2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Parkinsonian Disorders in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is thought that Parkinson's disease involves apoptosis, and NGF prevents apoptosis in an in vivo model system." | 1.31 | Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease. ( Chiba, H; Shimoke, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, W | 1 |
| Luo, B | 1 |
| Qiu, C | 1 |
| Jiang, X | 1 |
| Shen, B | 1 |
| Zhang, L | 1 |
| Liu, W | 1 |
| Zhang, W | 1 |
| Shimoke, K | 1 |
| Chiba, H | 1 |
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Parkinsonian Disorders
| Article | Year |
|---|---|
TRIM3 attenuates apoptosis in Parkinson's disease via activating PI3K/AKT signal pathway.
Topics: Aged; Animals; Apoptosis; Carrier Proteins; Case-Control Studies; Cell Line; Cell Survival; Chromone | 2020 |
Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Chloromethyl Ketones; Amino Acid Substituti | 2001 |