2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Muscle Contraction in 16 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sepsis was induced by cecal ligation and puncture (CLP)." | 1.51 | Neuregulin-1β attenuates sepsis-induced diaphragm atrophy by activating the PI3K/Akt signaling pathway. ( Chu, T; Jiang, P; Li, ST; Liu, H; Wu, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 11 (68.75) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, J | 1 |
| Liu, H | 1 |
| Chu, T | 1 |
| Jiang, P | 1 |
| Li, ST | 1 |
| Dwyer, DS | 1 |
| Aamodt, EJ | 1 |
| Dekkers, BG | 2 |
| Schaafsma, D | 2 |
| Tran, T | 1 |
| Zaagsma, J | 2 |
| Meurs, H | 2 |
| Ghosh-Choudhury, N | 1 |
| Abboud, SL | 1 |
| Chandrasekar, B | 1 |
| Ghosh Choudhury, G | 1 |
| Nolte, LA | 1 |
| Han, DH | 1 |
| Hansen, PA | 1 |
| Hucker, KA | 1 |
| Holloszy, JO | 1 |
| Su, X | 1 |
| Smolock, EM | 1 |
| Marcel, KN | 1 |
| Moreland, RS | 1 |
| Tolloczko, B | 1 |
| Turkewitsch, P | 1 |
| Al-Chalabi, M | 1 |
| Martin, JG | 1 |
| Huang, J | 1 |
| Mahavadi, S | 1 |
| Sriwai, W | 1 |
| Hu, W | 1 |
| Murthy, KS | 1 |
| McNeill, KD | 1 |
| Stelmack, GL | 1 |
| Gosens, R | 1 |
| Baarsma, HA | 1 |
| Frohwerk, E | 1 |
| Penninks, JM | 1 |
| Sharma, P | 1 |
| Ens, KM | 1 |
| Nelemans, SA | 1 |
| Halayko, AJ | 1 |
| Farghaly, HS | 1 |
| Blagbrough, IS | 1 |
| Medina-Tato, DA | 1 |
| Watson, ML | 1 |
| Hong, SJ | 1 |
| Chang, CC | 1 |
| Ibitayo, AI | 1 |
| Tsunoda, Y | 1 |
| Nozu, F | 1 |
| Owyang, C | 1 |
| Bitar, KN | 1 |
| Wojtaszewski, JF | 1 |
| Lynge, J | 1 |
| Jakobsen, AB | 1 |
| Goodyear, LJ | 2 |
| Richter, EA | 1 |
| Dyck, DJ | 1 |
| Steinberg, G | 1 |
| Bonen, A | 1 |
| Komalavilas, P | 1 |
| Mehta, S | 1 |
| Wingard, CJ | 1 |
| Dransfield, DT | 1 |
| Bhalla, J | 1 |
| Woodrum, JE | 1 |
| Molinaro, JR | 1 |
| Brophy, CM | 1 |
| Sakamoto, K | 1 |
| Hirshman, MF | 1 |
| Aschenbach, WG | 1 |
16 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Muscle Contraction
| Article | Year |
|---|---|
Neuregulin-1β attenuates sepsis-induced diaphragm atrophy by activating the PI3K/Akt signaling pathway.
Topics: Animals; Chromones; Diaphragm; Disease Models, Animal; Humans; Male; Morpholines; Muscle Contraction | 2019 |
Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation.
Topics: Animals; Arrestins; beta-Arrestins; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium | 2013 |
Insulin-induced laminin expression promotes a hypercontractile airway smooth muscle phenotype.
Topics: Administration, Inhalation; Animals; Cattle; Chromones; DNA Replication; In Vitro Techniques; Insuli | 2009 |
BMP-2 regulates cardiomyocyte contractility in a phosphatidylinositol 3 kinase-dependent manner.
Topics: Adenoviridae; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Catalytic Domain; | 2003 |
A peroxovanadium compound stimulates muscle glucose transport as powerfully as insulin and contractions combined.
Topics: Androstadienes; Animals; Chromones; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Insulin; Insuli | 2003 |
Phosphatidylinositol 3-kinase modulates vascular smooth muscle contraction by calcium and myosin light chain phosphorylation-independent and -dependent pathways.
Topics: Animals; Caffeine; Calcium; Carotid Arteries; Chromones; Enzyme Inhibitors; Histamine; In Vitro Tech | 2004 |
LY-294002 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] affects calcium signaling in airway smooth muscle cells independently of phosphoinositide 3-kinase inhibition.
Topics: Androstadienes; Animals; Bronchi; Calcium; Calcium Signaling; Chromones; Dichlororibofuranosylbenzim | 2004 |
Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Azepines; Calcium; Cells, Cultured; Chromones; E | 2006 |
Insulin increases the expression of contractile phenotypic markers in airway smooth muscle.
Topics: Amides; Animals; Calcium-Binding Proteins; Calponins; Cattle; Cell Shape; Cells, Cultured; Chromones | 2007 |
Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism.
Topics: Adenine; Animals; Bronchial Hyperreactivity; Carbachol; Chromones; Class I Phosphatidylinositol 3-Ki | 2008 |
Novel inhibition of contractility by wortmannin in skeletal muscle.
Topics: Action Potentials; Androstadienes; Animals; Caffeine; Chromones; Cobra Cardiotoxin Proteins; Enzyme | 1998 |
Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle.
Topics: Amino Acid Sequence; Androstadienes; Animals; Benzoquinones; Calcium; Chromones; Colon; Egtazic Acid | 1998 |
Differential regulation of MAP kinase by contraction and insulin in skeletal muscle: metabolic implications.
Topics: Amino Acids; Androstadienes; Animals; Chromones; Enzyme Inhibitors; Flavonoids; Glucose; Glycogen Sy | 1999 |
Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle.
Topics: Animals; Chromones; Diglycerides; Esterification; Fatty Acids; Female; Hydrolysis; Insulin; Lipid Me | 2001 |
PI3-kinase/Akt modulates vascular smooth muscle tone via cAMP signaling pathways.
Topics: Animals; Carotid Arteries; Cattle; Chromones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzy | 2001 |
Contraction regulation of Akt in rat skeletal muscle.
Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Electrophoresis, P | 2002 |