2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Primary Ovarian Insufficiency in 1 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Y | 1 |
| Yao, R | 1 |
| Yang, Z | 1 |
| Li, S | 1 |
| Meng, W | 1 |
| Zhang, Y | 2 |
| Luo, H | 1 |
1 other study available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Topics: Adult; Apoptosis; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cellular Microenvironme | 2022 |