2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Lymphoma, B-Cell in 7 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Lymphoma, B-Cell: A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malissein, E | 1 |
| Verdier, M | 1 |
| Ratinaud, MH | 1 |
| Troutaud, D | 1 |
| Uddin, S | 1 |
| Hussain, AR | 1 |
| Siraj, AK | 1 |
| Manogaran, PS | 1 |
| Al-Jomah, NA | 1 |
| Moorji, A | 1 |
| Atizado, V | 1 |
| Al-Dayel, F | 1 |
| Belgaumi, A | 1 |
| El-Solh, H | 1 |
| Ezzat, A | 1 |
| Bavi, P | 1 |
| Al-Kuraya, KS | 1 |
| Wang, J | 1 |
| Xu, YQ | 1 |
| Liang, YY | 1 |
| Gongora, R | 1 |
| Warnock, DG | 1 |
| Ma, HP | 1 |
| Pedersen, AE | 1 |
| Bregenholt, S | 1 |
| Johansen, B | 1 |
| Skov, S | 1 |
| Claesson, MH | 1 |
| Carey, GB | 1 |
| Scott, DW | 1 |
| Banerji, L | 1 |
| Glassford, J | 1 |
| Lea, NC | 1 |
| Thomas, NS | 1 |
| Klaus, GG | 1 |
| Lam, EW | 1 |
| Brennan, P | 1 |
| Mehl, AM | 1 |
| Jones, M | 1 |
| Rowe, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma[NCT01466868] | Phase 2 | 22 participants (Actual) | Interventional | 2011-11-30 | Terminated (stopped due to Regarding the comments of the iDSMB, the sponsor decided to stop the inclusions) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Lymphoma, B-Cell
| Article | Year |
|---|---|
Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells.
Topics: 14-3-3 Proteins; Animals; Apoptosis; B-Lymphocytes; bcl-Associated Death Protein; bcl-X Protein; Car | 2003 |
Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival.
Topics: Apoptosis; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; | 2006 |
An intermediate-conductance Ca(2+)-activated K (+) channel mediates B lymphoma cell cycle progression induced by serum.
Topics: Antigens, CD20; Calcium; Cell Cycle; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Flow Cytometry; | 2007 |
MHC-I-induced apoptosis in human B-lymphoma cells is dependent on protein tyrosine and serine/threonine kinases.
Topics: Androstadienes; Apoptosis; Benzoquinones; beta 2-Microglobulin; Calcium; Cell Division; Chromones; E | 1999 |
Role of phosphatidylinositol 3-kinase in anti-IgM- and anti-IgD-induced apoptosis in B cell lymphomas.
Topics: Animals; Antibodies, Anti-Idiotypic; Apoptosis; Cell Cycle Proteins; Chromones; Cyclin-Dependent Kin | 2001 |
BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.
Topics: Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocytes; Cell Cycle Proteins; Chromones; Cyclin D2; Cyc | 2001 |
Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells.
Topics: Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cell Survival; Chromones; Cyclin D; Cycl | 2002 |