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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Precursor Cell Lymphoblastic Leukemia-Lymphoma

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 5 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weston, VJ1
Wei, W1
Stankovic, T1
Kearns, P1
Spijkers-Hagelstein, JA1
Pinhanços, SS1
Schneider, P1
Pieters, R1
Stam, RW1
Juarez, JG1
Thien, M1
Dela Pena, A1
Baraz, R1
Bradstock, KF1
Bendall, LJ1
Uddin, S1
Hussain, A1
Al-Hussein, K1
Platanias, LC1
Bhatia, KG1
Gu, L1
Findley, HW1
Zhu, N1
Zhou, M1

Other Studies

5 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Precursor Cell Lymphoblastic Leukemia-Lymphoma

ArticleYear
Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1.
    Experimental hematology, 2018, Volume: 63

    Topics: Butadienes; Cell Cycle; Chromones; Daunorubicin; Down-Regulation; Drug Synergism; Gene Expression Pr

2018
Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL.
    Leukemia, 2014, Volume: 28, Issue:4

    Topics: Cell Line, Tumor; Chromones; Drug Resistance; Gene Rearrangement; Genomics; Glucocorticoids; Histone

2014
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Animals; B-Lymphocytes; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis, L

2009
Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.
    Biochemical and biophysical research communications, 2004, Jul-30, Volume: 320, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Humans; Leukemia, T-Cell; Morpholines; Ph

2004
Endogenous TNFalpha mediates cell survival and chemotherapy resistance by activating the PI3K/Akt pathway in acute lymphoblastic leukemia cells.
    Leukemia, 2006, Volume: 20, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Chromones; Drug Res

2006