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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Thrombocythemia, Essential

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Thrombocythemia, Essential in 1 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Thrombocythemia, Essential: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.

Research Excerpts

ExcerptRelevanceReference
"R115777 is an orally bioavailable farnesyltransferase inhibitor (FTI) that has displayed encouraging activity in patients with acute myeloid leukemia."1.32In vitro antiproliferative activity of the farnesyltransferase inhibitor R115777 in hematopoietic progenitors from patients with myelofibrosis with myeloid metaplasia. ( Gray, LA; Kaufmann, SH; Mesa, RA; Reeder, T; Schroeder, G; Tefferi, A, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mesa, RA1
Tefferi, A1
Gray, LA1
Reeder, T1
Schroeder, G1
Kaufmann, SH1

Other Studies

1 other study available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Thrombocythemia, Essential

ArticleYear
In vitro antiproliferative activity of the farnesyltransferase inhibitor R115777 in hematopoietic progenitors from patients with myelofibrosis with myeloid metaplasia.
    Leukemia, 2003, Volume: 17, Issue:5

    Topics: Adult; Aged; Alkyl and Aryl Transferases; Antineoplastic Agents; Calcium-Calmodulin-Dependent Protei

2003