2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Lymph Node Metastasis in 16 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "MDA-MB-231 breast cancer cells were exposed to IGF-1 with various concentrations." | 2.47 | PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer. ( Chen, Y; Dai, Y; Gu, Y; Qi, X; Sun, B; Zhu, C, 2011) |
| "The esophageal squamous cell carcinoma (ESCC) subtype with STMN1 overexpression has a high likelihood of lymphatic metastatic recurrence." | 1.48 | STMN1, a prognostic predictor of esophageal squamous cell carcinoma, is a marker of the activation of the PI3K pathway. ( Huang, S; Jiang, W; Song, L; Wang, Z, 2018) |
| "Livin expression in breast cancer correlated with the clinical stage and axillary lymph node metastasis and could be used as a prognostic marker." | 1.39 | Livin promotes progression of breast cancer through induction of epithelial-mesenchymal transition and activation of AKT signaling. ( Chen, L; Li, F; Li, HY; Luo, X; Ren, GS; Su, X; Wang, XY; Yin, X; Zheng, K, 2013) |
| "The supernatant of PC-3 prostate cancer cells facilitated tube-like formation in TR-LE cells, and formation was inhibited by neutralising antibodies against FGF-2." | 1.34 | Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. ( Koizumi, K; Matsuo, M; Saiki, I; Sakurai, H; Yamada, S, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 12 (75.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, M | 1 |
| Wang, J | 1 |
| Li, H | 1 |
| Zhang, Z | 2 |
| Cheng, Z | 1 |
| Bai, PS | 1 |
| Xia, N | 1 |
| Sun, H | 1 |
| Kong, Y | 1 |
| Jiang, W | 1 |
| Huang, S | 1 |
| Song, L | 1 |
| Wang, Z | 1 |
| Sun, C | 1 |
| Tao, Y | 1 |
| Gao, Y | 1 |
| Xia, Y | 1 |
| Liu, Y | 1 |
| Wang, G | 1 |
| Gu, Y | 2 |
| Li, F | 2 |
| Yin, X | 1 |
| Luo, X | 1 |
| Li, HY | 1 |
| Su, X | 1 |
| Wang, XY | 1 |
| Chen, L | 1 |
| Zheng, K | 1 |
| Ren, GS | 1 |
| Wu, J | 1 |
| Meng, J | 1 |
| Du, Y | 1 |
| Huang, Y | 1 |
| Jin, Y | 1 |
| Zhang, J | 1 |
| Wang, B | 1 |
| Zhang, Y | 3 |
| Sun, M | 1 |
| Tang, J | 1 |
| Xu, Z | 1 |
| Liu, D | 1 |
| Fan, C | 1 |
| Luan, L | 1 |
| Zhang, X | 1 |
| Wang, E | 1 |
| Zang, M | 1 |
| Zhang, B | 1 |
| Li, J | 2 |
| Su, L | 1 |
| Zhu, Z | 1 |
| Gu, Q | 1 |
| Liu, B | 1 |
| Yan, M | 1 |
| Hu, FW | 1 |
| Lee, SS | 1 |
| Yang, LC | 1 |
| Tsai, CH | 1 |
| Wang, TH | 1 |
| Chou, MY | 1 |
| Yu, CC | 1 |
| Zhu, C | 1 |
| Qi, X | 1 |
| Chen, Y | 1 |
| Sun, B | 1 |
| Dai, Y | 1 |
| Tarquinio, SB | 1 |
| Neiva, KG | 1 |
| Polverini, PJ | 1 |
| Nör, JE | 1 |
| Xiang, L | 1 |
| Xie, G | 1 |
| Ou, J | 1 |
| Wei, X | 1 |
| Pan, F | 1 |
| Liang, H | 1 |
| Li, A | 1 |
| Lu, D | 1 |
| Fang, Y | 1 |
| Sun, J | 1 |
| Tang, Y | 1 |
| Zhang, D | 1 |
| Fallavollita, L | 1 |
| Brodt, P | 1 |
| Matsuo, M | 1 |
| Yamada, S | 1 |
| Koizumi, K | 1 |
| Sakurai, H | 1 |
| Saiki, I | 1 |
| Jia, L | 1 |
| Yu, W | 1 |
| Wang, P | 1 |
| Sanders, BG | 1 |
| Kline, K | 1 |
1 review available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Lymph Node Metastasis
| Article | Year |
|---|---|
PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer.
Topics: Animals; Breast Neoplasms; Chromones; Female; Humans; Insulin-Like Growth Factor I; Lymphatic Metast | 2011 |
15 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Lymph Node Metastasis
| Article | Year |
|---|---|
AIM2 inhibits colorectal cancer cell proliferation and migration through suppression of Gli1.
Topics: Adenocarcinoma; Aged; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Color | 2020 |
Pleiotrophin, a target of miR-384, promotes proliferation, metastasis and lipogenesis in HBV-related hepatocellular carcinoma.
Topics: Adult; Carcinoma, Hepatocellular; Carrier Proteins; Cell Proliferation; Chromones; Cytokines; fas Re | 2017 |
STMN1, a prognostic predictor of esophageal squamous cell carcinoma, is a marker of the activation of the PI3K pathway.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Chromones; Esophageal Neoplasms; Esophageal Squamous Cel | 2018 |
F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT.
Topics: Aged; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Epithelial-Mesenchymal Transit | 2018 |
Livin promotes progression of breast cancer through induction of epithelial-mesenchymal transition and activation of AKT signaling.
Topics: Adaptor Proteins, Signal Transducing; Adult; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Mov | 2013 |
RACK1 promotes the proliferation, migration and invasion capacity of mouse hepatocellular carcinoma cell line in vitro probably by PI3K/Rac1 signaling pathway.
Topics: Animals; Anthracenes; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; | 2013 |
DIXDC1 increases the invasion and migration ability of non-small-cell lung cancer cells via the PI3K-AKT/AP-1 pathway.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromones; Fema | 2014 |
CEACAM6 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition via PI3K/AKT signaling pathway.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antigens, CD; Cadherins; Cell Adhesion Molecules; Cell Line | 2014 |
Knockdown of S100A4 impairs arecoline-induced invasiveness of oral squamous cell carcinomas.
Topics: Anthracenes; Areca; Carcinoma, Squamous Cell; Chromones; Enzyme Inhibitors; Female; Humans; Lymphati | 2015 |
Endothelial cell Bcl-2 and lymph node metastasis in patients with oral squamous cell carcinoma.
Topics: Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cells, Cultured; Chromones; Endothel | 2012 |
The extra domain A of fibronectin increases VEGF-C expression in colorectal carcinoma involving the PI3K/AKT signaling pathway.
Topics: Aged; Animals; Carcinoma; Cell Line, Tumor; Cells, Cultured; Chromones; Colorectal Neoplasms; Enzyme | 2012 |
Critical role of aquaporin-3 in epidermal growth factor-induced migration of colorectal carcinoma cells and its clinical significance.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Aquaporin 3; Butadienes; Carcinoma; Cell Movem | 2013 |
Vascular endothelial growth factor C expression and lymph node metastasis are regulated by the type I insulin-like growth factor receptor.
Topics: Animals; Carcinoma, Lewis Lung; Chromones; Endothelial Growth Factors; Enzyme Inhibitors; Flavonoids | 2003 |
Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells.
Topics: Animals; Cell Communication; Chromones; Endothelial Cells; Enzyme Inhibitors; Fibroblast Growth Fact | 2007 |
In vivo and in vitro studies of anticancer actions of alpha-TEA for human prostate cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Li | 2008 |