2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Uterine Neoplasms in 3 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uterine leiomyosarcoma is a severe neoplasia resistant to conventional therapies." | 1.42 | LY294002 induces in vitro apoptosis and overexpression of p75NTR in human uterine leiomyosarcoma HTB 114 cells. ( Crispoltoni, L; Montagnoli, C; Pistilli, A; Rende, M; Stabile, AM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pistilli, A | 1 |
| Rende, M | 1 |
| Crispoltoni, L | 1 |
| Montagnoli, C | 1 |
| Stabile, AM | 1 |
| Friedman, N | 1 |
| Shushan, A | 1 |
| Rojansky, N | 1 |
| Shveiky, D | 1 |
| Levitzki, R | 1 |
| Chaouat, M | 1 |
| Ben-Bassat, H | 1 |
| Yin, XJ | 1 |
| Wang, G | 1 |
| Khan-Dawood, FS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role and Clinical Relevance of Nerve Growth Factor (NGF) and Its Receptors (TrKA and p75NTR) in Patients With Erectile Dysfunction and Diabetes With or Wothout Metabolic Syndrome[NCT03862547] | 40 participants (Anticipated) | Interventional | 2019-01-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Uterine Neoplasms
| Article | Year |
|---|---|
LY294002 induces in vitro apoptosis and overexpression of p75NTR in human uterine leiomyosarcoma HTB 114 cells.
Topics: Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Activation; Enz | 2015 |
Targeting leiomyomas with all-trans-retinoic acid at phosphoinositide 3-kinase pathway suppression: Effective roles of β-catenin and of signaling interactions.
Topics: Adult; bcl-Associated Death Protein; beta Catenin; Cell Line, Tumor; Chromones; Female; Humans; Hyst | 2016 |
Requirements of phosphatidylinositol-3 kinase and mammalian target of rapamycin for estrogen-induced proliferation in uterine leiomyoma- and myometrium-derived cell lines.
Topics: Cell Line, Tumor; Cell Proliferation; Chromones; Enzyme Inhibitors; Estradiol; Female; G1 Phase; Hum | 2007 |