2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Nerve Degeneration in 8 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infantile neuronal ceroid lipofuscinosis (INCL) is a childhood neurodegenerative disease caused by the selective death of cortical and retinal neurons as the result of an inherited palmitoyl-protein thioesterase 1 (PPT1) deficiency." | 1.31 | Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis. ( Cho, S; Dawson, G; Dawson, PE, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, W | 1 |
| Gao, G | 1 |
| Zhao, H | 1 |
| Xia, Y | 1 |
| Guo, X | 1 |
| Li, N | 1 |
| Li, Y | 1 |
| Yang, Y | 1 |
| Chen, L | 1 |
| Wang, Q | 1 |
| Li, L | 1 |
| Zheng, W | 1 |
| Chong, CM | 1 |
| Wang, H | 1 |
| Zhou, X | 1 |
| Zhang, L | 1 |
| Wang, R | 1 |
| Meng, Q | 1 |
| Lazarovici, P | 1 |
| Fang, J | 1 |
| Zhou, F | 1 |
| Gomi, M | 1 |
| Fujimoto, M | 1 |
| Hayase, M | 1 |
| Marumo, T | 1 |
| Masutani, H | 1 |
| Yodoi, J | 1 |
| Hashimoto, N | 1 |
| Nozaki, K | 1 |
| Takagi, Y | 1 |
| Simão, F | 1 |
| Zamin, LL | 1 |
| Frozza, R | 1 |
| Nassif, M | 1 |
| Horn, AP | 1 |
| Salbego, CG | 1 |
| Tovar-Y-Romo, LB | 1 |
| Tapia, R | 1 |
| Copanaki, E | 1 |
| Chang, S | 1 |
| Vlachos, A | 1 |
| Tschäpe, JA | 1 |
| Müller, UC | 1 |
| Kögel, D | 1 |
| Deller, T | 1 |
| Baki, L | 1 |
| Neve, RL | 1 |
| Shao, Z | 1 |
| Shioi, J | 1 |
| Georgakopoulos, A | 1 |
| Robakis, NK | 1 |
| Cho, S | 1 |
| Dawson, PE | 1 |
| Dawson, G | 1 |
8 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Nerve Degeneration
| Article | Year |
|---|---|
Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity.
Topics: Amyloid beta-Protein Precursor; Animals; Axons; Blotting, Western; Cells, Cultured; Chromones; Dopam | 2015 |
Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult.
Topics: Animals; Artemisinins; Cell Death; Cell Survival; Chromones; Flavonoids; MAP Kinase Signaling System | 2016 |
Attenuation of neuronal degeneration in thioredoxin-1 overexpressing mice after mild focal ischemia.
Topics: Analysis of Variance; Animals; Caspase 3; Cell Death; Chromones; Dicarbethoxydihydrocollidine; Disea | 2009 |
Protective profile of oxcarbazepine against oxygen-glucose deprivation in organotypic hippocampal slice culture could involve PI3K cell signaling pathway.
Topics: Analysis of Variance; Animals; Anticonvulsants; Blotting, Western; Carbamazepine; Cell Death; Chromo | 2009 |
VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Choline O-A | 2010 |
sAPPalpha antagonizes dendritic degeneration and neuron death triggered by proteasomal stress.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Ap | 2010 |
Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling.
Topics: Alzheimer Disease; Animals; Apoptosis; Brain; Caspases; Cells, Cultured; Chromones; Down-Regulation; | 2008 |
Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Chromones; Daunorubicin; Enzyme Inhibitors; Etoposide; Human | 2001 |