2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 5 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weston, VJ | 1 |
| Wei, W | 1 |
| Stankovic, T | 1 |
| Kearns, P | 1 |
| Spijkers-Hagelstein, JA | 1 |
| Pinhanços, SS | 1 |
| Schneider, P | 1 |
| Pieters, R | 1 |
| Stam, RW | 1 |
| Juarez, JG | 1 |
| Thien, M | 1 |
| Dela Pena, A | 1 |
| Baraz, R | 1 |
| Bradstock, KF | 1 |
| Bendall, LJ | 1 |
| Uddin, S | 1 |
| Hussain, A | 1 |
| Al-Hussein, K | 1 |
| Platanias, LC | 1 |
| Bhatia, KG | 1 |
| Gu, L | 1 |
| Findley, HW | 1 |
| Zhu, N | 1 |
| Zhou, M | 1 |
5 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Synergistic action of dual IGF1/R and MEK inhibition sensitizes childhood acute lymphoblastic leukemia (ALL) cells to cytotoxic agents and involves downregulation of STAT6 and PDAP1.
Topics: Butadienes; Cell Cycle; Chromones; Daunorubicin; Down-Regulation; Drug Synergism; Gene Expression Pr | 2018 |
Chemical genomic screening identifies LY294002 as a modulator of glucocorticoid resistance in MLL-rearranged infant ALL.
Topics: Cell Line, Tumor; Chromones; Drug Resistance; Gene Rearrangement; Genomics; Glucocorticoids; Histone | 2014 |
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
Topics: Animals; B-Lymphocytes; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis, L | 2009 |
Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.
Topics: Apoptosis; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Humans; Leukemia, T-Cell; Morpholines; Ph | 2004 |
Endogenous TNFalpha mediates cell survival and chemotherapy resistance by activating the PI3K/Akt pathway in acute lymphoblastic leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Chromones; Drug Res | 2006 |