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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Insulinoma

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Insulinoma in 3 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Insulinoma: A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
"This study demonstrated gemcitabine-induced cytotoxicity in the insulinoma cell line INS-1."7.78Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1. ( Motoshige, H; Oyama, K; Sakurai, K; Takahashi, K, 2012)
"This study demonstrated gemcitabine-induced cytotoxicity in the insulinoma cell line INS-1."3.78Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1. ( Motoshige, H; Oyama, K; Sakurai, K; Takahashi, K, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Motoshige, H1
Oyama, K1
Takahashi, K1
Sakurai, K1
Beeharry, N1
Chambers, JA1
Green, IC1
Collier, JJ1
White, SM1
Dick, GM1
Scott, DK1

Other Studies

3 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Insulinoma

ArticleYear
Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:11

    Topics: Androstadienes; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Death; Cell Line, Tumor; C

2012
Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition.
    Apoptosis : an international journal on programmed cell death, 2004, Volume: 9, Issue:5

    Topics: Androstadienes; Animals; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Chromones; Enzyme I

2004
Phosphatidylinositol 3-kinase inhibitors reveal a unique mechanism of enhancing insulin secretion in 832/13 rat insulinoma cells.
    Biochemical and biophysical research communications, 2004, Nov-19, Volume: 324, Issue:3

    Topics: Action Potentials; Androstadienes; Animals; Calcium; Cell Line, Tumor; Chromones; Dose-Response Rela

2004