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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Pulmonary Fibrosis

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Pulmonary Fibrosis in 3 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary fibrosis is the primary reason for mortality in patients with paraquat (PQ) poisoning."8.02Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis. ( Jin, W; Liu, K; Lu, J; Meng, X; Wang, R; Xie, H; Zhu, Y, 2021)
"Pulmonary fibrosis is the primary reason for mortality in patients with paraquat (PQ) poisoning."4.02Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis. ( Jin, W; Liu, K; Lu, J; Meng, X; Wang, R; Xie, H; Zhu, Y, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Hu, X1
Xu, Q1
Wan, H1
Hu, Y1
Xing, S1
Yang, H1
Gao, Y1
He, Z1
Meng, X1
Liu, K1
Xie, H1
Zhu, Y1
Jin, W1
Lu, J1
Wang, R1
Renigunta, A1
Hild, C1
Rose, F1
Klepetko, W1
Grimminger, F1
Seeger, W1
Hänze, J1

Other Studies

3 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Pulmonary Fibrosis

ArticleYear
PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:6

    Topics: Animals; Cell Line; Chromones; Collagen; Fibroblasts; Glycolysis; Lipopolysaccharides; Lung; Male; M

2020
Endoplasmic reticulum stress promotes epithelial‑mesenchymal transition via the PERK signaling pathway in paraquat‑induced pulmonary fibrosis.
    Molecular medicine reports, 2021, Volume: 24, Issue:1

    Topics: Alveolar Epithelial Cells; Animals; Cell Line; Chromones; eIF-2 Kinase; Endoplasmic Reticulum Stress

2021
Human RELMbeta is a mitogenic factor in lung cells and induced in hypoxia.
    FEBS letters, 2006, Feb-06, Volume: 580, Issue:3

    Topics: Androstadienes; Animals; Cell Hypoxia; Cell Line; Cell Proliferation; Chromones; Connective Tissue;

2006