imaging, including triple-negative breast cancer.

Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Biocompatible Materials; Biomarkers, Tumor; Cell Line, Tumor; Cell Membrane Permeability; Deoxyglucose; Fluorescent Dyes; Glucose Transporter Type 1; Humans; Mice; Multimodal Imaging; Neoplasms, Experimental; Optical Imaging; Positron-Emission Tomography; Triple Negative Breast Neoplasms

2021