2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Injuries, Spinal Cord in 16 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "We established a spinal cord contusion model of SCI in all experimental groups except controls, in which only a laminectomy was performed." | 1.40 | Anti-apoptotic signal transduction mechanism of electroacupuncture in acute spinal cord injury. ( Disheng, Y; Jinwei, X; Liang, Z; Mengxuan, D; Renfu, Q; Rongliang, C; Zongbao, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 11 (68.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, H | 1 |
| Zheng, Z | 2 |
| Han, W | 1 |
| Yuan, Y | 1 |
| Li, Y | 2 |
| Zhou, K | 1 |
| Wang, Q | 3 |
| Xie, L | 1 |
| Xu, K | 1 |
| Zhang, H | 3 |
| Xu, H | 2 |
| Wu, Y | 1 |
| Xiao, J | 3 |
| Wang, Z | 3 |
| Zheng, S | 1 |
| Gu, Y | 1 |
| Zhou, L | 1 |
| Lin, B | 1 |
| Liu, W | 1 |
| Chen, J | 2 |
| Chen, Y | 1 |
| Khor, S | 1 |
| Shi, K | 1 |
| He, Z | 1 |
| Zhao, Y | 1 |
| Li, X | 2 |
| Li, J | 1 |
| Yin, J | 1 |
| Wang, X | 1 |
| Lu, T | 1 |
| Wu, X | 1 |
| Wei, N | 1 |
| Liu, X | 1 |
| Zhou, Y | 2 |
| Shang, C | 1 |
| Duan, Y | 1 |
| Dong, Y | 1 |
| Chen, Z | 1 |
| Li, Z | 1 |
| Jiang, C | 1 |
| Jiang, X | 1 |
| Zhang, J | 1 |
| Renfu, Q | 1 |
| Rongliang, C | 1 |
| Mengxuan, D | 1 |
| Liang, Z | 1 |
| Jinwei, X | 1 |
| Zongbao, Y | 1 |
| Disheng, Y | 1 |
| Hu, R | 1 |
| Ge, H | 1 |
| Duanmu, W | 1 |
| Xue, X | 1 |
| Hu, S | 1 |
| Feng, H | 1 |
| Bareiss, SK | 1 |
| Dugan, E | 1 |
| Brewer, KL | 1 |
| Zheng, B | 1 |
| Ye, L | 1 |
| Zhu, S | 1 |
| Shi, H | 1 |
| Chen, D | 1 |
| Wei, X | 1 |
| Wang, C | 1 |
| Wang, P | 1 |
| Zeng, W | 1 |
| Li, W | 1 |
| Shi, Y | 1 |
| Quan, R | 1 |
| Li, C | 1 |
| Zhang, L | 1 |
| Du, M | 1 |
| Xu, J | 1 |
| Yang, Z | 1 |
| Yang, D | 1 |
| Codeluppi, S | 1 |
| Svensson, CI | 1 |
| Hefferan, MP | 1 |
| Valencia, F | 1 |
| Silldorff, MD | 1 |
| Oshiro, M | 1 |
| Marsala, M | 1 |
| Pasquale, EB | 1 |
| Paterniti, I | 1 |
| Esposito, E | 1 |
| Mazzon, E | 1 |
| Bramanti, P | 1 |
| Cuzzocrea, S | 1 |
| Zhang, S | 1 |
| Huan, W | 1 |
| Wei, H | 1 |
| Shi, J | 1 |
| Fan, J | 1 |
| Zhao, J | 1 |
| Shen, A | 1 |
| Teng, H | 1 |
| Pannu, R | 1 |
| Singh, AK | 1 |
| Singh, I | 1 |
| Yu, F | 1 |
| Narasimhan, P | 1 |
| Saito, A | 1 |
| Liu, J | 1 |
| Chan, PH | 1 |
16 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Injuries, Spinal Cord
| Article | Year |
|---|---|
Metformin Promotes Axon Regeneration after Spinal Cord Injury through Inhibiting Oxidative Stress and Stabilizing Microtubule.
Topics: Animals; Axons; Chromones; Metformin; Microtubules; Mitochondria; Morpholines; NF-E2-Related Factor | 2020 |
4-PBA Enhances Autophagy by Inhibiting Endoplasmic Reticulum Stress in Recombinant Human Beta Nerve Growth Factor-Induced PC12 cells After Mechanical Injury via PI3K/AKT/mTOR Signaling Pathway.
Topics: Animals; Autophagy; Chromones; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Hu | 2020 |
Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury.
Topics: Animals; Apoptosis; Chromones; Disease Models, Animal; Fibroblast Growth Factor 10; Gene Expression | 2017 |
Lipoxin A4 protects against spinal cord injury via regulating Akt/nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 signaling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Disease Models, Animal; Gene Expression | 2018 |
MiR-92b-3p promotes neurite growth and functional recovery via the PTEN/AKT pathway in acute spinal cord injury.
Topics: Animals; Apoptosis; Chromones; GAP-43 Protein; Gene Expression; Humans; MicroRNAs; Morpholines; Neur | 2019 |
Anti-apoptotic signal transduction mechanism of electroacupuncture in acute spinal cord injury.
Topics: Animals; Apoptosis; Caspase 3; Chromones; Cytochromes c; Electroacupuncture; Female; Flavonoids; Mal | 2014 |
G-protein-coupled receptor 30-mediated antiapoptotic effect of estrogen on spinal motor neurons following injury and its underlying mechanisms.
Topics: Animals; Apoptosis; Cells, Cultured; Chromones; Estradiol; Male; Microscopy, Fluorescence; Models, B | 2015 |
PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias.
Topics: Animals; Chromones; Enzyme Activation; Ganglia, Spinal; Glycogen Synthase Kinase 3; Glycogen Synthas | 2015 |
Epidermal growth factor attenuates blood-spinal cord barrier disruption via PI3K/Akt/Rac1 pathway after acute spinal cord injury.
Topics: Adherens Junctions; Animals; Chromones; Endothelial Cells; Epidermal Growth Factor; Female; Glucose; | 2016 |
Tetramethylpyrazine improves the recovery of spinal cord injury via Akt/Nrf2/HO-1 pathway.
Topics: Animals; Apoptosis; Caspase 3; Chromones; Cytokines; Heme Oxygenase-1; Locomotion; Male; Morpholines | 2016 |
The study of traditional Chinese medical elongated-needle therapy promoting neurological recovery mechanism after spinal cord injury in rats.
Topics: Acupuncture Therapy; Animals; bcl-2-Associated X Protein; Caspase 3; Chromones; Cytochromes c; Cytok | 2016 |
The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord.
Topics: Analysis of Variance; Animals; Astrocytes; Cells, Cultured; Chromones; Disease Models, Animal; Enzym | 2009 |
Evidence for the role of PI(3) -kinase-AKT-eNOS signalling pathway in secondary inflammatory process after spinal cord compression injury in mice.
Topics: Animals; bcl-2-Associated X Protein; Chromones; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Pro | 2011 |
FOXO3a/p27kip1 expression and essential role after acute spinal cord injury in adult rat.
Topics: Animals; Astrocytes; Axons; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Fo | 2013 |
A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma.
Topics: Animals; Antigens, CD; Astrocytes; Cell Proliferation; Cells, Cultured; Chromones; Enzyme Activation | 2005 |
Increased expression of a proline-rich Akt substrate (PRAS40) in human copper/zinc-superoxide dismutase transgenic rats protects motor neurons from death after spinal cord injury.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Genetically Modified; Brain Ischemia; Cell D | 2008 |