2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Leukemia, Basophilic, Acute in 5 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Leukemia, Basophilic, Acute: A rare acute myeloid leukemia in which the primary differentiation is to BASOPHILS. It is characterized by an extreme increase of immature basophilic granulated cells in the bone marrow and blood. Mature basophils are usually sparse.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found that in a human erythroleukemia cell line, as well as in rabbit platelets, PI 3-kinase and PKCdelta associate in a specific manner that is modulated by cell activation." | 1.29 | Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. ( Duronio, V; Ettinger, SL; Lauener, RW, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Itoh, T | 1 |
| Ohguchi, K | 1 |
| Iinuma, M | 1 |
| Nozawa, Y | 1 |
| Akao, Y | 1 |
| Yano, H | 1 |
| Agatsuma, T | 1 |
| Nakanishi, S | 1 |
| Saitoh, Y | 1 |
| Fukui, Y | 1 |
| Nonomura, Y | 1 |
| Matsuda, Y | 1 |
| Ettinger, SL | 1 |
| Lauener, RW | 1 |
| Duronio, V | 1 |
| Hirasawa, N | 1 |
| Sato, Y | 1 |
| Fujita, Y | 1 |
| Mue, S | 1 |
| Ohuchi, K | 1 |
| Straube, S | 1 |
| Parekh, AB | 1 |
5 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Leukemia, Basophilic, Acute
| Article | Year |
|---|---|
Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation.
Topics: Animals; Calcium; Cell Degranulation; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regu | 2008 |
Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in Fc epsilon RI-mediated signal transduction.
Topics: Androstadienes; Animals; Aorta; Chromones; Enzyme Inhibitors; Histamine Antagonists; Histamine Relea | 1995 |
Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation.
Topics: Androstadienes; Animals; Blood Platelets; Cell Line; Chromones; Cytokines; Enzyme Inhibitors; Granul | 1996 |
Inhibition by dexamethasone of antigen-induced c-Jun N-terminal kinase activation in rat basophilic leukemia cells.
Topics: Androstadienes; Animals; Anti-Inflammatory Agents; Calcium-Calmodulin-Dependent Protein Kinases; Chr | 1998 |
Effects of phosphatidylinositol kinase inhibitors on the activation of the store-operated calcium current ICRAC in RBL-1 cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Animals; Calcium; Chromones; Enzyme Inhibitors; Leu | 2001 |