2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Leiomyosarcoma, Epithelioid in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uterine leiomyosarcoma is a severe neoplasia resistant to conventional therapies." | 1.42 | LY294002 induces in vitro apoptosis and overexpression of p75NTR in human uterine leiomyosarcoma HTB 114 cells. ( Crispoltoni, L; Montagnoli, C; Pistilli, A; Rende, M; Stabile, AM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pistilli, A | 1 |
| Rende, M | 1 |
| Crispoltoni, L | 1 |
| Montagnoli, C | 1 |
| Stabile, AM | 1 |
| Blanco-Aparicio, C | 1 |
| Pequeño, B | 1 |
| Moneo, V | 1 |
| Romero, L | 1 |
| Leal, JF | 1 |
| Velasco, J | 1 |
| Fominaya, J | 1 |
| Carnero, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role and Clinical Relevance of Nerve Growth Factor (NGF) and Its Receptors (TrKA and p75NTR) in Patients With Erectile Dysfunction and Diabetes With or Wothout Metabolic Syndrome[NCT03862547] | 40 participants (Anticipated) | Interventional | 2019-01-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Leiomyosarcoma, Epithelioid
| Article | Year |
|---|---|
LY294002 induces in vitro apoptosis and overexpression of p75NTR in human uterine leiomyosarcoma HTB 114 cells.
Topics: Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Activation; Enz | 2015 |
Inhibition of phosphatidylinositol-3-kinase synergizes with gemcitabine in low-passage tumor cell lines correlating with Bax translocation to the mitochondria.
Topics: bcl-2-Associated X Protein; bcl-X Protein; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2005 |