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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Scleroderma, Systemic

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Scleroderma, Systemic in 2 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamane, K2
Ihn, H2
Kubo, M1
Tamaki, K2

Other Studies

2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Scleroderma, Systemic

ArticleYear
Increased transcriptional activities of transforming growth factor beta receptors in scleroderma fibroblasts.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:9

    Topics: Activin Receptors, Type I; Cells, Cultured; Chromones; Collagen Type I; Enzyme Inhibitors; Fibroblas

2002
Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblast
    Arthritis and rheumatism, 2003, Volume: 48, Issue:6

    Topics: Androstadienes; Cells, Cultured; Chromones; Dactinomycin; Dermis; Dose-Response Relationship, Drug;

2003