2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Pituitary Neoplasms in 4 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TSH-secreting pituitary tumors (TSHomas) are pituitary tumors that constitutively secrete TSH." | 1.35 | Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors. ( Cheng, SY; Furuya, F; Lu, C; Willingham, MC, 2008) |
| "As for any solid tumour, pituitary adenoma expansion is dependent on neovascularization through angiogenesis." | 1.33 | Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: detection of a non-endothelial function of VEGF in pituitary tumours. ( Arzt, E; Lange, M; Losa, M; Onofri, C; Renner, U; Stalla, GK; Theodoropoulou, M; Uhl, E, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, H | 1 |
| Zhu, D | 1 |
| Zhang, G | 1 |
| Luo, X | 1 |
| Xie, W | 1 |
| Jackson, TA | 1 |
| Koterwas, DM | 1 |
| Morgan, MA | 1 |
| Bradford, AP | 1 |
| Onofri, C | 1 |
| Theodoropoulou, M | 1 |
| Losa, M | 1 |
| Uhl, E | 1 |
| Lange, M | 1 |
| Arzt, E | 1 |
| Stalla, GK | 1 |
| Renner, U | 1 |
| Lu, C | 1 |
| Willingham, MC | 1 |
| Furuya, F | 1 |
| Cheng, SY | 1 |
4 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Pituitary Neoplasms
| Article | Year |
|---|---|
AFAP1-AS1 Promotes Proliferation of Pituitary Adenoma Cells through miR-103a-3p to Activate PI3K/AKT Signaling Pathway.
Topics: Adenoma; Animals; Cell Line, Tumor; Cell Proliferation; Chromones; Enzyme Inhibitors; MicroRNAs; Mor | 2019 |
Fibroblast growth factors regulate prolactin transcription via an atypical Rac-dependent signaling pathway.
Topics: Androstadienes; Animals; Bridged-Ring Compounds; Cell Line, Tumor; Chromones; Culture Media, Serum-F | 2003 |
Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: detection of a non-endothelial function of VEGF in pituitary tumours.
Topics: Adenoma; Adult; Aged; Animals; Antibodies, Monoclonal; Blotting, Western; Cell Line, Tumor; Cell Pro | 2006 |
Activation of phosphatidylinositol 3-kinase signaling promotes aberrant pituitary growth in a mouse model of thyroid-stimulating hormone-secreting pituitary tumors.
Topics: Animals; Blotting, Western; Cell Survival; Chromones; Enzyme Activation; Mice; Mice, Knockout; Model | 2008 |