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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Keloid

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Keloid in 3 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.

Research Excerpts

ExcerptRelevanceReference
"Keloid is one of the most frustrating problems related to wounding healing and presents a great challenge in clinic."1.46Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts. ( An, G; Liang, S; Liu, Y; Sheng, C; Yao, W, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
An, G1
Liang, S1
Sheng, C1
Liu, Y1
Yao, W1
Lim, IJ2
Phan, TT2
Tan, EK1
Nguyen, TT1
Tran, E1
Longaker, MT1
Song, C1
Lee, ST1
Huynh, HT1
Khoo, YT1
Ong, CT1
Mukhopadhyay, A1
Han, HC1
Do, DV1

Other Studies

3 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Keloid

ArticleYear
Upregulation of microRNA-205 suppresses vascular endothelial growth factor expression-mediated PI3K/Akt signaling transduction in human keloid fibroblasts.
    Experimental biology and medicine (Maywood, N.J.), 2017, Volume: 242, Issue:3

    Topics: Adolescent; Adult; Cell Line; Cell Survival; Child, Preschool; Chromones; Female; Fibroblasts; Human

2017
Synchronous activation of ERK and phosphatidylinositol 3-kinase pathways is required for collagen and extracellular matrix production in keloids.
    The Journal of biological chemistry, 2003, Oct-17, Volume: 278, Issue:42

    Topics: Blotting, Western; Butadienes; Cell Division; Chromones; Coculture Techniques; Collagen; Culture Med

2003
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis.
    Journal of cellular physiology, 2006, Volume: 208, Issue:2

    Topics: Benzamides; Chromones; Coculture Techniques; Connective Tissue Growth Factor; Culture Media, Conditi

2006